Stress and brain noradrenaline: A review

EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS.

1964 • 5,110 citations

Evidence for the existence of monoamine neurons in the central nervous system

1965 • 1,538 citations

Presynaptic regulation of the release of catecholamines.

1980 • 1,483 citations

Central Catecholamine Neuron Systems: Anatomy and Physiology of the Dopamine Systems

1978 • 920 citations

The Metabolism of Fatty Acids in the Rat VI. Arachidonic Acid

1965 • 866 citations

Development of β-adrenergic receptor subsensitivity by antidepressants

1977 • 727 citations

Behavioral depression produced by an uncontrollable stressor: Relationship to norepinephrine, dopamine, and serotonin levels in various regions of rat brain

1981 • 659 citations

Neurobiology of Mood Disorders

1985 • 492 citations

Agonist-induced desensitization of the beta-adrenergic receptor-linked adenylate cyclase.

1983 • 441 citations

Presynaptic modulation of beta adrenergic receptors in rat cerebral cortex after treatment with antidepressants.

1978 • 440 citations

Depression: The predisposing influence of stress

1982 • 431 citations

Effects of stress on the metabolism of norepinephrine, dopamine and serotonin in the central nervous system of the rat. I. Modifications of norepinephrine turnover.

1968 • 403 citations

Catecholamines and Stress

1976 • 390 citations

Receptor-Mediated Endocytosis of Hormones in Cultured Cells

1981 • 388 citations

Metabolism of normetanephrine-H3 in rat brain—identification of conjugated 3-methoxy-4-hydrophenylglycol as the major metabolite

1968 • 368 citations

Morphological and Functional Aspects of Central Monoamine Neurons

1970 • 349 citations

The Psychobiology of the Depressive Disorders: Implications for the Effects of Stress

1980 • 314 citations

β ₁ - and β ₂ -Adrenergic Receptors in Rat Cerebral Cortex Are Independently Regulated

1979 • 296 citations

Metabolism of norepinephrine, serotonin and dopamine in rat brain with stress.

1968 • 291 citations

Alterations in Brain Norepinephrine Metabolism Induced by Environmental Stimuli Previously Paired with Inescapable Shock

1980 • 263 citations

Psychopharmacology: A Generation of Progress

1978 • 252 citations

Catecholamine depletion in mice upon reexposure to stress: Mediation of the escape deficits produced by inescapable shock.

1979 • 238 citations

Prenatal stress: Effects on brain biogenic amine and plasma corticosterone levels

1982 • 236 citations

Brain amines: Response to physiological stress

1963 • 231 citations

Characterization of α1-and α2-Adrenergic Receptors

1983 • 230 citations

3-Methoxy-4-hydroxyphenylglycol sulfate in brain and cerebrospinal fluid

1968 • 229 citations

Regulation of Peptide Hormone Receptors and Gonadal Steroidogenesis

1980 • 228 citations

Escape performance following exposure to inescapable shock: Deficits in motor response maintenance.

1978 • 201 citations

The effect of immobilization stress on the activity of central monoamine neurons

1968 • 199 citations

Effects of differential environments on brain weights and enzyme activities in gerbils, rats, and mice

1969 • 175 citations

Uptake Processes for Biogenic Amines

1975 • 173 citations

Coping Behavior and Neurochemical Changes An Alternative Explanation for the Original "Learned Helplessness" Experiments

1976 • 169 citations

Time-related differences in noradrenaline turnover in rat brain regions by stress

1982 • 167 citations

Problems with current catecholamine hypotheses of antidepressant agents: Speculations leading to a new hypothesis

1983 • 163 citations

Time-dependent variations in aversively motivated behaviors: Nonassociative effects of cholinergic and catecholaminergic activity.

1975 • 143 citations

Psychological stress enhances noradrenaline turnover in specific brain regions in rats

1982 • 142 citations

Part I: Introduction

1980 • 140 citations

Recognition Sites for Norepinephrine Uptake: Regulation by Neurotransmitter

1983 • 129 citations

β-Adrenergic Regulation of α ₃ -Adrenergic Receptors in the Central Nervous System

1980 • 118 citations

Stress-induced depression of motor activity correlates with regional changes in brain norepinephrine but not in dopamine

1980 • 116 citations

Regional characteristics of stress-induced increases in brain noradrenaline release in rats

1983 • 103 citations

Effects of Prenatal Maternal Handling and Differential Housing on Offspring Emotionality, Plasma Corticosterone Levels, and Susceptibility to Gastric Erosions

1968 • 103 citations

Differential effects of morphine on noradrenaline release in brain regions of stressed and non-stressed rats

1983 • 101 citations

CATECHOLAMINES IN INDIVIDUAL HYPOTHALAMIC NUCLEI IN STRESSED RATS11This work was supported in part by The Foundation's Fund for Research in Psychiatry, New Haven, Conn., USA, Research Grant Number G 71 − 498.

