The neurobiology of stress ulcers
Data up to Jan 2025
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Abstract
References (449)
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Effects of punishing the coping response (conflict) on stress pathology in rats.
1971 • 181 citations
20 YEARS OF HOSPITAL ADMISSIONS FOR PEPTIC ULCER IN ENGLAND AND WALES
1981 • 173 citations
Gastric motility is a major factor in cold restraint-induced lesion formation in rats
1986 • 168 citations
Time-related differences in noradrenaline turnover in rat brain regions by stress
1982 • 167 citations
Stress ulcer susceptibility and depression in Wistar Kyoto (WKY) rats
1989 • 162 citations
Sex-dependent effects of inescapable shock administration on shuttlebox-escape performance and elevated plus-maze behavior
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1976 • 143 citations
Psychological stress enhances noradrenaline turnover in specific brain regions in rats
1982 • 142 citations
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1957 • 142 citations
Hippocampal pathway to the amygdala and stress ulcer development
1990 • 137 citations
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1956 • 137 citations
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MPTP: A neurotoxin producing a parkinsonian syndrome
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Corticotropin-releasing factor (CRF): mechanism to elevate mean arterial pressure and heart rate
1983 • 133 citations
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1969 • 133 citations
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1961 • 132 citations
Effects of early experience and differential housing on behavior and susceptibility to gastric erosions in the rat.
1965 • 131 citations
Hypothermic and antipyretic effects of centrally administered ACTH (1–24) and α-melanotropin
1981 • 130 citations
Life events stress and psychosocial factors in men with peptic ulcer disease
1986 • 129 citations
MIF-I's differential actions as an opiate antagonist
1979 • 121 citations
Brain Histamine: Rapid Apparent Turnover Altered by Restraint and Cold Stress
1971 • 120 citations
Microcirculatory and mast cell changes in restraint-induced gastric ulcer
1966 • 118 citations
DOPAMINE DISORDER IN DUODENAL ULCERATION
1979 • 117 citations
Physiological Damage under Emotional Stress as a Function of Early Experience
1954 • 117 citations
Sex differences in emotional and cognitive behaviour in mammals including man: Adaptive and neural bases
1971 • 116 citations
Duodenal ulcer in black populations in Africa south of the Sahara.
1975 • 111 citations
The opioid/nonopioid nature of stress-induced analgesia and learned helplessness.
1983 • 110 citations
Brain norepinephrine metabolism and shock-induced fighting behavior in rats: differential effects of shock and fighting on the neurochemical response to a common footshock stimulus.
1974 • 110 citations
Behavior in the open field, Lashley III maze, shuttle-box, and Sidman avoidance as a function of strain, sex, and age.
1970 • 107 citations
The influence of food consumption and running activity on the activity-stress ulcer in the rat
1975 • 107 citations
Sex Differences in Peptic Ulcer Disease
1985 • 104 citations
Dopamine in gastrointestinal disease
1990 • 103 citations
Effects of Prenatal Maternal Handling and Differential Housing on Offspring Emotionality, Plasma Corticosterone Levels, and Susceptibility to Gastric Erosions
1968 • 103 citations
Development of gastric ulcers in rats following stress termination.
1974 • 102 citations
Activity and food-restriction effects on gastric glandular lesions in the rat: The activity-stress ulcer
1973 • 101 citations
Peptic ulcer in India and Bangladesh.
1979 • 99 citations
Regional responses of rat brain noradrenergic neurones to acute intense stress
1981 • 99 citations
Predictable and unpredictable shock: Behavioral measures of aversion and physiological measures of stress.
1984 • 97 citations
Gender differences in open‐field behavior as a function of age
1980 • 97 citations
“Behavioral despair” test predicts stress ulcer in WKY rats
1989 • 94 citations
Cardiovascular changes during arousal elicited by stimulation of amygdala, hypothalamus and locus coeruleus
1981 • 94 citations
Role of Gastric Motility in Development of Stress-Induced Gastric Lesions of Rats
1978 • 93 citations
THE ASSOCIATION OF GASTRO‐DUODENAL ULCERATION AND PARKINSON'S DISEASE
1965 • 87 citations
Regional rat brain noradrenaline turnover in response to restraint stress
1983 • 86 citations
Use of the restrained rat technique for study of the antiulcer effect of drugs
1960 • 84 citations
An experimental method of producing gastric ulcers.
1956 • 83 citations
Principles of Mammalian Aging
1972 • 83 citations
A study of the amygdaloid defence reaction showing the value of Althesin anaesthesia in studies of the functions of the fore-brain in cats
1981 • 82 citations
Central noradrenergic inhibition of gastric mucosal blood flow and acid secretion in rats
1977 • 82 citations
Gastric erosions induced by intracisternal thyrotropin-releasing hormone (TRH) in rats
1985 • 81 citations
Restraint ulcer: History, current research and future implications
1980 • 80 citations
The pathophysiology of peptic ulcer disease
1985 • 80 citations
An experimental investigation of the role of psychological factors in the production of gastric ulcers in rats.
