Kinetics of T Lymphocyte Development

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.

1984 • 4,180 citations

Monoclonal Antibody to 5-Bromo- and 5-Iododeoxyuridine: A New Reagent for Detection of DNA Replication

1982 • 2,648 citations

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1988 • 1,711 citations

Discrete stages of human intrathymic differentiation: Analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage

1980 • 1,668 citations

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

The Lymphocyte Function Associated LFA-1, CD2, and LFA-3 Molecules: Cell Adhesion Receptors of the Immune System

1987 • 1,104 citations

Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex

1988 • 1,036 citations

Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells.

1988 • 930 citations

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.

1988 • 917 citations

Pulmonary sarcoidosis

2018 • 894 citations

The isolation and characterization of the human suppressor inducer T cell subset.

1985 • 860 citations

The Role of Helper T Cell Products in Mouse B Cell Differentiation and Isotype Regulation

1988 • 764 citations

The isolation and characterization of the human helper inducer T cell subset.

1985 • 708 citations

Leukocyte Typing II

1986 • 688 citations

RHEUMATOID ARTHRITIS: A DISEASE OF T-LYMPHOCYTE/MACROPHAGE IMMUNOREGULATION

1981 • 670 citations

The Role of the T3/Antigen Receptor Complex in T-Cell Activation

1986 • 627 citations

Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells

1985 • 613 citations

Progress in immunology

1968 • 577 citations

T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views.

1980 • 574 citations

Specificity and function of T cells bearing γδ receptors

1988 • 570 citations

Thymus cell migration: Quantitative aspects of cellular traffic from the thymus to the periphery in mice

1980 • 551 citations

Insertion of N regions into heavy-chain genes is correlated with expression of terminal deoxytransferase in B cells

1984 • 540 citations

Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1.

1986 • 515 citations

Distinction of virgin and memory T lymphocytes. Stable acquisition of the Pgp-1 glycoprotein concomitant with antigenic stimulation.

1987 • 505 citations

Gamma interferon is spontaneously released by alveolar macrophages and lung T lymphocytes in patients with pulmonary sarcoidosis.

1985 • 462 citations

The Structure, Function, and Expression of Interleukin-2 Receptors on Normal and Malignant Lymphocytes

1986 • 460 citations

T cell antigen receptors and the immunoglobulin supergene family

1985 • 453 citations

Lymphocyte activation. I. Response of T and B lymphocytes to phytomitogens.

1971 • 413 citations

Simultaneous staining of ribonucleic and deoxyribonucleic acids in unfixed cells using acridine orange in a flow cytofluorometric system.

1977 • 413 citations

T Cell Development in the Adult Murine Thymus: Changes in the Expression of the Surface Antigens Ly2, L3T4 and B2A2 during Development from Early Precursor Cells to Emigrants

1984 • 344 citations

T-cell receptor δ gene rearrangements in early thymocytes

1987 • 324 citations

Genes of the T-Cell Antigen Receptor in Normal and Malignant T Cells

1987 • 321 citations

The adult T-cell receptor 5-chain is diverse and distinct from that of fetal thymocytes

1988 • 320 citations

Early T lymphocytes. Differentiation in vivo of adult intrathymic precursor cells.

1985 • 305 citations

Cross-linking of human T cell receptor proteins: association between the T cell idiotype β subunit and the T3 glycoprotein heavy subunit

1985 • 303 citations

Interspecies spleen-myeloma hybrid producing monoclonal antibodies against mouse lymphocyte surface glycoprotein, T200.

1978 • 282 citations

Distribution of t lymphocyte subsets in the human bone marrow and thymus: an analysis with monoclonal antibodies.

1981 • 275 citations

Heterogeneity of human T4+ inducer T cells defined by a monoclonal antibody that delineates two functional subpopulations.

1982 • 265 citations

Dissection of immunoregulatory subpopulations of T lymphocytes within the helper and suppressor sublineages in man.

