Alzheimer's β-Amyloid Peptides Compete for Insulin Binding to the Insulin Receptor

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2000 • 745 citations

Brain insulin and insulin receptors in aging and sporadic Alzheimer's disease

1998 • 728 citations

Risk of Dementia among Persons with Diabetes Mellitus: A Population-based Cohort Study

1997 • 683 citations

Association between features of the insulin resistance syndrome and alzheimer's disease independently of apolipoprotein e4 phenotype: cross sectional population based study

1997 • 427 citations

Enhancement of Memory in Alzheimer Disease With Insulin and Somatostatin, but Not Glucose

1999 • 315 citations

Impaired cerebral glucose metabolism and cognitive functioning predict deterioration in mild cognitive impairment

2001 • 292 citations

Insulin regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase‐dependent pathway

2000 • 175 citations

Binding of the dye congo red to the amyloid protein pig insulin reveals a novel homology amongst amyloid-forming peptide sequences

1992 • 174 citations

Insulin-degrading enzyme.

1996 • 167 citations

Cerebral excess release of neurotransmitter amino acids subsequent to reduced cerebral glucose metabolism in early-onset dementia of Alzheimer type

1989 • 148 citations

Increased insulin levels after OGTT load in peripheral blood and cerebrospinal fluid of patients with dementia of Alzheimer type

1991 • 110 citations

Amyloidogenic determinant as a substrate recognition motif of insulin‐degrading enzyme

1998 • 77 citations

Purification and characterization of the human brain insulin receptor.

1986 • 76 citations

The Significance of Glucose Turnover in the Brain in the Pathogenetic Mechanisms of Alzheimer's Disease

1996 • 61 citations

Amyloid beta-protein activates tachykinin receptors and inositol trisphosphate accumulation by synergy with glutamate.

1993 • 55 citations

Alzheimer Disease and Vascular Dementia: Relationships with Fasting Glucose and Insulin Levels

2000 • 45 citations

The insulin‐binding domain of insulin receptor is encoded by exon 2 and exon 3

1992 • 31 citations

Examination of different preparations of human placental plasma membrane for the binding of insulin, transferrin and immunoglobulins

1981 • 27 citations

Energy metabolism inhibition impairs amyloid precursor protein secretion from Alzheimer's fibroblasts

1999 • 27 citations

Expression of 'Alzheimer Antigens' in Cultured Skin Fibroblasts

1991 • 27 citations

Altered phosphofructokinase mRNA levels but unchanged isoenzyme pattern in brains from patients with Alzheimer's disease

2000 • 13 citations

Purification of A14-tyrosyl [125I]iodoinsulinusing C18 reverse-phase cartridges

1992 • 2 citations