The Role of Dominant Rhodopsin Mutations in Drosophila Retinal Degeneration

Handbook of genetics

1975 • 791 citations

The Drosophila ninaE gene encodes an opsin

1985 • 545 citations

Constitutively active mutants of rhodopsin

1992 • 513 citations

Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa.

1991 • 492 citations

Isolation and structure of a rhodopsin gene from D. melanogaster

1985 • 481 citations

Mutations within the Rhodopsin Gene in Patients with Autosomal Dominant Retinitis Pigmentosa

1990 • 478 citations

A rhodopsin gene mutation responsible for autosomal dominant retinitis pigmentosa results in a protein that is defective in localization to the photoreceptor outer segment

1994 • 338 citations

The cyclophilin homolog ninaA is required in the secretory pathway

1991 • 330 citations

Rhodopsin mutations responsible for autosomal dominant retinitis pigmentosa. Clustering of functional classes along the polypeptide chain.

1993 • 327 citations

Abnormal Electroretinograms in Visual Mutants of Drosophila

1969 • 258 citations

Defective intracellular transport is the molecular basis of rhodopsin-dependent dominant retinal degeneration.

1995 • 239 citations

Nonphototactic Mutants in a Study of Vision of Drosophila

1969 • 207 citations

Drosophila retinal degeneration C (rdgC) encodes a novel serine/threonine protein phosphatase

1992 • 158 citations

Regulatory arrestin cycle secures the fidelity and maintenance of the fly photoreceptor cell.

1993 • 150 citations

Retinal degeneration caused by dominant rhodopsin mutations in Drosophila

1995 • 135 citations

Degeneration of photoreceptors in rhodopsin mutants of Drosophila

1992 • 98 citations

Maturation of major drosophila rhodopsin, ninaE, requires chromophore 3-hydroxyretinal

1993 • 90 citations

Morphological Defects in ora^jk84Photoreceptors Caused by Mutation in R1-6 Opsin Gene of Drosophila

1989 • 88 citations

Electrophysiological study of Drosophila rhodopsin mutants.

1986 • 87 citations

A labile, Ca2+-dependent cytoskeleton in rhabdomeral microvilli of blowflies

1982 • 76 citations

Rhabdomere turnover and rhodopsin cycle: maintenance of retinula cells inDrosophila melanogaster

1988 • 65 citations

Drosophila locus with gene-dosage effects on rhodopsin

1983 • 62 citations

Drosophila mutants with reduced rhodopsin content.

1983 • 61 citations

Mutations Affecting the Vision of Drosophila melanogaster

1975 • 60 citations

Requirement of N-linked glycosylation site inDrosophilarhodopsin

1992 • 57 citations

Ultrastructure of the retina ofDrosophila melanogaster: The mutantora(outer rhabdomeres absent) and its inhibition of degeneration inrdgB(retinal degeneration-B)

1987 • 55 citations

Freeze-fracture study of the Drosophila photoreceptor membrane: mutations affecting membrane particle density.

1982 • 55 citations

Isolation of adaptation mechanisms and photopigment spectra by vitamin A deprivation inDrosophila

1976 • 53 citations

Studies of theDrosophila norpA phototransduction mutant

1987 • 46 citations

Molecular defects in Drosophila rhodopsin mutants

1989 • 46 citations

Opsin maturation and targeting to rhabdomeral photoreceptor membranes requires the retinal chromophore.

1994 • 44 citations

The Biology of photoreception

1983 • 43 citations

Photoreceptor Maintenance and Degeneration in theNorpa(No Receptor Potential-A) Mutant ofDrosophila Melanogaster

1989 • 34 citations

Ultrastructure of the compound eye and first optic neuropile of the photoreceptor mutant ora JK84 of Drosophila

1983 • 24 citations