1982 • 246 citations

Patterns of gene expression and the cellular origins of human leukaemias

1978 • 242 citations

Characteristics of a monoclonal antibody (WT-31) that recognizes a common epitope on the human T cell receptor for antigen.

1985 • 240 citations

Structural variants of human T200 glycoprotein (leukocyte-common antigen).

1987 • 239 citations

Monoclonal antibody (UCHL1) that recognises normal and neoplastic T cells in routinely fixed tissues.

1986 • 239 citations

Cell surface characterization of malignant T cells from lymphoblastic lymphoma using monoclonal antibodies: evidence for phenotypic differences between malignant T cells from patients with acute lymphoblastic leukemia and lymphoblastic lymphoma

1981 • 226 citations

T cells that help B cell responses to soluble antigen are distinguishable from those producing interleukin 2 on mitogenic or allogeneic stimulation.

1986 • 218 citations

Expression and functional significance of the J11d marker on mouse thymocytes.

1987 • 218 citations

THYMUS CELL MATURATION

1973 • 202 citations

Learning from lesions: patterns of tissue inflammation in leprosy.

1988 • 199 citations

The T3 complex on human T lymphocytes involves four structurally distinct glycoproteins.

1983 • 194 citations

Quantitation of 5-bromo-2-deoxyuridine incorporation into DNA: an enzyme immunoassay for the assessment of the lymphoid cell proliferative response

1985 • 194 citations

Differential expression of two t cell receptors, tcr1 and tcr2, on chicken lymphocytes

1988 • 192 citations

Studies of thymocytopoiesis in rats and mice. I. Kinetics of appearance of thymocytes using a direct intrathymic adoptive transfer assay for thymocyte precursors.

1986 • 188 citations

The Human Thymic Microenvironment: An Immunohistologic Study

1980 • 188 citations

The differentiation of T lymphocytes

1974 • 185 citations

Lymphocyte structure and function

1978 • 184 citations

The cytoplasmic expression of CD3 antigens in normal and malignant cells of the T lymphoid lineage.

1987 • 181 citations

Cell Surface Antigen Expression on Thymocytes: Development and Phenotypic Differentiation of Intrathymic Subsets

1984 • 179 citations

Subpopulations of Thymus Cells and Thymus-Derived Lymphocytes

1971 • 176 citations

Differentiation potential of subsets of CD4−8− thymocytes

1987 • 169 citations

Separate ontogeny of two macrophage-like accessory cell populations in the human fetus.

1986 • 163 citations

Characterization and expression of the human alpha beta T cell receptor by using a framework monoclonal antibody.

1987 • 162 citations

Distinct molecular forms of human T cell receptor gamma/delta detected on viable T cells by a monoclonal antibody.

1988 • 161 citations

Tumor necrosis factor production by human sarcoid alveolar macrophages.

1986 • 157 citations

Hematopoietic thymocyte precursors. I. Assay and kinetics of the appearance of progeny.

1976 • 154 citations

In situ demonstration of T lymphocyte subsets in granulomatous inflammation: leprosy, rhinoscleroma and sarcoidosis.

1983 • 151 citations

Determination of the growth fraction in cell suspensions by flow cytometry using the monoclonal antibody Ki-67

1986 • 150 citations

Immunohistological characterisation of intraepithelial lymphocytes of the human gastrointestinal tract.

1981 • 149 citations

Cytoplasmic expression of the CD3 antigen as a diagnostic marker for immature T-cell malignancies

1988 • 147 citations

The human thymic microenvironment: an immunohistologic study.

1980 • 145 citations

Human lymphocyte differentiation antigens HB-10 and HB-11. II. Differential production of B cell growth and differentiation factors by distinct helper T cell subpopulations.

1985 • 145 citations

Rapid staining methods for analysis of deoxyribonucleic acid and protein in mammalian cells.

