Keratin 19: Predicted amino acid sequence and broad tissue distribution suggest it evolved from keratinocyte keratins

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells

1982 • 5,272 citations

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1986 • 4,785 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

High resolution two-dimensional electrophoresis of basic as well as acidic proteins

1977 • 3,556 citations

Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis

1983 • 2,609 citations

Efficient isolation of genes by using antibody probes.

1983 • 2,065 citations

The packing of α-helices: simple coiled-coils

1953 • 1,549 citations

Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells.

1986 • 1,378 citations

Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies

1982 • 777 citations

Automation of the computer handling of gel reading data produced by the shotgun method of DNA sequencing

1982 • 744 citations

All classes of intermediate filaments share a common antigenic determinant defined by a monoclonal antibody

1981 • 654 citations

India ink staining of proteins on nitrocellulose paper

1983 • 613 citations

Easy identification of cDNA clones.

1983 • 587 citations

Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles.

1983 • 568 citations

Monoclonal antibodies provide specific intramolecular markers for the study of epithelial tonofilament organization.

1982 • 477 citations

Patterns of Expression and Organization of Cytokeratin Intermediate Filaments

1985 • 420 citations

Complete amino acid sequence of a mouse epidermal keratin subunit and implications for the structure of intermediate filaments

1983 • 336 citations

Keratin Antigens in Differentiating Skin

1985 • 330 citations

The cDNA sequence of a human epidermal keratin: Divergence of sequence but conservation of structure among intermediate filament proteins

1982 • 298 citations

Expression of epidermal keratins and filaggrin during human fetal skin development.

1985 • 284 citations

Different keratin polypeptides in epidermis and other epithelia of human skin: a specific cytokeratin of molecular weight 46,000 in epithelia of the pilosebaceous tract and basal cell epitheliomas.

1982 • 278 citations

A new small (40 kd) keratin filament protein made by some cultured human squamous cell carcinomas

1981 • 254 citations

EPIDERMAL WOUND HEALING.

1973 • 248 citations

Intermediate Filaments: Conformity and Diversity of Expression and Structure

1985 • 246 citations

Identification of Merkel cells in human skin by specific cytokeratin antibodies:

1984 • 246 citations

Changes in the Pattern of Cytokeratin Polypeptides in Epidermis and Hair Follicles During Skin Development in Human Fetuses

1982 • 230 citations

Cytokeratins of normal epithelia and some neoplasms of the female genital tract.

1983 • 224 citations

Intermediate filament forming ability of desmin derivatives lacking either the amino-terminal 67 or the carboxy-terminal 27 residues

1985 • 193 citations

Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues II. Concomitant and mutually exclusive synthesis of trichocytic and epithelial cytokeratins in diverse human and bovine tissues (hair follicle, nail bed and matrix, lingual papilla, thymic reticulum)

1988 • 189 citations

Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins

1987 • 187 citations

Amino acid sequences of mouse and human epidermal type II keratins of Mr 67,000 provide a systematic basis for the structural and functional diversity of the end domains of keratin intermediate filament subunits.

1985 • 183 citations

Amino acid sequence and gene organization of cytokeratin no. 19, an exceptional tail-less intermediate filament protein.

1986 • 167 citations

Effects of SV40 transformation on the cytoskeleton and behavioural properties of human keratinocytes

1982 • 165 citations

Monoclonal anti-cytokeratin antibody from a hybridoma clone generated by electrofusion

1985 • 160 citations

Differential expression of keratin 19 in normal human epithelial tissues revealed by monospecific monoclonal antibodies

1986 • 160 citations

Differentiation-related changes of cytokeratin expression in cultured keratinocytes and in fetal, newborn, and adult epidermis

1987 • 159 citations

Highly conserved sequencim in the 3′ untranslated region of mRNAs coding for homologous proteins in distantly related species

1985 • 155 citations

A program for prediction of protein secondary structure from nucleotide sequence data: application to histocompatibility antigens

