Estrogen and the Vascular Injury Response

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.

1995 • 1,762 citations

Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives

1994 • 1,348 citations

Induction of calcium-dependent nitric oxide synthases by sex hormones.

1994 • 1,074 citations

Estrogen Improves Endothelium-Dependent, Flow-Mediated Vasodilation in Postmenopausal Women

1994 • 708 citations

Induction and Stabilization of IκBα by Nitric Oxide Mediates Inhibition of NF-κB

1995 • 707 citations

Superoxide and peroxynitrite inatherosclerosis.

1994 • 674 citations

Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression.

1992 • 653 citations

Local Delivery of Vascular Endothelial Growth Factor Accelerates Reendothelialization and Attenuates Intimal Hyperplasia in Balloon-Injured Rat Carotid Artery

1995 • 551 citations

Ethinyl estradiol acutely attenuates abnormal coronary vasomotor responses to acetylcholine in postmenopausal women.

1994 • 540 citations

Adventitial Myofibroblasts Contribute to Neointimal Formation in Injured Porcine Coronary Arteries

1996 • 536 citations

Identification and Localization of Alternately Spliced mRNAs for Vascular Endothelial Growth Factor in Human Uterus and Estrogen Regulation in Endometrial Carcinoma Cell Lines1

1993 • 453 citations

Vascular endothelial growth factor/vascular permeability factor expression in the rat uterus: rapid stimulation by estrogen correlates with estrogen-induced increases in uterine capillary permeability and growth.

1993 • 437 citations

The epidemiology of coronary heart disease and estrogen replacement in postmenopausal women

1995 • 423 citations

Medroxyprogesterone Acetate Antagonizes Inhibitory Effects of Conjugated Equine Estrogens on Coronary Artery Atherosclerosis

1997 • 377 citations

Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits.

1996 • 375 citations

Adventitial Remodeling After Coronary Arterial Injury

1996 • 353 citations

Effects of 17beta-estradiol on cytokine-induced endothelial cell adhesion molecule expression.

1996 • 351 citations

Estrogens as natural antioxidants of membrane phospholipid peroxidation

1987 • 329 citations

Effect of 17 beta-estradiol on endothelium-dependent responses in the rabbit.

1988 • 320 citations

Circulating Nitric Oxide (Nitrite/Nitrate) Levels in Postmenopausal Women Substituted With 17β-Estradiol and Norethisterone Acetate

1995 • 263 citations

Estrogen Reduces Myointimal Proliferation After Balloon Injury of Rat Carotid Artery

1996 • 260 citations

Ethinylestradiol does not enhance the expression of nitric oxide synthase in bovine endothelial cells but increases the release of bioactive nitric oxide by inhibiting superoxide anion production.

1996 • 259 citations

Human Endothelial Nitric Oxide Synthase Gene Transfer Inhibits Vascular Smooth Muscle Cell Proliferation and Neointima Formation After Balloon Injury in Rats

1998 • 240 citations

17 beta-estradiol preserves endothelial vasodilator function and limits low-density lipoprotein oxidation in hypercholesterolemic swine.

1994 • 240 citations

Estradiol Accelerates Functional Endothelial Recovery After Arterial Injury

1997 • 238 citations

The inhibition of low-density lipoprotein oxidation by 17-β estradiol

1992 • 211 citations

Estrogens inhibit copper and cell-mediated modification of low density lipoprotein

1991 • 186 citations

Endothelial-dependent coronary vasomotor responsiveness in postmenopausal women with and without estrogen replacement therapy

1994 • 185 citations

Estrogen modulation of JE/monocyte chemoattractant protein-1 mRNA expression in murine macrophages.

1995 • 180 citations

Induction of nitric oxide synthases early in pregnancy

1994 • 165 citations

Induction of Vascular Endothelial Growth Factor in Balloon-Injured Baboon Arteries

1997 • 158 citations

Nitric Oxide Attenuates Vascular Smooth Muscle Cell Activation by Interferon-γ

1996 • 145 citations

Protective effect of estrogens and catecholestrogens against peroxidative membrane damagein vitro

1995 • 145 citations

Effects of estrogen replacement therapy on peripheral vasomotor function in postmenopausal women

1995 • 143 citations

Potential role of the adventitia in arteritis and atherosclerosis

1996 • 143 citations

Effects of estrogens on lipoprotein metabolism and cardiovascular disease in women

1994 • 136 citations

Probucol inhibits neointimal thickening and macrophage accumulation after balloon injury in the cholesterol-fed rabbit.