1956 • 80 citations
Prevention of stress-induced gastric ulcers by dopamine agonists in the rat
1984 • 79 citations
The effect of centrally administered neuropeptides on the development of stress‐induced gastric ulcers in rats
1983 • 76 citations
The effect of group vs. individual housing on behaviour and physiological responses to stress in the albino rat
1960 • 76 citations
HEREDITARY FACTORS IN PEPTIC ULCER
1949 • 75 citations
Adulthood and Aging: An Interdisciplinary Developmental View
1974 • 74 citations
Age at Maternal Separation and Gastric Erosion Susceptibility in the Rat*
1975 • 73 citations
Thyrotropin-releasing hormone
1983 • 72 citations
Some Experimental Observations on Gastro intestinal Lesions in Behaviorally Conditioned Monkeys
1958 • 72 citations
Increased sympathetic activity in the pathogenesis of restraint ulcer in rats.
1973 • 71 citations
Stress, Health, and the Social Environment
1978 • 71 citations
Neuroendocrine mechanisms of stress ulceration: Focus on thyrotropin-releasing hormone (TRH)
1986 • 69 citations
Ulcer disease: New aspects of pathogenesis and pharmacology
1990 • 66 citations
The bed nucleus of the stria terminalis and immobilization-stress
1984 • 66 citations
Prevention by bombesin of cold-restraint stress induced hemorrhagic lesions in rats
1979 • 65 citations
Mepirizole-induced duodenal ulcers in rats and their pathogenesis
1982 • 65 citations
The central amygdala and immobilization stress-induced gastric pathology in rats: neurotensin and dopamine
1987 • 64 citations
The centromedial amygdala and gastric pathology in rats
1980 • 64 citations
Food deprivation, shock stress and stomach lesions in the rat
1973 • 63 citations
A Model for Life Changes and Illness Research
1974 • 63 citations
Gastric Erosions in the Rat: Effects of Immobilization at Different Points in the Activity Cycle
1964 • 62 citations
Gastrointestinal Disease: Pathophysiology—Diagnosis—Management
1974 • 61 citations
Society, Stress and Disease.
1979 • 61 citations
Activation of dopamine synthesis in mesolimbic dopamine neurons by immobilization stress in the rat
1984 • 60 citations
Human Gastric Function: An Experimental Study of a Man and His Stomach
1944 • 59 citations
Selective breeding for development of stomach lesions following stress in the rat.
1959 • 59 citations
Recovery of stress-induced increases in noradrenaline turnover is delayed in specific brain regions of old rats
1984 • 58 citations
Neurophysiology of limbic system pathways in the rat: Projections from the amygdala to the entorhinal cortex
1986 • 58 citations
Intracisternal injection of CRF antagonist blocks surgical stress-induced inhibition of gastric secretion in the rat
1988 • 58 citations
Changes in Dopamine, Noradrenaline and Adrenaline in Specific Septal and Preoptic Nuclei after Acute Immobilization Stress
1982 • 57 citations
Cytoprotective effect of centrally administered neurotensin on stress-induced gastric ulcers
1982 • 56 citations
Intracerebroventricular neuropeptide Y protects against stress-induced gastric erosion in the rat
1987 • 56 citations
Psychological studies of stress ulcer in the rat
1980 • 56 citations
Brain Regulation of Gastric Acid Secretion by Peptides
1990 • 55 citations
Body orientation, food deprivation and potentiation of restraint induced gastric lesions.
1977 • 55 citations
Pathophysiology of Peptic Ulcer
1964 • 55 citations
Anti-ulcer activity of calcitonin gene-related peptide in rats
1987 • 54 citations
Gastric Mucus Content During Development of Ulcers in Fasting Rats
1963 • 54 citations
Social factors affecting emotionality and resistance to disease in animals: I. Age of separation from the mother and susceptibility to gastric ulcers in the rat.
1960 • 54 citations
Effects of age and stress on regional noradrenaline metabolism in the rat brain
1982 • 53 citations
Elevation of activity level in the rat following transition from ad libitum to restricted feeding.
1953 • 53 citations
Effects of exogenous administration of female sex hormones on gastric secretion and ulcer formation in the rat
1984 • 52 citations
Amygdaloid complex modulates neurotransmission from the entorhinal cortex to the dentate gyrus of the rat
1984 • 52 citations
A role for dopamine as an endogenous protective factor in the rat stomach
1989 • 52 citations
Psychosomatic Disorders. A Psychophysiological Approach to Etiology and Treatment.
1982 • 51 citations
The amydala and restraint ulcers in rats.
1980 • 51 citations
Activity-stress ulcer in the rat: Frequency and chronicity
1976 • 50 citations
Activity of selective dopamine DA1 and DA2 agonists and antagonists on experimental gastric lesions and gastric acid secretion.
1989 • 50 citations
Early environmental enrichment and mouse behavior.
