Glucose and glucoincretin peptides synergize to induce c‐fos, c‐jun,junB,zif‐268, and nur‐77gene expression in pancreatic β(INS‐1) cells

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

1991 • 3,396 citations

The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases

1995 • 2,441 citations

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines.

1992 • 1,128 citations

Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion

1987 • 773 citations

Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37)

1993 • 576 citations

Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate–early gene nur77

1994 • 551 citations

Cell and Molecular Biology of the Incretin Hormones Glucagon-Like Peptide-I and Glucose-Dependent Insulin Releasing Polypeptide

1995 • 519 citations

Metabolic Fate of Glucose in Purified Islet Cells

1997 • 421 citations

Insulinotropic hormone glucagon-like peptide-I(7-37) stimulation of proinsulin gene expression and proinsulin biosynthesis in insulinoma beta TC-1 cells.

1992 • 323 citations

Glucose stimulates proinsulin biosynthesis by a dose-dependent recruitment of pancreatic beta cells.

1988 • 300 citations

Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet beta-cells.

1994 • 247 citations

Glucose, Other Secretagogues, and Nerve Growth Factor Stimulate Mitogen-activated Protein Kinase in the Insulin-secreting β-Cell Line, INS-1

1995 • 222 citations

Regulation of the Nur77 Orphan Steroid Receptor in Activation-Induced Apoptosis

1995 • 216 citations

New insights into pancreatic β-cell metabolic signaling in insulin secretion

1996 • 197 citations

Regulation of insulin gene expression by glucose and calcium in transfected primary islet cultures.

1990 • 174 citations

Receptors for glucagon-like peptide-1(7–36) amide on rat insulinoma-derived cells

1988 • 153 citations

The biosynthesis of the subtilisin-related proprotein convertase PC3, but no that of the PC2 convertase, is regulated by glucose in parallel to proinsulin biosynthesis in rat pancreatic islets.

1993 • 149 citations

Induction by Glucose of Genes Coding for Glycolytic Enzymes in a Pancreatic β-Cell Line (INS-1)

1997 • 135 citations

Glucose regulates acetyl-CoA carboxylase gene expression in a pancreatic beta-cell line (INS-1).

1993 • 128 citations

The pyruvate kinase gene as a model for studies of glucose-dependent regulation of gene expression in the endocrine pancreatic beta-cell type.

1993 • 126 citations

Role of primary response genes in generating cellular responses to growth factors

1992 • 124 citations

c-Jun represses the human insulin promoter activity that depends on multiple cAMP response elements.

1992 • 109 citations

Differential expression of pituitary adenylate cyclase-activating polypeptide/vasoactive intestinal polypeptide receptor subtypes in clonal pituitary somatotrophs and gonadotrophs.

1995 • 108 citations

junB promoter regulation: Ras mediated transactivation by c-Ets-1 and c-Ets-2.

1994 • 105 citations

Calcium regulation of immediate-early response genes

1994 • 93 citations

Islet cell growth and the growth factors involved

1994 • 80 citations

Transcriptional activation of the inducible nuclear receptor gene nur77 by nerve growth factor and membrane depolarization in PC12 cells.

1993 • 78 citations

Opposing actions of Fos and Jun on transcription of the phosphoenolpyruvate carboxykinase (GTP) gene. Dominant negative regulation by Fos.

1992 • 76 citations

Glucagon-like peptide-1 and control of insulin secretion.

1995 • 74 citations

Measuring the balance between insulin synthesis and insulin release

1991 • 73 citations

Characterization of the murine high Km glucose transporter GLUT2 gene and its transcriptional regulation by glucose in a differentiated insulin-secreting cell line.

1994 • 57 citations

Glucose regulates preproinsulin messenger RNA levels in a clonal cell line of simian virus 40‐transformed B cells

1987 • 54 citations

Specific co-ordinated regulation of PC3 and PC2 gene expression with that of preproinsulin in insulin-producing β TC3 cells

1996 • 50 citations

Diabetes mellitus and impaired pancreatic β‐cell proliferation

1996 • 38 citations

The colonic protein fermentation and insulin resistance hypotheses for colon cancer etiology: experimental tests using precursor lesions

1996 • 26 citations

Glucose-stimulated expressed sequence tags from rat pancreatic islets

1996 • 11 citations

Le proto-oncogène c-fos: un "entremetteur" moléculaire

1992 • 5 citations