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Identification of the chimeric protein product of theCBFB-MYH11 fusion gene in inv(16) leukemia cells

Data up to Jan 2025

Published1996
Citations58
References28

Total Citations Per Year

Abstract

References (28)

Fusion Between Transcription Factor CBFβ/PEBP2β and a Myosin Heavy Chain in Acute Myeloid Leukemia

1993 • 760 citations

Association of an Inversion of Chromosome 16 with Abnormal Marrow Eosinophils in Acute Myelomonocytic Leukemia

1983 • 504 citations

AML1, AML2, and AML3, the Human Members of the runt domain Gene-Family: cDNA Structure, Expression, and Chromosomal Localization

1994 • 403 citations

Molecular pathogenesis of the chromosome 16 inversion in the M4Eo subtype of acute myeloid leukemia [see comments]

1995 • 220 citations

Acute myelomonocytic leukemia with abnormal eosinophils and inv(16) or t(16;16) has a favorable prognosis

1986 • 211 citations

PEBP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials.

1994 • 204 citations

Purification of core-binding factor, a protein that binds the conserved core site in murine leukemia virus enhancers.

1992 • 194 citations

Myosin heavy chain isoform diversity in smooth muscle is produced by differential RNA processing

1989 • 187 citations

Detection of fusion transcripts generated by the inversion 16 chromosome in acute myelogenous leukemia

1994 • 168 citations

Two different heavy chains are found in smooth muscle myosin

1986 • 159 citations

Detection of the chromosome 16 CBF beta-MYH11 fusion transcript in myelomonocytic leukemias

1995 • 114 citations

Dual Functions of the AML1/Evi-1 Chimeric Protein in the Mechanism of Leukemogenesis in t(3;21) Leukemias

1995 • 108 citations

Heterogeneity in CBF beta/MYH11 fusion messages encoded by the inv(16)(p13q22) and the t(16;16)(p13;q22) in acute myelogenous leukemia

1995 • 106 citations

Growth inhibition and induction of differentiation of t(8;21) acute myeloid leukemia cells by the DNA-binding domain of PEBP2 and the AML1/MTG8(ETO)-specific antisense oligonucleotide.

1994 • 100 citations

Two smooth muscle myosin heavy chains differ in their light meromyosin fragment

1988 • 85 citations

Role of the COOH-terminal nonhelical tailpiece in the assembly of a vertebrate nonmuscle myosin rod.

1992 • 84 citations

Detection of minimal residual disease in acute myelomonocytic leukemia with abnormal marrow eosinophils by nested polymerase chain reaction with allele specific amplification

1994 • 84 citations

Human smooth muscle myosin heavy chain gene mapped to chromosomal region 16q12

1993 • 76 citations

RT-PCR diagnosis of patients with acute nonlymphocytic leukemia and inv(16)(p13q22) and identification of new alternative splicing in CBFB- MYH11 transcripts

1995 • 67 citations

Nuclear proteins that bind the human gamma-globin gene promoter: alterations in binding produced by point mutations associated with hereditary persistence of fetal hemoglobin.

1988 • 58 citations

Establishment and characterization of a new human leukemia cell line derived from M4E0

1991 • 54 citations

Identification of yeast artificial chromosomes containing the inversion 16 p-arm breakpoint associated with acute myelomonocytic leukemia

1993 • 38 citations

Acute Myeloid Leukemia with Inv(16) Produces a Chimeric Transcription Factor with a Myosin Heavy Chain Tail

1994 • 31 citations

The distribution of heavy-chain isoforms of myosin in airways smooth muscle from adult and neonate humans

1989 • 31 citations

The leukemic core binding factor beta-smooth muscle myosin heavy chain (CBF beta-SMMHC) chimeric protein requires both CBF beta and myosin heavy chain domains for transformation of NIH 3T3 cells.

1995 • 30 citations

Temporal association of marrow eosinophilia with inversion of chromosome 16 in recurrent blast crises of chronic myelogenous leukemia

1992 • 20 citations

Overexpression of Core-Binding Factor α (CBFα) Reverses Cellular Transformation by the CBFβ-Smooth Muscle Myosin Heavy Chain Chimeric Oncoprotein

1995 • 18 citations

Efficiency and limitations of the hn-cDNA library approach for the isolation of human transcribed genes from hybrid cells

1992 • 7 citations

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Identification of the chimeric protein product of theCBFB-MYH11 fusion gene in inv(16)… (1996) – Genes Chromosomes and Cancer | Metascience Observatory Explorer