Regulation of the salvage pathway of deoxynucleotides synthesis in apoptosis induced by growth factor deprivation

Cytokine receptor signalling

1995 • 1,242 citations

Apoptosis and Programmed Cell Death in Immunity

1992 • 1,105 citations

The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells

1989 • 1,097 citations

Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis

1990 • 945 citations

INTERACTIONS BETWEEN DEOXYRIBONUCLEOTIDE AND DNA SYNTHESIS

1988 • 773 citations

IL3-dependent mouse clones that express B-220 surface antigen, contain ig genes in germ-line configuration, and generate B lymphocytes in vivo

1985 • 718 citations

Programmed cell death and Bcl-2 protection in the absence of a nucleus.

1994 • 560 citations

bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs.

1992 • 487 citations

Signal transduction by the high-affinity GM-CSF receptor: two distinct cytoplasmic regions of the common beta subunit responsible for different signaling.

1993 • 383 citations

Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors.

1995 • 321 citations

Ribonucleotide reductase: regulation, regulation, regulation

1992 • 305 citations

Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.

1995 • 294 citations

Low levels of deoxynucleotides in peripheral blood lymphocytes: a strategy to inhibit human immunodeficiency virus type 1 replication.

1993 • 287 citations

Deoxyribonucleoside triphosphate imbalance. 5-Fluorodeoxyuridine-induced DNA double strand breaks in mouse FM3A cells and the mechanism of cell death.

1987 • 251 citations

Regulation of apoptosis in interleukin-3-dependent hemopoietic cells by interleukin-3 and calcium ionophores.

1990 • 226 citations

Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents.

1992 • 224 citations

Changes of deoxyribonucleoside triphosphate pools induced by hydroxyurea and their relation to DNA synthesis.

1986 • 215 citations

A method for the determination of dATP and dTTP in picomole amounts

1970 • 206 citations

The Panspecific Hemopoietin of Activated T Lymphocytes (Interleukin-3)

1986 • 149 citations

Frameshift errors initiated by nucleotide misincorporation.

1990 • 136 citations

Highly synchronous culture of fibroblasts from G2 block caused by staurosporine, a potent inhibitor of protein kinases

1991 • 129 citations

Interleukin 3 stimulates proliferation via protein kinase C activation without increasing inositol lipid turnover.

1988 • 108 citations

Adenosine, deoxyadenosine, and deoxyguanosine induce DNA cleavage in mouse thymocytes.

1988 • 103 citations

Properties and levels of deoxynucleoside kinases in normal and tumor cells; implications for chemotherapy

1994 • 75 citations

Detection of activities that interfere with the enzymatic assay of deoxyribonucleoside 5'-triphosphates.

1980 • 73 citations

Regulation of pyrimidine deoxyribonucleotide metabolism by substrate cycles in dCMP deaminase-deficient V79 hamster cells.

1987 • 69 citations

DNA precursor asymmetries, replication fidelity, and variable genome evolution

1992 • 68 citations

Differential phosphorylation of human thymidine kinase in proliferating and M phase-arrested human cells.

1994 • 53 citations

A convenient assay for ADP reductase activity using Dowex-1-borate columns

1973 • 50 citations

Reversible abrogation of IL-3 dependence by an inducible H-ras oncogene.

1989 • 48 citations

Gene-Specific and Strand-Specific DNA Repair in the G₁ and G₂ Phases of the Cell Cycle

1995 • 40 citations

Mutations induced at the hypoxanthine-guanine phosphoribosyltransferase locus of human T-lymphoblasts by perturbations of purine deoxyribonucleoside triphosphate pools.

1990 • 39 citations

The regulation of thymidine kinase in HL-60 human promyeloleukemia cells.

1993 • 28 citations

Effects of deoxycytidine and thymidine kinase deficiency on substrate cycles between deoxyribonucleosides and their 5'-phosphates.

1988 • 28 citations

DNA fragmentation, dATP pool elevation and potentiation of antifolate cytotoxicity in L1210 cells by hypoxanthine

1992 • 25 citations

[47] Thymidine kinase from blast cells of myelocytic leukemia

1978 • 24 citations

Expression of thymidine kinase is essential to low dose radiation resistance of rat glioma cells.

1994 • 23 citations

Bcl-2 Oncogene Protects a Bone Marrow-Derived Pre-B Cell Line from 5′-Fluor,2′-deoxyuridine-Induced Apoptosis

1993 • 22 citations

Human IL-3 receptor signaling: rapid induction of phosphatidylcholine hydrolysis is independent of protein kinase C but dependent on tyrosine phosphorylation in transfected NIH 3T3 cells.

1995 • 20 citations

Interleukin‐3 and Bcl‐2 cooperatively inhibit etoposide‐induced apoptosis in a murine pre‐B cell line

1994 • 18 citations

Regulation of Pyrimidine Deoxyribonucleotide Metabolism by Substrate Cycles in dCMP Deaminase-Deficient V79 Hamster Cells

1987 • 17 citations

Deoxynucleotide pools and DNA synthesis in resting and PHA-stimulated human lymphocytes treated with mutagens

1992 • 15 citations

Constitutive overexpression of DNA binding activity to the distal CCAAT box of human thymidine kinase promoter in human tumor cell lines.

1993 • 12 citations

Temperature-Sensitive DNA Mutant of Chinese Hamster Ovary Cells with a Thermolabile Ribonucleotide Reductase Activity

1990 • 10 citations

Growth Inhibition of Kirkman-Robbins Hepatoma by l-(l,3-Dihydroxy-2-propoxymethyl)-5,6-tetramethyIeneuraciI and Possible Mechanism of its Biological Activity

1989 • 7 citations