1970 • 50 citations
Gastric mucosal ulceration associated with electrochemical stimulation of the limbic brain
1980 • 50 citations
Facilitation and inhibition of gastric pathology after lesions in the amygdala of rats
1980 • 50 citations
PITUITARY-ADRENAL ACTIVATION IN RATS WITH MEDIAL BASAL HYPOTHALAMIC ISLANDS
1970 • 49 citations
Marked enhancement of noradrenaline turnover in extensive brain regions after activity-stress in rats
1982 • 49 citations
Experimental Peptic Ulcer
1968 • 48 citations
Stress-related mucosal damage: An overview
1987 • 48 citations
Cerebral influence on gastric motility in the cat.
1952 • 48 citations
Recent studies of the central nucleus of the amygdala and stress ulcers
1988 • 48 citations
Opiate mechanisms in the central amygdala and gastric stress pathology in rats
1988 • 47 citations
Effect of Chronic Fear on the Gastric Secretion of HCl in Dogs
1949 • 47 citations
Stress ulcer and open-field behavior of spontaneously hypertensive, normotensive, and Wistar rats
1989 • 47 citations
The Etiology of Experimental Gastric Ulceration
1957 • 46 citations
Effect of electrical stimulation of the limbic system of brain (visceral brain) on gastric secretory activity and ulceration.
1957 • 45 citations
Neuropeptides and stress
1989 • 44 citations
Biochemical changes in tissue catecholamines and serotonin in duodenal ulceration caused by cysteamine or propionitrile in the rat.
1987 • 44 citations
Kindling in the amygdala and susceptibility to stress ulcers
1985 • 44 citations
Serial stressors: Prior exposure to a stressor modulates its later effectiveness on gastric ulceration and corticosterone release
1986 • 43 citations
Body temperature and the activity-stress ulcer in the rat
1977 • 43 citations
Mesencephalic Dopaminergic Neurons: Role in the General Economy of the Brain
1988 • 43 citations
Predisposition to Gastric Erosions in the Rat: Behavioral and Nutritional Effects of Early Maternal Separation
1978 • 43 citations
Effect of aging on gastric acid secretion, serum gastrin, and antral gastrin content in rats
1988 • 43 citations
STUDY OF CENTRAL NEUROTRANSMITTERS IN STRESS‐INDUCED GASTRIC ULCERATION IN ALBINO RATS
1980 • 42 citations
Strain, age, but not gender, influence ulcer severity induced by water-restraint stress
1989 • 42 citations
Behavioural correlates of genetically enhanced susceptibility to stomach lesion development
1961 • 42 citations
Gastric hypersecretion by intracisteral TRH: Dissociation from hypophysiotropic activity and role of central catecholamine
1985 • 42 citations
Central dopamine systems and gastric stress pathology in rats
1988 • 41 citations
Blood Pepsinogen and Gastric Erosions in the Rat
1960 • 41 citations
Central and peripheral adrenergic mechanisms regulating gastric secretion in the rat.
1977 • 41 citations
Brain corticotropin-releasing factor acts as inhibitor of stress-induced gastric erosion in rats
1990 • 41 citations
Changing demographics of peptic ulcer disease
1985 • 40 citations
Unit-activity in the central amygdalar nucleus of rats in response to immobilization—stress
1983 • 40 citations
Improved restraint-technique for producing stress and cardiac necrosis in rats
1959 • 40 citations
Predictable vs. unpredictable shock: Preference behavior and stomach ulceration
1972 • 40 citations
Stress and ulcer etiology in the rat
1976 • 40 citations
Sex Differences and Incidence of Activity-Stress Ulcers in the Rat
1978 • 40 citations
Clinical and Social Problems of Peptic Ulcer
1957 • 39 citations
Intrahypothalamic corticotropin-releasing factor elevates gastric bicarbonate and inhibits stress ulcers in rats
1990 • 39 citations
The hypothalamus-amygdala axis and experimental gastric ulcers
1979 • 39 citations
The effects of centrally administered neuropeptides on the development of gastric lesions in the rat
1985 • 39 citations
Conditioning and avoidance responding effects on gastric secretion in the rat with chronic fistula.
1972 • 38 citations
Lesions in aged germfree Wistar rats.
