Multiple mechanisms of interference between transformation and differentiation in thyroid cells.

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

1991 • 1,071 citations

The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain

1991 • 882 citations

Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain

1991 • 626 citations

Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity.

1990 • 545 citations

Functional antagonism between c-Jun and MyoD proteins: A direct physical association

1992 • 424 citations

A thyroid-specific nuclear protein essential for tissue-specific expression of the thyroglobulin promoter.

1989 • 382 citations

Induction of sequence-specific binding of Drosophila heat shock activator protein without protein synthesis

1987 • 382 citations

Pax-8, a paired domain-containing protein, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters.

1992 • 298 citations

Oncogenic conversion by regulatory changes in transcription factors

1991 • 215 citations

Thyroglobulin gene expression is regulated by insulin and insulin-like growth factor I, as well as thyrotropin, in FRTL-5 thyroid cells.

1987 • 194 citations

One- and two-step transformations of rat thyroid epithelial cells by retroviral oncogenes.

1987 • 163 citations

The tissue‐specific expression of the thyroglobulin gene requires interaction between thyroid‐specific and ubiquitous factors

1990 • 94 citations

v-Src and EJ Ras alleviate repression of c-Jun by a cell-specific inhibitor

1991 • 81 citations

Thyroid Peroxidase: Rat cDNA Sequence, Chromosomal Localization in Mouse, and Regulation of Gene Expression by Comparison to Thyroglobulin in Rat FRTL-5 Cells

1989 • 76 citations

Block in the expression of differentiation markers of rat thyroid epithelial cells by transformation with Kirsten murine sarcoma virus.

1982 • 74 citations

Transcription factor phosphorylation: a link between signal transduction and the regulation of gene expression.

1990 • 71 citations

Reversible inhibition of a thyroid-specific trans-acting factor by Ras.

1991 • 68 citations

Dissociation between transformed and differentiated phenotype in rat thyroid epithelial cells after transformation with a temperature-sensitive mutant of the Kirsten murine sarcoma virus.

1983 • 57 citations

Insulin and insulin-like growth factor I regulate a thyroid-specific nuclear protein that binds to the thyroglobulin promoter

1992 • 51 citations

Thyrotropin receptor gene expression in oncogene-transfected rat thyroid cells: Correlation between transformation, loss of thyrotropin-dependent growth, and loss of thyrotropin receptor gene expression

1990 • 42 citations

Cooperation between the polyomavirus middle-T-antigen gene and the human c-myc oncogene in a rat thyroid epithelial differentiated cell line: model of in vitro progression.

1988 • 41 citations

Reactivation of thyroglobulin gene expression in transformed thyroid cells by 5-azacytidine

1989 • 39 citations

Neoplastic transformation inactivates specific trans-acting factor(s) required for the expression of the thyroglobulin gene.

1988 • 35 citations

Chemical modification of charged amino acid moieties alters the electrophoretic mobilities of neurofilament subunits on SDS/polyacrylamide gels

1987 • 35 citations

Human Harvey-ras is biochemically different from Kirsten- or N-ras.

1991 • 30 citations

Retroviral oncogenes: interrelationships between neoplastic transformation and cell differentiation.

1991 • 17 citations

The Deoxyribonucleic Acid Regions Involved in the Hormonal Regulation of Thyroglobulin Gene Expression*

1991 • 14 citations