Characterization of a Functional NF-κB Site in the Human Interleukin 1β Promoter: Evidence for a Positive Autoregulatory Loop

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

Interleukin-1 and interleukin-1 antagonism

1991 • 2,276 citations

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.

1989 • 1,660 citations

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

CYTOKINES: COORDINATORS OF IMMUNE AND INFLAMMATORY RESPONSES

1990 • 1,304 citations

Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB"

1990 • 1,202 citations

NF-κB Controls Expression of Inhibitor IκBα: Evidence for an Inducible Autoregulatory Pathway

1993 • 1,141 citations

Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.

1984 • 1,042 citations

Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements

1988 • 984 citations

The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product

1990 • 900 citations

Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal

1990 • 870 citations

Cloning and expression of murine interleukin-1 cDNA in Escherichia coli

1984 • 820 citations

The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B.

1991 • 805 citations

Characterization of an immediate-early gene induced in adherent monocytes that encodes IκB-like activity

1991 • 746 citations

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention.

1992 • 731 citations

Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone.

1989 • 726 citations

DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide

1991 • 604 citations

Activation of HIV gene expression during monocyte differentiation by induction of NF-kB

1989 • 590 citations

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

1989 • 517 citations

Tumor necrosis factor alpha functions in an autocrine manner in the induction of human immunodeficiency virus expression.

1990 • 471 citations

The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control

1990 • 469 citations

Isolation of a rel -related Human cDNAThat Potentially Encodes the 65-kD Subunit of NF-κB

1991 • 448 citations

Purified human IκB can rapidly dissociate the complex of the NF-κB transcription factor with its cognate DNA

1990 • 445 citations

Cloning of an NF-κB subunit which stimulates HIV transcription in synergy with p65

1991 • 410 citations

B cell lymphoma-associated chromosomal translocation involves candidate oncogene lyt-10, homologous to NF-κB p50

1991 • 403 citations

Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor

1989 • 331 citations

Cloning of a mitogen-inducible gene encoding a κB DNA-binding protein with homology to the rel oncogene and to cell-cycle motifs

1990 • 330 citations

The p50 subunit of NF-kappa B associates with the NF-IL6 transcription factor.

1992 • 324 citations

The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression.

1992 • 288 citations

Role of Mononuclear Phagocytes in the Pathogenesis of Human Immunodeficiency Virus Infection

1990 • 277 citations

IκBγ, a 70 kd protein identical to the C-terminal half of p110 NF-κB: A new member of the IκB family

1992 • 274 citations

Human immunodeficiency virus glycoprotein (gp120) induction of monocyte arachidonic acid metabolites and interleukin 1.

1989 • 270 citations

NF-kappa B: a family of inducible and differentially expressed enhancer-binding proteins in human T cells.

1990 • 260 citations

Human tumor necrosis factor alpha gene regulation by virus and lipopolysaccharide.

1990 • 236 citations

The Immunopathogenesis of HIV Infection

1989 • 233 citations

Cloning of the DNA-binding subunit of human nuclear factor kappa B: the level of its mRNA is strongly regulated by phorbol ester or tumor necrosis factor alpha.

1991 • 230 citations

The rel-associated pp40 protein prevents DNA binding of Rel and NF-kappa B: relationship with I kappa B beta and regulation by phosphorylation.

1991 • 210 citations

Genomic sequence for human prointerleukin 1 beta: possible evolution from a reverse transcribed prointerleukin 1 alpha gene

1986 • 205 citations

Two different virus-inducible elements are required for human beta-interferon gene regulation.

1989 • 168 citations

The HIV-1 gp120 envelope protein has the intrinsic capacity to stimulate monokine secretion.

1991 • 168 citations

The 65-kD subunit of NF-kappa B is a receptor for I kappa B and a modulator of DNA-binding specificity.

1990 • 167 citations

I-Rel: a novel rel-related protein that inhibits NF-kappa B transcriptional activity.

1992 • 167 citations

Induction of human interferon gene expression is associated with a nuclear factor that interacts with the NF-kappa B site of the human immunodeficiency virus enhancer

1989 • 135 citations

The c-rel protooncogene product c-Rel but not NF-kappa B binds to the intronic region of the human interferon-gamma gene at a site related to an interferon-stimulable response element.

1992 • 134 citations

Review: Transcriptional and post-transcriptional regulation of interleukin 1 gene expression

1992 • 103 citations

Malignant transformation by mutant Rel proteins

1991 • 96 citations

Differential gene expression of IFN-alpha and tumor necrosis factor-alpha in peripheral blood mononuclear cells from patients with AIDS related complex and AIDS.

1990 • 82 citations

Coordinate enhancement of cytokine gene expression in human immunodeficiency virus type 1-infected promonocytic cells

1990 • 49 citations

Multiple Protein-DNA Interactions within the Human Interferon-β Regulatory Element

1989 • 47 citations

Induction of monocytic differentiation and NF-kappa B-like activities by human immunodeficiency virus 1 infection of myelomonoblastic cells.

1992 • 44 citations

Activation of cytokine genes in HIV-1 infected myelomonoblastic cells by phorbol ester and tumor necrosis factor.

1992 • 31 citations

Modulation of interleukin-1 beta RNA in monocytic cells infected with human immunodeficiency virus-1.

1990 • 30 citations

Cell-specific differences in activation of NF-kappa B regulatory elements of human immunodeficiency virus and beta interferon promoters by tumor necrosis factor

1990 • 27 citations

Inhibition of HIV-1 transmission by interferon and 3′-azido-3′-deoxythymidine during de novo infection of promonocytic cells

1990 • 19 citations

Heterodimerization and transcriptional activation in vitro by NF‐κB proteins

1992 • 12 citations