Role of mitochondria in alcoholic liver injury

Mitochondria and Apoptosis

1998 • 8,909 citations

The mitochondrial permeability transition

1995 • 2,412 citations

Mitochondrial control of apoptosis

1997 • 1,500 citations

Bax interacts with the permeability transition pore to induce permeability transition and cytochromecrelease in isolated mitochondria

1998 • 932 citations

Mitochondria as regulators of apoptosis: doubt no more

1998 • 838 citations

The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death

1996 • 420 citations

Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor

1998 • 361 citations

Hepatocyte apoptosis is a pathologic feature of human alcoholic hepatitis

2001 • 271 citations

Impaired uptake of glutathione by hepatic mitochondria from chronic ethanol-fed rats. Tracer kinetic studies in vitro and in vivo and susceptibility to oxidant stress.

1991 • 247 citations

Oxidative stress-mediated apoptosis of hepatocytes exposed to acute ethanol intoxication

1997 • 221 citations

Effects of Oral S-Adenosyl-l-Methionine on Hepatic Glutathione in Patients with Liver Disease

1989 • 207 citations

Increased loss and decreased synthesis of hepatic glutathione after acute ethanol administration. Turnover studies

1985 • 204 citations

Oxidative stress and liver disease.

1996 • 143 citations

Pathogenesis of alcoholic liver disease with particular emphasis on oxidative stress

1997 • 129 citations

The mitochondrial permeability transition contributes to acute ethanol-induced apoptosis in rat hepatocytes

2001 • 129 citations

Oxidative stress on mitochondria and cell membrane of cultured rat hepatocytes and perfused liver exposed to ethanol

1997 • 122 citations

Ethanol‐Induced Apoptosis to Stable HepG2 Cell Lines Expressing Human Cytochrome P‐4502E1

1999 • 112 citations

Apoptosis and Alcoholic Liver Disease

1998 • 105 citations

Subcellular changes and apoptosis induced by ethanol in rat liver

1988 • 93 citations

Potentiation by Chronic Ethanol Treatment of the Mitochondrial Permeability Transition

1999 • 77 citations

Acute ethanol intoxication stimulates superoxide anion production byin situ perfused rat liver

1992 • 75 citations

Lipid hydroperoxide induced mitochondrial dysfunction following acute ethanol intoxication in rats

1994 • 57 citations