1970 • 38 citations
The role of the adrenal gland in cytoprotection against stress‐induced gastric ulcers in rats
1984 • 38 citations
Effects of cimetidine on stress ulcer and gastric acid secretion in the rat
1978 • 38 citations
Gastric lesions secondary to long-distance running
1990 • 38 citations
Strain Differences in Activity, Emotionality, Body Weight and Susceptibility to Stress Induced Stomach Lesions
1962 • 38 citations
Early weaning predisposes rats to exacerbated activity-stress ulcer formation
1985 • 37 citations
Ulcer Disease: New Aspects of Pathogenesis and Pharmacology
1989 • 37 citations
The amygdala and forced immobilization of rats
1985 • 37 citations
Radiation Resistance with Age in Normal and Irradiated Populations of Mice
1965 • 37 citations
Amygdaloid lesions attenuate neurogenic gastric mucosal erosions but do not alter gastric secretory changes induced by intracisternal bombesin
1986 • 37 citations
Effects of intra-amygdalar dopamine agonists and antagonists on gastric stress lesions in rats
1988 • 37 citations
Early weaning effects on voluntary ethanol consumption and stress responsivity in rats
1987 • 36 citations
Chronic alterations in jejunal myoelectric activity in rats due to MPTP
1987 • 36 citations
Corticotropin-releasing factor acts centrally to suppress stimulated gastric contractility in the rat
1988 • 36 citations
Dopamine receptors in human gastrointestinal mucosa
1987 • 36 citations
Inhibition of gastric functions by stimulation of the rat locus coeruleus
1981 • 36 citations
Inhibition of gastric acid secretion by immunoneutralization of endogenous brain thyrotropin-releasing hormone
1987 • 35 citations
Microscopic examination of the activity-stress ulcer in the rat
1978 • 35 citations
Morphologic changes in gastric mucosa of aging rats
1989 • 35 citations
Sex and strain differences in leverpress shock escape behavior
1976 • 35 citations
Enkephalin-dopamine interactions in the central amygdalar nucleus during gastric stress ulcer formation in rats
1990 • 34 citations
Technique and Strain Comparisons in Stress Ulcer
1990 • 34 citations
Hippocampal influence on amygdala unit activity in awake squirrel monkeys
1980 • 34 citations
Pathways mediating CRF-induced inhibition of gastric acid secretion in rats
1989 • 34 citations
Role of acetylcholine, histamine and gastrin in the acid response to intracisternal injection of TRH analog, RX 77368, in the rat
1990 • 34 citations
Stress ulcer in normotensive and spontaneously hypertensive rats
1986 • 34 citations
Plasma Pepsinogen Level as a Predictor of Susceptibility to Gastric Erosions in the Rat
1963 • 34 citations
Hypothalamic and Amygdaloid Influence on Gastric Motility in Dogs
1966 • 34 citations
Protective Effect of Pepto-Bismol Liquid on the Gastric Mucosa of Rats
1975 • 34 citations
Attenuation of shock-induced ulcers after lesions in the medial amygdala☆
1981 • 34 citations
Thyrotropin-releasing hormone: medullary site of action to induce gastric ulcers and stimulate acid secretion
1988 • 33 citations
Production, by Restraint, of Gastric Ulcers and of Hydrothorax in the Rat
1966 • 33 citations
Interaction of environmental enrichment and genotype.
1972 • 33 citations
EFFECTS OF β‐ADRENOCEPTOR DRUG STIMULATION ON VARIOUS MODELS OF GASTRIC ULCER IN RATS
1982 • 33 citations
Granule cell potentials in the dentate gyrus of the hippocampus: Coping behavior and stress ulcers in rats
1990 • 32 citations
The ulcerogenic effect of a rest period after exposure to water-restraint stress in rats
1986 • 32 citations
Conflict duration, feeding schedule, and strain differences in conflict-induced gastric ulcers
1972 • 32 citations
Effects of dopamine agonists and antagonists on gastric acid secretion and stress responses in rats
1987 • 32 citations
Safety signals can mimic responses in reducing the ulcerogenic effects of prior shock
1985 • 32 citations
Social factors affecting emotionality and resistance to disease in animals: III. Early weaning and susceptibility to gastric ulcers in the rat. A control for nutritional factors.
1962 • 32 citations
Dopamine and gastroprotection
1991 • 32 citations
Involvement of brain dopamine systems on neurotensin-induced protection against stress gastric lesions
1986 • 32 citations
Endoscopic and Clinical Findings in First-Degree Relatives of Duodenal Ulcer Patients and Control Subjects
1982 • 31 citations
GASTRIC ACIDITY BEFORE AND AFTER OPERATIVE PROCEDURE WITH SPECIAL REFERENCE TO THE ROLE OF THE PYLORUS AND ANTRUM*
1940 • 31 citations
Activity-stress ulcer in the rat, hamster, gerbil and guinea pig
1976 • 31 citations
Effects of neuropeptides on gastric acid and duodenal bicarbonate secretions in freely moving rats
1989 • 31 citations
The Changing Face of Peptic Ulcer in the Elderly
1976 • 31 citations
The effects of prenatal injections of adrenalin chloride and d- amphetamine sulfate on subsequent emotionality and ulcer-proneness of offspring
1965 • 31 citations
Electrophysiological activity in the central nucleus of the amygdala, emotionality and stress ulcers in rats.
1988 • 31 citations
Effects of chemical stimulation of the hypothalamus upon gastric secretion
1973 • 30 citations
Personality Pattern of Patients with Chronic Gastric Ulcer
1977 • 30 citations
Advances in experimental ulcer
1981 • 30 citations
Vertical Transmission of Acquired Ulcer Susceptibility in the Rat
1980 • 30 citations
Cold-restraint induced gastric lesions in normotensive and spontaneously hypertensive rats
1981 • 30 citations
AMYGDALA AND OTHER RELATED LIMBIC STRUCTURES; EXPERIMENTAL STUDIES ON THE ANATOMY AND FUNCTION. II. FUNCTIONAL EXPERIMENTS.
