Simian Virus 40 Early- and Late-Region Promoter Functions Are Enhanced by the 72-Base-Pair Repeat Inserted at Distant Locations and Inverted Orientations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

REGULATORY SEQUENCES INVOLVED IN THE PROMOTION AND TERMINATION OF RNA TRANSCRIPTION

1979 • 2,730 citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

1982 • 1,406 citations

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

High efficiency transformation by direct microinjection of DNA into cultured mammalian cells

1980 • 1,005 citations

E. coli RNA polymerase interacts homologously with two different promoters

1980 • 911 citations

Spliced early mRNAs of simian virus 40

1978 • 817 citations

The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants

1981 • 776 citations

Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: Identification of an upstream control region

1981 • 646 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo.

1980 • 471 citations

DNAase I-hypersensitive sites of chromatin

1981 • 410 citations

Absence of nucleosomes in a fraction of SV40 chromatin between the origin of replication and the region coding for the late leader RNA

1980 • 372 citations

Assembly of newly replicated chromatin

1978 • 360 citations

Construction and analysis of viable deletion mutants of simian virus 40

1976 • 355 citations

DNA sequences necessary for transcription of the rabbit β-globin gene in vivo

1982 • 298 citations

Spacer DNA sequences upstream of the T-A-T-A-A-A-T-A sequence are essential for promotion of H2A histone gene transcription in vivo.

1980 • 287 citations

A stretch of “late” SV40 viral DNA about 400 bp long which includes the origin of replication is specifically exposed in SV40 minichromosomes

1979 • 278 citations

T antigen repression of SV40 early transcription from two promoters

1981 • 247 citations

Sites in simian virus 40 chromatin which are preferentially cleaved by endonucleases

1978 • 230 citations

Defective simian virus 40 genomes: Isolation and growth of individual clones

1974 • 201 citations

Identification of a promoter component involved in positioning the 5' termini of simian virus 40 early mRNAs.

1981 • 162 citations

Simian virus 40 early mRNA's contain multiple 5' termini upstream and downstream from a Hogness-Goldberg sequence; a shift in 5' termini during the lytic cycle is mediated by large T antigen

1981 • 141 citations

Deletions covering the putative promoter region of early mRNAs of simian virus 40 do not abolish T-antigen expression.

1980 • 123 citations

The TATA homology and the mRNA 5′ untranslated sequence are not required for expression of essential adenovirus E1A functions

1982 • 103 citations

Fine structure of the regulatory region of simian virus 40 minichromosomes revealed by DNAase I digestion

1982 • 84 citations

The appearance of DNase I hypersensitive sites at the 5′ end of the late SV40 genes is correlated with the transcriptional switch

1981 • 75 citations

Endonuclease-sensitive regions in SV40 chromatin from cells infected with duplicated mutants

1980 • 39 citations

Simian virus 40-rabbit beta-globin recombinants lacking late mRNA splice sites express cytoplasmic RNAs with altered structures

1982 • 29 citations

Deletion Mutants Which Affect the Nuclease-Sensitive Site in Simian Virus 40 Chromatin

1982 • 16 citations