1992 • 130 citations

Medroxyprogesterone Attenuates Estrogen-Mediated Inhibition of Neointima Formation After Balloon Injury of the Rat Carotid Artery

1996 • 127 citations

Organization of the bovine gene encoding the endothelial nitric oxide synthase

1994 • 124 citations

Vascular endothelial growth factor/vascular permeability factor expression in the rat uterus: rapid stimulation by estrogen correlates with estrogen-induced increases in uterine capillary permeability and growth

1993 • 118 citations

Estradiol inhibition of arterial neointimal hyperplasia after balloon injury

1994 • 117 citations

Novel and potent biological antioxidants on membrane phospholipid peroxidation: 2-hydroxy estrone and 2-hydroxy estradiol

1987 • 110 citations

Overexpression of Human Endothelial Nitric Oxide Synthase in Rat Vascular Smooth Muscle Cells and in Balloon-Injured Carotid Artery

1998 • 108 citations

Sexually Dimorphic Response of the Balloon-Injured Rat Carotid Artery to Hormone Treatment

1997 • 101 citations

Differential Effects of Hormone-Replacement Therapy on Endogenous Nitric Oxide (Nitrite/Nitrate) Levels in Postmenopausal Women Substituted with 17β-Estradiol Valerate and Cyproterone Acetate or Medroxyprogesterone Acetate¹

1997 • 100 citations

Contribution of Sustained Ca2+ Elevation for Nitric Oxide Production in Endothelial Cells and Subsequent Modulation of Ca 2+ Transient in Vascular Smooth Muscle Cells in Coculture

1996 • 99 citations

Estrogen Restores Endothelial Cell Function in an Experimental Model of Vascular Injury

1997 • 92 citations

Non-genomic effects of estrogen and the vessel wall

1996 • 92 citations

Effect of alpha-tocopherol on restenosis after angioplasty in a model of experimental atherosclerosis.

1995 • 90 citations

Inhibition of macrophage-dependent low density lipoprotein oxidation by nitric-oxide donors.

1995 • 88 citations

Mechanisms of vascular preservation by a novel NO donor following rat carotid artery intimal injury

1995 • 86 citations

Adeno-associated virus vectors for vascular gene delivery.

1997 • 80 citations

The clinical aspects of estrogen and the cardiovascular system

1996 • 76 citations

Nitric oxide donor compounds inhibit the toxicity of oxidized low‐density lipoprotein to endothelial cells

1995 • 75 citations

Different Effects of Estrogen and Progesterone on Experimental Atherosclerosis inFemale Versus Male Rabbits

1996 • 74 citations

Estrogen reduces proliferation and agonist-induced calcium increase in coronary artery smooth muscle cells

1997 • 73 citations

Estrogen: Effects on the cardiovascular tree

1996 • 60 citations

Time course and cellular characteristics of the iliac artery response to acute balloon injury. An angiographic, morphometric, and immunocytochemical analysis in the cholesterol-fed New Zealand white rabbit.

1992 • 48 citations

Basic Fibroblast Growth Factor Restores Endothelium-Dependent Responses After Balloon Injury of Rabbit Arteries

1996 • 45 citations

Physiological concentration of 17 beta-estradiol inhibits chemotaxis of human monocytes in response to monocyte chemotactic protein 1.

1996 • 41 citations

Heart rate and heart rate variability changes induced by right atrial pacing

1996 • 36 citations

Effects of estrogen on cardiovascular responses of premenopausal monkeys.

1994 • 35 citations

Sex hormones, lipoproteins, and vascular reactivity

1995 • 33 citations

Differential Effects of Hormone-Replacement Therapy on Endogenous Nitric Oxide (Nitrite/Nitrate) Levels in Postmenopausal Women Substituted with 17 -Estradiol Valerate and Cyproterone Acetate or Medroxyprogesterone Acetate

1997 • 30 citations

Evidence for NO involvement in regulating vascular reactivity in balloon-injured rat carotid artery

1995 • 17 citations

Gender and Cardiovascular Disease

1997 • 14 citations

Endocrinology of Cardiovascular Function

1998 • 13 citations

Effects of Sex Steroids in Vascular Injury

1998 • 7 citations

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