1964 • 30 citations
Opposing central and peripheral actions of brain-gut peptides: a basis for regulation of gastric function.
1985 • 30 citations
Role of brain neurotransmitters on neurotensin-induced gastric cytoprotection
1985 • 30 citations
Daily feeding schedule and housing on incidence of activity-stress ulcer
1985 • 29 citations
Experimental psychosomatic disease states in monkeys
1964 • 29 citations
Interactions of thyrotropin-releasing hormone (TRH) with neurotensin and dopamine in the central nucleus of the amygdala during stress ulcer formation in rats
1988 • 29 citations
Nutrition, Aging, and Health.
1987 • 29 citations
Gastric secretory response of the unrestrained cat following electrical stimulation of the hypothalamus, amygdala, and basal ganglia
1967 • 29 citations
Effect of central noradrenaline depletion on corticosterone levels and gastric ulcerations in rats
1986 • 28 citations
Neurohumoral pathways mediating stress-induced inhibition of gastric acid secretion in rats
1990 • 28 citations
The effects of perinatal diazepam exposure on stress-induced activation of the mesotelencephalic dopamine system
1989 • 27 citations
The Prevention and Management of Stress Ulcers
1980 • 27 citations
Strain and sex differences in ulceration in the rat.
1962 • 27 citations
Role of the autonomic nervous system in the cytoprotective effect of neurotensin against gastric stress ulcers in rats
1985 • 27 citations
Instrumental control and ulceration in rats.
1970 • 26 citations
Effect of dopamine-related drugs on duodenal ulcer induced by cysteamine or propionitrile: prevention and aggravation may not be mediated by gastrointestinal secretory changes in the rat.
1987 • 26 citations
Increased dopamine receptor binding in duodenal mucosa of duodenal ulcer patients
1989 • 26 citations
Thyroid Hormones Modulate Thyrotropin-Releasing Hormone Biosynthesis in Tissues Outside the Hypothalamic-Pituitary Axis of Male Rats*
1989 • 26 citations
Gastric Lesions in Food-Restricted Young Rats
1972 • 26 citations
The effect of intracisternally administered bombesin on cysteamine-induced duodenal ulcers in rats
1982 • 26 citations
Early handling and group housing: Effect on development and response to stress in the rat
1959 • 26 citations
Noradrenergic mechanisms in the central amygdalar nucleus and gastric stress ulcer formation in rats
1990 • 26 citations
The Effect of Chronic Restraint Stress on Gastric Ulceration in the Rat
1964 • 25 citations
Shock predictability and gastric secretion in the chronic gastric fistula rat
1973 • 25 citations
l-Deprenyl attenuates stress ulcer formation in rats
1986 • 25 citations
Prior stress and susceptibility to stress ulcer
1986 • 25 citations
Neurobiology of brain?gut interactions
1989 • 24 citations
The effects of destruction on noradrenergic ascending ventral bundles and tetrabenazine on formation of stress-induced gastric ulcer
1977 • 24 citations
Juvenile and adult footshock stress modulate later adult gastric pathophysiological reactions to restraint stresses in rats.
1991 • 24 citations
Interactions amongst factors which influence severity of gastric ulceration in rats
1986 • 24 citations
The Peptidergic Brain-Gut Axis: Influence on Gastric Ulcer Formation
1987 • 24 citations
Effects of divided feeding on activity-stress ulcer and the thymus weight in the rat
1981 • 23 citations
Selective noradrenaline depletion markedly alters stress responses in rats
1985 • 23 citations
Dopamine and Dopamine Receptors in the Gut: Their Possible Role in Duodenal Ulceration
1982 • 23 citations
EFFECTS OF THE AMOUNT OF REQUIRED COPING RESPONSE TASKS ON GASTROINTESTINAL LESIONS IN RATS
1975 • 23 citations
Proactive Actions of Psychological Stress on Gastric Ulceration in Rats—Real Psychobiologya
1990 • 23 citations
Effects of vasopressin deficiency, age, and stress on stomach ulcer induction in rats
1985 • 23 citations
Production of gastric lesions in rats by combined cold and electrostress
1967 • 23 citations
Influence of thyroid states on stress gastric ulcer formation
1988 • 23 citations
Effects of prenatal caffeine administration on offspring mortality, open-field behavior and adult gastric ulcer susceptibility.
1985 • 23 citations
Stress-responsive neuromodulators
1988 • 23 citations
Effects of intra-amygdalar Thyrotropin Releasing Hormone (TRH) and its antagonism by atropine and benzodiazepines during stress ulcer formation in rats
1990 • 23 citations
Gastric secretion and activity-stress lesions in the rat.
1977 • 22 citations
Early life events and peptic ulcer susceptibility: An experimental model
1980 • 22 citations
Studies on the interaction between ICV effects of CRF and CNS noradrenaline depletion
1990 • 22 citations
The GABA/benzodiazepine receptor complex in the central amygdalar nucleus and stress ulcers in rats
1989 • 22 citations
The Role of Stress in Peptic Ulcer Disease
1979 • 22 citations
The Behavior of Normal and Stomach Lesion Susceptible Rats in Several Learning Situations
1963 • 22 citations
Differential effect of changing central and peripheral catecholamine levels in cysteamine-induced duodenal ulcer in the rat.