1984 • 150 citations

Paget's disease of the nipple: A ten year review including clinical, pathological, and immunohistochemical findings

1986 • 148 citations

PATTERNS OF EXPRESSION OF KERATIN 19 AS DETECTED WITH MONOCLONAL ANTIBODIES IN HUMAN BREAST TISSUES AND TUMOURS

1985 • 146 citations

A subclass of luminal epithelial cells in the human mammary gland, defined by antibodies to cytokeratins

1985 • 142 citations

A group of type I keratin genes on human chromosome 17: characterization and expression.

1988 • 142 citations

Molecular characterization and expression of the stratification-related cytokeratins 4 and 15.

1988 • 140 citations

Molecular cloning and characterization of the Endo B cytokeratin expressed in preimplantation mouse embryos.

1986 • 136 citations

Cloning of cDNAs specifying vitamin A-responsive human keratins.

1984 • 127 citations

Cytokeratin expression in squamous metaplasia of the human uterine cervix

1986 • 127 citations

Cytokeratin expression in simple epithelia

1986 • 124 citations

Amino acid sequence data on glial fibrillary acidic protein (GFA); implications for the subdivision of intermediate filaments into epithelial and non-epithelial members.

1983 • 111 citations

Hybrid character of a large neurofilament protein (NF-M): intermediate filament type sequence followed by a long and acidic carboxy-terminal extension.

1984 • 110 citations

Identification of two types of keratin polypeptides within the acidic cytokeratin subfamily I

1984 • 95 citations

Comparison of mouse and human keratin 18: A component of intermediate filaments expressed prior to implantation

1986 • 89 citations

Different patterns of cytokeratin expression in the normal epithelia of the upper respiratory tract

1985 • 88 citations

Regeneration and Dose–response Characteristics of Irradiated Mouse Dorsal Epidermal Cells

1976 • 81 citations

Paget’s Cells: New Evidence Linking Mammary and Extramammary Paget Cells to a Common Cell Phenotype

1985 • 80 citations

The borderland between caries and periodontal disease iii

1987 • 74 citations

Evolution of keratin genes: Different protein domains evolve by different pathways

1987 • 67 citations

Stage-specific keratins in Xenopus laevis embryos and tadpoles: the XK81 gene family.

1986 • 65 citations

Nonepidermal members of the keratin multigene family: cDNA sequences and in situ localization of the mRNAs

1986 • 64 citations

Amino acid sequence of the carboxy-terminal part of an acidic type I cytokeratin of molecular weight 51 000 from Xenopus laevis epidermis as predicted from the cDNA sequence.

1984 • 63 citations

Developmentally regulated cytokeratin gene in Xenopus laevis.

1985 • 62 citations

Cytokeratin expression in simple epithelia

1986 • 60 citations

Cytokeratin expression in simple epithelia

1986 • 52 citations

Complete sequence of a bovine type I cytokeratin gene: conserved and variable intron positions in genes of polypeptides of the same cytokeratin subfamily.

1985 • 52 citations

Sequence of the human 40-kDa keratin reveals an unusual structure with very high sequence identity to the corresponding bovine keratin.

1988 • 49 citations

Sequence and expression of a human type II mesothelial keratin.

1985 • 49 citations

Antigenic interrelationship between the 40‐kilodalton cytokeratin polypeptide and desmoplakins

1986 • 47 citations

Sequence of cDNA coding for human keratin 19

1987 • 46 citations

Light and electron microscopic studies of physical injury to the skin I. Suction

1974 • 41 citations

A rapid antibody assay system for screening hybridoma cultures

1981 • 32 citations

Sequence of a cDNA encoding human keratin No 10 selected according to structural homologies of keratins and their tissue-specific expression

1987 • 17 citations

Biosynthesis of a glycosylated keratin by human keratinocytes

1986 • 14 citations