1976 • 134 citations

Comparison of T3-associated 49- and 43-kilodalton cell surface molecules on individual human T-cell clones: evidence for peptide variability in T-cell receptor structures.

1983 • 133 citations

The monoclonal antibody, UCHL1, recognizes a 180,000 MW component of the human leucocyte-common antigen, CD45.

1988 • 130 citations

Importance of IL-2 receptors in intra-thymic generation of cells expressing T-cell receptors

1987 • 124 citations

In vivo thymocyte maturation. BUdR labeling of cycling thymocytes and phenotypic analysis of their progeny support the single lineage model.

1986 • 124 citations

The expression of T cell receptor-associated proteins during T cell ontogeny in man.

1989 • 122 citations

Thy‐1 determinants are present on many murine hematopoietic Cells other than T Cells

1982 • 121 citations

Human T cell antigen expression during the early stages of fetal thymic maturation.

1985 • 118 citations

T cell receptor-CD3 complex during early T cell differentiation. Analysis of immature T cell acute lymphoblastic leukemias (T-ALL) at DNA, RNA, and cell membrane level.

1987 • 118 citations

Seeding of thymic microenvironments defined by distinct thymocyte-stromal cell interactions is developmentally controlled.

1987 • 112 citations

The Human Thymus

2013 • 112 citations

Prediction of tumor doubling time in recurrent meningiomas

1986 • 110 citations

Subpopulations of Normal and Leukemic Human Thymocytes: An Analysis With the Use of Monoclonal Antibodies<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1980 • 107 citations

Sequential events in thymocyte differentiation and thymus regeneration revealed by a combination of bromodeoxyuridine DNA labeling and antimitotic drug treatment.

1988 • 107 citations

Expression of antigen-specific, major histocompatibility complex-restricted receptors by cortical and medullary thymocytes in situ

1985 • 106 citations

Purification and characterization of fetal hematopoietic cells that express the common acute lymphoblastic leukemia antigen (CALLA).

1983 • 106 citations

Immunocytochemical detection of interleukin 1 within stimulated human monocytes.

1986 • 105 citations

Functional heterogeneity among the T-derived lymphocytes of the mouse. I. Analysis by adult thymectomy.

1974 • 105 citations

Renewal and fate in the mammalian thymus: Mechanisms and inferences of thymocytokinetics

1972 • 99 citations

The human receptor for T-cell growth factor. Evidence for variable post-translational processing, phosphorylation, sulfation, and the ability of precursor forms of the receptor to bind T-cell growth factor.

1985 • 98 citations

Human T cell subpopulations defined by a monoclonal antibody. I. A small subset is responsible for proliferation to allogeneic cells or to soluble antigens and for helper activity for B cell differentiation.

1982 • 96 citations

Comparative biochemical and tissue distribution study of four distinct CD45 antigen specificities.

1988 • 96 citations

Human bone marrow cells positive for terminal deoxynucleotidyl transferase (TdT), HLA-DR, and a T cell marker may represent prothymocytes.

1985 • 92 citations

Regulation of lymphocyte homing. I. Alterations in homing receptor expression and organ-specific high endothelial venule binding of lymphocytes upon activation.

1988 • 90 citations

Human T cell subsets

1987 • 85 citations

The tissue distribution of T lymphocytes expressing different CD45 polypeptides.

1989 • 83 citations

The role of immunocytochemistry in diagnostic pathology.

1987 • 82 citations

The Lymphocyte Structure and Function.

1977 • 79 citations

A comparison of three methods for the determination of the growth fraction in non-Hodgkin's lymphoma

1987 • 78 citations

CD4+ murine T cells develop from CD8+ precursors in vivo

1987 • 71 citations

Hematopoietic thymocyte precursors

1977 • 69 citations

Double and triple staining methods for studying the proliferative activity of human B and T lymphoid cells

1988 • 67 citations

Cellular Differentiation of Lymphoid Subpopulations and Their Microenvironments in the Human Thymus

1986 • 63 citations

Cellular events during memory T-cell activation in vitro: the UCHL1 (180,000 MW) determinant is newly synthesized after mitosis.