1981 • 22 citations
Stress and ulceration in the glandular and nonglandular portions of the rat's stomach.
1973 • 22 citations
Prepared responses and gastric lesions in rats
1980 • 21 citations
Evidence for a role of brain thyrotropin-releasing hormone (TRH) on stress gastric lesion formation in rats
1990 • 21 citations
Activity Wheel Stress: Changes in Brain Norepinephrine Turnover and the Occurrence of Gastric Lesions
1984 • 21 citations
THE PRODUCTION OF ULCER OF THE STOMACH IN THE RAT.
1913 • 21 citations
Metabolic influence of the hippocampus on hypothalamus, preoptic and basal forebrain is exerted through amygdalofugal pathways
1984 • 21 citations
Stomach ulceration and emotionality in selected strains of rats
1965 • 21 citations
Effects of unpredictability of shock on incidence of gastric lesions and heart rate in immobilized rats
1972 • 21 citations
Effects of acute and chronic stress situations on stomach acidity in rats.
1971 • 20 citations
Production of gastric ulcers in the unrestrained rat
1973 • 20 citations
Prenatal maternal stress: Differential effects upon male and female offspring responses to restraint stress as adults
1984 • 20 citations
Quality of poststressor rest influences the ulcerative process.
1987 • 20 citations
Neurotensin and the Mesocorticolimbic Dopamine Systema
1988 • 20 citations
Poststress effects of danger and safety signals on gastric ulceration in rats.
1989 • 20 citations
Duodenal ulceration in Indians and Blacks in Durban.
1979 • 20 citations
Age differences and stress ulcer in the rat
1979 • 20 citations
Plasma corticosterone and restraint induced gastric pathology: Age-related differences after administration of corticotropin releasing factor
1989 • 19 citations
Age and Susceptibility to Gastric Ulceration in Male and Female Rats
1966 • 19 citations
Imipramine prevents stress gastric glandular lesions in rats
1989 • 19 citations
SOME SURGICAL ASPECTS OF FAULTY NUTRITION.
1931 • 19 citations
Relationship between running activity rhythm and the development of activity-stress ulcer in rats.
1990 • 19 citations
Synaptic efficacy in the entorhinal-dentate pathway and stress ulcers in rats
1989 • 18 citations
Histopathology and pathogenesis of behaviorally induced gastric lesions in rats.
1973 • 18 citations
The responding-rest ratio in the production of gastric ulcers in the rat
1963 • 18 citations
Hippocampal deafferentation and deefferentation and gastric pathology in rats
1981 • 18 citations
SPONTANEOUS PEPTIC ULCERS IN MICE
1967 • 18 citations
Intrahypothalamic microinjection of calcitonin prevents stress-induced gastric lesions in rats
1988 • 18 citations
Post-stress development and healing of supine-restraint induced stomach lesions in the rat
1982 • 18 citations
Starvation ulcer in the mouse
1960 • 17 citations
Gastric pathologic and biochemical changes induced by starvation of weanling rats
1966 • 17 citations
Effect of prostaglandin synthesis inhibitors on neurotensin and sodium salicylate-induced gastric cytoprotection in rats
1983 • 17 citations
Production of duodenal ulcers in the rat by administration of digitoxin
1974 • 17 citations
The Role of Brain Peptides in the Pathogenesis of Experimental Stress Gastric Ulcersa
1990 • 17 citations
The effect of conflict and shock stress on stomach ulceration in the rat
1962 • 17 citations
Duodenal ulcers are associated with a depletion of duodenal calcitonin gene-related peptide-like immunoreactivity in rats
1989 • 16 citations
Potentiation of inputs from the posterolateral amygdala to the dentate gyrus and resistance to stress ulcers formation in rats
1990 • 16 citations
Starvation, Glucose, and Stress Ulcers in the Rat
1974 • 16 citations
Evidence of “cross-stressor” - induced adaptive gastric cytoprotection
1987 • 16 citations
Somatic response as a function of no signal, random signal, or signaled shock with variable or constant durations of shock
1971 • 16 citations
Effects of coping behavior on gastric lesions in rats as a function of the complexity of coping tasks☆
1983 • 16 citations
The effect of premature weaning on the sensitivity of rats to experimental erosions of the gastric mucosa.
1967 • 16 citations
Mediation of Gastrointestinal Stress Responses by Corticotropin‐Releasing Factor
1990 • 16 citations
Study of cold + restraint stress gastric lesions in spontaneously hypertensive, Wistar and Sprague-Dawley rats
1973 • 16 citations
The experimental production and treatment of peptic ulcers
1949 • 15 citations
Early experience and adaptation to stress.
1966 • 15 citations
Stress-Induced Gastric Lesions in Mice
1965 • 14 citations
Role of gastric acid in restraint-induced ulceration in the rat
1976 • 14 citations
Effect of tyrosine administration on duodenal ulcer induced by cysteamine in the rat.
