IL-17 Is Produced by Nickel-Specific T Lymphocytes and Regulates ICAM-1 Expression and Chemokine Production in Human Keratinocytes: Synergistic or Antagonist Effects with IFN-γ and TNF-α

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Human Chemokines: An Update

1997 • 2,235 citations

Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s

1998 • 2,048 citations

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines.

1996 • 1,496 citations

Selective Expression of the Eotaxin Receptor CCR3 by Human T Helper 2 Cells

1997 • 1,073 citations

The Neutrophil-Activating Protein (NAP-1) Is Also Chemotactic for T Lymphocytes

1989 • 1,060 citations

Human IL-17: a novel cytokine derived from T cells.

1995 • 1,014 citations

Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor

1995 • 991 citations

ELAM-1 is an adhesion molecule for skin-homing T cells

1991 • 843 citations

IL-17 Stimulates the Production and Expression of Proinflammatory Cytokines, IL-β and TNF-α, by Human Macrophages

1998 • 810 citations

Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by interferon gamma and is mediated by intercellular adhesion molecule 1 (ICAM-1).

1988 • 680 citations

Human monocyte chemoattractant protein‐1 (MCP‐1) Full‐length cDNA cloning, expression in mitogen‐stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE

1989 • 593 citations

Genomic structure of the human monocyte-derived neutrophil chemotactic factor IL-8.

1989 • 515 citations

Characterization of intercellular adhesion molecule-1 and HLA-DR expression in normal inflamed skin: Modulation by recombinant gamma interferon and tumor necrosis factor

1989 • 505 citations

A human T cell-specific molecule is a member of a new gene family.

1988 • 500 citations

Tumor necrosis factor alpha and interferon gamma synergistically induce interleukin 8 production in a human gastric cancer cell line through acting concurrently on AP-1 and NF-kB-like binding sites of the interleukin 8 gene.

1992 • 450 citations

Synergy between Interferon-γ and Tumor Necrosis Factor-α in Transcriptional Activation Is Mediated by Cooperation between Signal Transducer and Activator of Transcription 1 and Nuclear Factor κB

1997 • 410 citations

T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: interferon gamma-producing (Tc1) effector CD8+ T cells and interleukin (Il) 4/Il-10-producing (Th2) negative regulatory CD4+ T cells.

1996 • 398 citations

Regulation of the production of the RANTES chemokine by endothelial cells. Synergistic induction by IFN-gamma plus TNF-alpha and inhibition by IL-4 and IL-13.

1995 • 318 citations

Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils

1997 • 292 citations

MOLECULAR CHARACTERIZATION OF THE HUMAN INTERLEUKIN (Il)-17 RECEPTOR

1997 • 282 citations

T lymphocyte recruitment by interleukin-8 (IL-8). IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo.

1996 • 271 citations

Marked synergism between tumor necrosis factor-alpha and interferon-gamma in regulation of keratinocyte-derived adhesion molecules and chemotactic factors.

1990 • 261 citations

Human airway smooth muscle cells express and release RANTES in response to T helper 1 cytokines: regulation by T helper 2 cytokines and corticosteroids.

1997 • 242 citations

Nuclear factor-kappa B potently up-regulates the promoter activity of RANTES, a chemokine that blocks HIV infection.

1997 • 238 citations

Induction of hapten-specific tolerance by interleukin 10 in vivo.

1994 • 232 citations

Granulocyte macrophage colony-stimulating factor is overproduced by keratinocytes in atopic dermatitis. Implications for sustained dendritic cell activation in the skin.

1997 • 202 citations

Patients with Allergic Contact Dermatitis to Nickel and Nonallergic Individuals Display Different Nickel-Specific T Cell Responses. Evidence for the Presence of Effector CD8+ and Regulatory CD4+ T Cells

1998 • 192 citations

Accessory cell function of keratinocytes for superantigens. Dependence on lymphocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction.

1993 • 171 citations

Modulation of leucocyte adhesion molecules, a T-cell chemotaxin (IL-8) and a regulatory cytokine (TNF-α) in allergic contact dermatitis (rhus dermatitis)

1991 • 166 citations

Keratinocyte-Derived Monocyte Chemoattractant Protein 1 (MCP-1): Analysis in a Transgenic Model Demonstrates MCP-1 Can Recruit Dendritic and Langerhans Cells to Skin

1995 • 161 citations

The delayed-type hypersensitivity reaction is dependent on IL-8. Inhibition of a tuberculin skin reaction by an anti-IL-8 monoclonal antibody.

1995 • 119 citations

Interferon-γ-Stimulated Human Keratinocytes Express the Genes Necessary for the Production of Peptide-Loaded MHC Class II Molecules

1998 • 99 citations

CD40 ligation of human keratinocytes inhibits their proliferation and induces their differentiation.

1997 • 92 citations

Epidermal and Oral Keratinocytes Are Induced to Produce RANTES and IL-8 by Cytokine Stimulation

1996 • 91 citations

Characterization of epitopes recognized by hapten-specific CD4+ T cells.

1995 • 80 citations

Regulation of human T lymphocyte chemotaxis in vitro by T cell-derived cytokines IL-2, IFN-gamma, IL-4, IL-10, and IL-13.

1995 • 80 citations

Recombinant human growth-regulated oncogene-alpha induces T lymphocyte chemotaxis. A process regulated via IL-8 receptors by IFN-gamma, TNF-alpha, IL-4, IL-10, and IL-13.

1995 • 71 citations

Cytokine Networks in the Skin.

1995 • 56 citations

The interleukin‐8 receptor B and CXC chemokines can mediate transendothelial migration of human skin homing T cells

1996 • 50 citations

Non-specifically activated human peripheral blood mononuclear cells are cytotoxic for human keratinocytes in vitro.

1989 • 44 citations

Epidermis and Lymphocyte Interactions During an Allergic Patch Test Reaction. Increased Activity of ETAF/IL-1, epidermal derived lymphocyte reactivity in persons with type IV allergy

1988 • 32 citations

Keratinocyte expression of intercellular adhesion molecule 1 (ICAM‐1) correlated with infiltration of lymphocyte function associated antigen 1 (LFA‐1) positive cells in evolving allergic contact dermatitis reactions

1991 • 30 citations

Contact Sensitivity as a Model for T-Cell Activation in Skin.

1995 • 21 citations

Cell Populations in Experimental Contact Dermatitis

1977 • 11 citations

Keratinocytes-Associated Chemokines and Enzymatically Quiescent Heparanase Induce the Binding of Resting CD4+ T Cells

1996 • 8 citations

sICAM-1, sE-selectin and sVCAM-1 are constitutively present in human skin lymph and increased in allergic contact dermatitis

1997 • 6 citations