1989 • 57 citations

A single micromanipulated stem cell gives rise to multiple T-cell receptor gene rearrangements in the thymus in vitro

1986 • 57 citations

Functional heterogeneity among the T-derived lymphocytes of the mouse

1975 • 55 citations

Proliferation of normal and malignant human immature lymphoid cells

1988 • 53 citations

The ontogeny of terminal deoxynucleotidyl transferase positive cells in the human fetus

1983 • 51 citations

Immunohistochemical determination of growth fractions in human permanent cell lines and lymphoid tumours: a critical comparison of the monoclonal antibodies OKT9 and Ki‐67

1987 • 50 citations

Myasthenia Gravis: Immunohistological heterogeneity in microenvironmental organization of hyperplastic and neoplastic thymuses suggesting different mechanisms of tolerance breakdown

1986 • 44 citations

A flow cytofluorometric double staining technique for simultaneous determination of human mononuclear cell surface phenotype and cell cycle phase

1987 • 39 citations

Studies on hyperlymphoid mice.

1979 • 35 citations

Microenvironments in haemopoietic and lymphoid differentiation.

1981 • 33 citations

Comparative analysis of [³H]‐thymidine labelling index and monoclonal antibody Ki‐67 in non‐Hodgkin's lymphomas

1988 • 33 citations

Origin of PHA-responsive Cells in the Mouse Thymus after Treatment of the Animal with Hydrocortisone

1971 • 32 citations

Microanatomy of the Thymus: Its Relationship to T Cell Differentiation

1981 • 31 citations

Ontogeny of lymphocyte homing receptor expression in the mouse thymus.

1986 • 25 citations

Identification and cloning of a prethymic precursor T lymphocyte from a population of common acute lymphoblastic leukemia antigen (CALLA)-positive fetal bone marrow cells.

1987 • 23 citations

Limiting dilution analysis of the stem cells for T cell lineage.

1986 • 22 citations

Characterization of prothymocytes with cloning capacity in human bone marrow

1988 • 21 citations

Proliferation of phenotypically immature human thymocytes with and without interleukin 2 receptors.

1986 • 21 citations

Studies of hyperthymic mice. I. The influence of multiple thymus grafts on the size of the peripheral T cell pool and immunological performance.

1978 • 20 citations

Separation of spleen colony-forming units and prothymocytes by use of a monoclonal antibody detecting an H-2K determinant

1984 • 18 citations

Analysis of T cell clones in rheumatoid arthritis

1988 • 17 citations

Relationships between terminal transferase expression, stem cell colonization, and thymic maturation in the avian embryo: studies in thymic chimeras resulting from homospecific and heterospecific grafts.

1985 • 12 citations

The double cascade of lymphoid proliferation: Current challenges and problem areas

1984 • 10 citations

Foreword

1984 • 10 citations

Studies of hyperthymic mice. II. The influence of thymus grafts on cell flow through the peripheral T-cell pool.

1978 • 9 citations

The entry of the prothymocyte into the thymus after lethal irradiation and bone marrow transplantation. II. Time of entry.

1988 • 7 citations

The entry of the prothymocyte into the thymus after lethal irradiation and bone marrow transplantation. I. Seeding of bone marrow cells into the thymus.

1988 • 6 citations

CELL POPULATION CHANGES IN REGENERATING THYMUS GRAFTS

1972 • 5 citations

Evaluation of accessory cell heterogeneity III. role of dendritic cells in the in vitro activation of the antibody response to soluble antigens

1985 • 4 citations

Expression of T Cell Receptor Associated Proteins During Human T Cell Development

1989 • 4 citations

Cells reacting with the monoclonal anti-IL-2 receptor antibody AMT-13 in the regenerating thymus of irradiated mice.

1986 • 1 citations