1987 • 14 citations
PREVENTIVE EFFECT OF FUSARIC ACID, A DOPAMINE β-HYDROXYLASE INHIBITOR, ON THE GASTRIC ULCERATION INDUCED BY WATER-IMMERSION STRESS IN RATS
1973 • 14 citations
Age, weight, and social effects on ulceration rate in rats.
1966 • 14 citations
Stress, Coping Behavior and Resistance to Disease
1982 • 14 citations
Restricted feeding and incidence of activity-stress ulcers in the rat
1978 • 14 citations
Effect of patterns of aversive and appetitive conditioned stimuli on the incidence of gastric lesions in the immobilized rat.
1969 • 13 citations
Aging Research (II): Pacemakers for Aging?
1974 • 13 citations
THE INFLUENCE OF SEX HORMONES ON EXPERIMENTALLY PRODUCED GASTRIC ULCER IN RATS
1955 • 13 citations
The effects of buspirone, a selective anxiolytic, on stress ulcer formation in rats
1988 • 13 citations
The effects of housing and preshock on activity-stress ulcer
1985 • 13 citations
Vendor differences in starvation-induced gastric ulceration
1977 • 13 citations
Free-operant avoidance behavior and gastric ulceration in rats☆☆☆
1973 • 13 citations
Effect of age, food deprivation and stress on gastric erosions in the rat
1979 • 13 citations
Influence of Aging on Stress Ulcer Formation in Rats
1989 • 13 citations
The Effect of Ambient Temperature on Restraint Ulcer in the Rat
1970 • 13 citations
Effect of an anti-acetylcholine drug, methscopolamine bromide, on ulcer formation and gastric mucus
1964 • 13 citations
A central site of dopamine agonist action to modify gastric secretion in the rat
1985 • 13 citations
Stress duration, gastric emptying, and ulcer development in three strains of rats
1977 • 13 citations
Experimental production and control of stomach lesions in the rat
1960 • 12 citations
The experimental production of resistance to stress-induced stomach lesions in the rat
1977 • 12 citations
Experimental stress ulcer and gastric catecholamine contents in spontaneously hypertensive rats
1986 • 12 citations
Differential gastric ulceration in rats receiving shocks on either fixed-time or variable-time schedules.
1987 • 12 citations
Gastric ulcers in swine. A potential model for study of gastric ulcer in man
1968 • 12 citations
Effects of Early Experience and Differential Housing on Susceptibility to Gastric Erosions in Lesion-Susceptible Rats
1970 • 12 citations
The effects of restraint and restraint plus intermittent shock on ulcer formation in Brattleboro rats
1983 • 12 citations
Age, stressors, and psychosomatic disorders
1980 • 11 citations
The Genetics of Peptic Ulcer
1985 • 11 citations
Mesolimbic dopamine mediates gastric mucosal protection by central neurotensin
1991 • 11 citations
Role of Gastric Acid in the Development of Duodenal Ulcers in the Rat
1972 • 11 citations
Effects of naltrexone and signaling inescapable electric shock on nociception and gastric lesions in rats.
1984 • 11 citations
Sex differences in stress-induced gastric ulceration: Effects of castration and ovariectomy
1987 • 11 citations
Dissimilarity of mechanisms for evocation of escape and avoidance responding in dogs
1976 • 11 citations
Differential effects of intracisternal neurotensin and bombesin on stress-and ethanol-induced gastric ulcers
1986 • 11 citations
Pre-stress sensory input as a non-pharmacologic method for controlling restraint-ulcer susceptibility
1965 • 11 citations
Experimental peptic ulceration.
1963 • 10 citations
Activity-stress gastric lesions in the chipmunk (Tamias striatus)
1977 • 10 citations
Involvement of dopamine receptors in experimental ulceration.
1987 • 10 citations
Role of dopaminergic mechanisms in the central amygdalar nucleus in the regulation of stress-induced gastric ulcer formation in rats.
1989 • 10 citations
Age differences in the body temperature response to restraint-cold stress
1989 • 10 citations
Stomach mucosal lesions in stressed rats with and without post-stress rest
1981 • 10 citations
PHYSIOLOGICAL AND BEHAVIORAL CHARACTERISTICS OF RATS SELECTIVELY BRED FOR SUSCEPTIBILITY TO STOMACH LESION DEVELOPMENT.
1963 • 10 citations
Effects of altered brain noradrenaline level on acute stress pathology in rats.
1983 • 10 citations
Effect of hypophysectomy, adrenalectomy, pituitary hormone secretion and gastric acid secretion on neurotensin induced gastric protection against stress gastric lesions
1987 • 10 citations
Reduced fat stores after early weaning: A correlate of vulnerability to stress ulcers
1986 • 10 citations
Experimental production of duodenal ulcers.
