Identification of a Retinoic Acid Response Element Upstream of the Murine Hox-4.2 Gene

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Homeobox genes and axial patterning

1992 • 2,688 citations

Retinoic Acid Embryopathy

1985 • 1,921 citations

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

1991 • 1,725 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1988 • 1,233 citations

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.

1992 • 1,200 citations

Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid

1991 • 1,007 citations

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

1992 • 966 citations

Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5

1991 • 856 citations

Cloning of murine α and β retinoic acid receptors and a novel receptor γ predominantly expressed in skin

1989 • 804 citations

Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression

1991 • 698 citations

A versatilein vivoandin vitroeukaryotic expression vector for protein engineering

1988 • 686 citations

Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formation

1989 • 612 citations

Retinoic acid receptors and cellular retinoid binding proteins: I. A systematic study of their differential pattern of transcription during mouse organogenesis

1990 • 587 citations

Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox geneHox-#150;1.6

1992 • 537 citations

Retinoic acid receptors and cellular retinoid binding proteins : II. Their differential pattern of transcription during early morphogenesis in mouse embryos

1991 • 527 citations

Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells

1990 • 524 citations

A distinct Hox code for the branchial region of the vertebrate head

1991 • 503 citations

Differential expression of genes encoding α, β and γ retinoic acid receptors and CRABP in the developing limbs of the mouse

1989 • 482 citations

H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes.

1992 • 480 citations

Identification of a DNA sequence responsible for binding of the 1,25-dihydroxyvitamin D3 receptor and 1,25-dihydroxyvitamin D3 enhancement of mouse secreted phosphoprotein 1 (SPP-1 or osteopontin) gene expression.

1990 • 467 citations

MINIREVIEW: Interactions Among a Subfamily of Nuclear Hormone Receptors: The Regulatory Zipper Model

1990 • 428 citations

Retinoids, homeoboxes, and growth factors: Toward molecular models for limb development

1991 • 410 citations

Sequence elements in the human osteocalcin gene confer basal activation and inducible response to hormonal vitamin D3.

1989 • 409 citations

Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene

1992 • 364 citations

Purified hepatocyte nuclear factor 1 interacts with a family of hepatocyte-specific promoters.

1988 • 323 citations

Targeted misexpression of Hox-4.6 in the avian limb bud causes apparent homeotic transformations

1992 • 307 citations

Polarizing activity and retinoid synthesis in the floor plate of the neural tube

1990 • 292 citations

Differential regulation by retinoic acid of the homeobox genes of the four HOX loci in human embryonal carcinoma cells

1991 • 291 citations

Effects of retinoic acid excess on expression of Hox-2.9 and Krox-20 and on morphological segmentation in the hindbrain of mouse embryos.

1991 • 247 citations

Retinoic acid causes abnormal development and segmental patterning of the anterior hindbrain in Xenopus embryos

1991 • 229 citations

Cell adhesion molecules as targets for Hox genes: neural cell adhesion molecule promoter activity is modulated by cotransfection with Hox-2.5 and -2.4.

1992 • 215 citations

Mouse retinoic acid receptor alpha 2 isoform is transcribed from a promoter that contains a retinoic acid response element.

1991 • 212 citations

Multiple cell type-specific proteins differentially regulate target sequence recognition by the α retinoic acid receptor

1990 • 211 citations

Mouse homeo-genes within a subfamily, Hox-1.4, -2.6 and -5.1, display similar anteroposterior domains of expression in the embryo, but show stage- and tissue-dependent differences in their regulation

1989 • 192 citations

Retinoic acid modifies development of the midbrain-hindbrain border and affects cranial ganglion formation in zebrafish embryos

1991 • 188 citations

LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia.

1991 • 171 citations

The late retinoic acid induction of laminin B1 gene transcription involves RAR binding to the responsive element.

1991 • 152 citations

Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2.

1988 • 151 citations

Temporal and regional differences in the expression pattern of distinct retinoic acid receptor-β transcripts in the chick embryo

1991 • 131 citations

HOX4 genes encode transcription factors with potential auto- and cross-regulatory capacities.

1991 • 130 citations

Analysis of the murine Hox-2.7 gene: conserved alternative transcripts with differential distributions in the nervous system and the potential for shared regulatory regions.

1992 • 123 citations

The expression of murine Hox-2 genes id dependent on the differenation pathway and displays a collinear sensitivity to retinoic acid in F9 cels andXenopusembroys

1991 • 119 citations

An autoregulatory element of the murine Hox-4.2 gene.

1992 • 107 citations

Regulation of Gene Expression by Retinoic Acid Receptors

1991 • 103 citations

A human HOX4B regulatory element provides head-specific expression in Drosophila embryos

1992 • 100 citations

The mouse Hox-1.4 gene: primary structure, evidence for promoter activity and expression during development

1989 • 100 citations

The upstream region of the human homeobox gene HOX3D is a target for regulation by retinoic acid and HOX homeoproteins.

1992 • 85 citations

Region-specific enhancers near two mammalian homeo box genes define adjacent rostrocaudal domains in the central nervous system.

1990 • 76 citations

Differential expression of the homeobox gene Hox-1.3 in F9 embryonal carcinoma cells.

1988 • 72 citations

Vitamin D ? Soltriol The heliogenic steroid hormone: Somatotrophic activator and modulator

1988 • 70 citations

Abundant expression of homeobox genes in mouse embryonal carcinoma cells correlates with chemically induced differentiation.

1987 • 66 citations

Molecular mechanisms underlying the expression of the human HOX-5.1 gene

1990 • 47 citations

Independent regulation of HNF-1 alpha and HNF-1 beta by retinoic acid in F9 teratocarcinoma cells.

1991 • 46 citations

Repression of the beta-amyloid gene in a Hox-3.1-producing cell line.

1992 • 31 citations

Post-transcriptional regulation of a murine homeobox gene transcript in F9 embryonal carcinoma cells

1987 • 25 citations

Sequence analysis of the homeobox-containing exon of the murine Hox-4.3 homeogene

1991 • 7 citations