1976 • 90 citations

Regional rat brain noradrenaline turnover in response to restraint stress

1983 • 86 citations

Simultaneous determination of noradrenaline and 3-methoxy-4-hydroxyphenylethyleneglycol sulfate in discrete brain regions of the rat

1979 • 86 citations

Restraint ulcer: History, current research and future implications

1980 • 80 citations

Stress during pregnancy: effect on catecholamines in discrete brain regions of offspring as adults

1978 • 79 citations

Naloxene enhances stress-induced increases in noradrenaline turnover in specific brain regions in rats

1982 • 73 citations

MHPG: Basic Mechanisms and Psychopathology

1983 • 68 citations

A study of the sensitivity of rat brain alpha2-adrenoceptors during chronic antidepressant treatments

1982 • 65 citations

Recovery of stress-induced increases in noradrenaline turnover is delayed in specific brain regions of old rats

1984 • 58 citations

Psychological studies of stress ulcer in the rat

1980 • 56 citations

Stress, predisposition and the onset of serious disease: Implications about psychosomatic etiology

1983 • 56 citations

Effects of age and stress on regional noradrenaline metabolism in the rat brain

1982 • 53 citations

Regional Distribution and Production Rate of 3‐Methoxy‐4‐Hydroxyphenylethyleneglycol Sulphate (MHPG‐SO₄) in Rat Brain

1981 • 51 citations

Marked enhancement of noradrenaline turnover in extensive brain regions after activity-stress in rats

1982 • 49 citations

Behavioral and neurochemical effects of acute swim stress are due to hypothermia

1970 • 48 citations

Sites of behavioral and neurochemical action of ACTH-like peptides and neurohypophyseal hormones

1983 • 48 citations

An improved pharmacological procedure for depletion of noradrenaline: pharmacology and assessment of noradrenaline-associated behaviors

1982 • 42 citations

Presynaptic receptors and modulation of neurotransmission: pharmacological implications and therapeutic relevance

1980 • 40 citations

Some characteristics of the ‘functional’ and ‘main storage’ compartments in central catecholaminergic neurons

1973 • 39 citations

Interaction of environmental enrichment and genotype.

1972 • 33 citations

Advances in experimental ulcer

1981 • 30 citations

Daily increase in noradrenaline turnover in brain regions of activity-stressed rats

1983 • 27 citations

Further evidence for the heterogeneous storage of noradrenaline in central noradrenergic terminals

1973 • 26 citations

Rat Brain Norepinephrine Metabolism: Substantial Clearance Through 3,4‐Dihydroxyphenylethyleneglycol Formation

1983 • 23 citations

The Role of Stress in Peptic Ulcer Disease

1979 • 22 citations

Cortical depth changes in enriched and isolated mice

1982 • 17 citations

Animal Models for Human Psychopathology

1976 • 17 citations

Effects of inescapable shock and norepinephrine depletion induced by DSP4 on escape performance

1984 • 16 citations

Limitations of presynaptic theory: no support for feedback control of autonomic effectors.

1984 • 16 citations

3, 4 dihydroxyphenylethyleneglycol (DHPG) formation: The major route of rat brain norepinephrine metabolism

1981 • 14 citations

Presynaptic alpha2- and postsynaptic beta-adrenoceptor sensitivity in slices of rat neocortex after chronic treatment with various antidepressant drugs

1984 • 13 citations

Effects of altered brain noradrenaline level on acute stress pathology in rats.

1983 • 10 citations

Differential modification by opioid agents of acutely enhanced noradrenaline release in discrete brain regions

1983 • 9 citations

Differential effects of clonidine on α1 and α2-adrenoceptors in footshock-induced jumping behavior

1983 • 7 citations

Time course of brain MHPG-SO4 level following stimulation of pre- and post-synapitic .ALPHA.-adrenoceptors by clonidine.

1984 • 2 citations