1974 • 10 citations
Priming effects of activity-stress ulcer in rats
1982 • 9 citations
Environmental and genetic effects on food-deprivation induced stomach lesions in male rats
1983 • 9 citations
Stress-induced gastric lesions in spontaneously hypertensive rats
1974 • 9 citations
Strain and Sex Differences in Gastric Ulceration in Restrained Rats
1967 • 9 citations
Restraint induced ulceration in rats during estrus and diestrus
1972 • 9 citations
Some metabolic and biochemical alterations during the development of stress ulcers in rats forced to swim.
1983 • 9 citations
Prenatal maternal conditioned fear and subsequent ulcer-proneness in the rat
1967 • 9 citations
Cimetidine and stress ulcer in aged rats
1984 • 9 citations
Administration of thyrotropin-releasing hormone into the central nucleus of the amygdala induces gastric lesions in rats
1990 • 9 citations
Endogenous Serotonin Produces an Inhibitory Tone on Vagally Stimulated Gastric Functiona
1990 • 9 citations
Genetically obese (ob/ob) mice are predisposed to gastric stress ulcers.
1984 • 9 citations
Genetic predisposition to stomach ulceration in emotionally reactive strains of rats
1969 • 9 citations
Heritability of Stress-Ulcer Susceptibility in Rats
1968 • 9 citations
Ulceration of Oral and Gastric Mucosa Produced by Stress in Rats
1969 • 8 citations
Subject emotionality and subsequent pylorus ligation-induced or restraint-induced gastric ulcer
1980 • 8 citations
The Role of the Sympathetic Nervous System in Cysteamine-Induced Gastric Lesions in Rats
1989 • 8 citations
Restraint Ulceration as an Experimental Disease Model
1975 • 8 citations
Stress and common gastrointestinal disorders: A comprehensive approach
1986 • 8 citations
Fear, Stimulus Feedback, and Stressor Controllability
1989 • 8 citations
Conditioned immobility and ulcer development in rats.
1974 • 8 citations
Methylphenidate effects on activity-stress gastric lesions and regional brain noradrenaline metabolism in rats
1985 • 8 citations
Imipramine prevents gastric lesions induced by centrally administered thyrotropin-releasing hormone (TRH) in rats
1990 • 7 citations
Escape deficits following inescapable shock: The role of contextual odor.
1984 • 7 citations
Central Neurotensin Protects the Mucosa by a Prostaglandin‐Mediated Mechanism and Inhibits Gastric Acid Secretion in the Rata
1990 • 7 citations
Gastric mucosal damage induced by lateral hypothalamic lesions in female rats: Influence of age and ovariectomy
1991 • 7 citations
The Role of the Hypothalamic‐Pituitary‐Thyroid Axis in Stress Gastric Ulcers
1990 • 7 citations
Brain acth prevents stress gastric lesions in rats
1990 • 6 citations
Stress and experimental ulcer: Critique of psychological literature.
1978 • 6 citations
Immobilization-produced gastric pathology in wild rats ( Rattus norvegicus )
1972 • 6 citations
Effects of manipulating cholinergic tone upon the activity-stress ulcer
1975 • 6 citations
Reduction of stomach ulceration by hypothalamic stimulation in the unrestrained rat
1976 • 6 citations
Stress Ulceration—Clinical Relevance of Animal and Human Studies
1987 • 5 citations
Effects of scopolamine methylbromide on shock-induced gastric lesions in the unrestrained rat
1974 • 5 citations
The activity-stress ulcer in the hamster
1976 • 5 citations
The Developmental Physiology of the Stomach: Possible Contributions to the Regulatory Disturbances of Duodenal Ulcer Disease
1984 • 5 citations
Duodenal Ulcer, Largely an Urban Disease in Africans in Subtropical Africa
1978 • 5 citations
A Study on Gastric Ulcers Induced by Long-Term Fasting in Rats
1989 • 5 citations
Effect of Ovariectomy and of Estrogen Administration Upon Gastric Ulceration Induced by Cold-Restraint
1969 • 5 citations
Duodenal Ulceration: A Gastroscopic Study
1946 • 5 citations
The Effect of Age and Strain Differences on the Incidence of Restraint-Induced Oral and Gastric Ulcers in Three Strains of Rats
1972 • 4 citations
Influence of Neurotensin on Endogenous Dopamine Release from Explanted Mesoaccumbens Neurons in Vitro: Selective Activation of Somatodendritic Receptor Sitesa
1988 • 4 citations
Gastric Lesions in Rats Selectively Bred for Differential Alcohol Sensitivity
1983 • 4 citations
Les ulcères gastriques de dénutrition
1964 • 4 citations
Paradoxical DSP-4 effects: protection against gastric erosions and depletion of musocal glycoproteins
1990 • 4 citations
Brain Sites Where Bombesin and Corticotropin-Releasing Factor Influence Gastric Secretions
1990 • 4 citations
Age-related changes in the gastric submucosal arterioles and gastric acid secretion
1983 • 4 citations
Species differences in restraint-induced gastric ulcers
1979 • 3 citations
Thrombotic etiology of stress ulcers. 1. The effect of anticoagulant and antiplatelet aggregators in the development of stress ulcers in rats.
1983 • 2 citations
Energy expenditure during stress ulcer formation in vulnerable rats
1989 • 2 citations