Caught flat-footed: podocyte damage and the molecular bases of focal glomerulosclerosis

NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

2000 • 1,420 citations

Congenital Nephrotic Syndrome in Mice Lacking CD2-Associated Protein

1999 • 844 citations

Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis

1996 • 708 citations

The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death

2001 • 520 citations

Identification and characterization of podocalyxin--the major sialoprotein of the renal glomerular epithelial cell.

1984 • 506 citations

Immunocytochemical localization of the Heymann nephritis antigen (GP330) in glomerular epithelial cells of normal Lewis rats

1983 • 496 citations

Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin

2001 • 476 citations

The Glomerular Slit Diaphragm Is a Modified Adherens Junction

2000 • 455 citations

Proteinuria and Perinatal Lethality in Mice Lacking NEPH1, a Novel Protein with Homology to NEPHRIN

2001 • 427 citations

Interaction with Podocin Facilitates Nephrin Signaling

2001 • 366 citations

Anuria, Omphalocele, and Perinatal Lethality in Mice Lacking the Cd34-Related Protein Podocalyxin

2001 • 320 citations

AN ELECTRON MICROSCOPE STUDY OF THE GLOMERULUS IN NEPHROSIS, GLOMERULONEPHRITIS, AND LUPUS ERYTHEMATOSUS

1957 • 289 citations

Dystroglycan inside and out

1999 • 282 citations

Unraveling the Mechanisms of Glomerular Ultrafiltration

1999 • 272 citations

Loss of glomerular foot processes is associated with uncoupling of podocalyxin from the actin cytoskeleton

2001 • 254 citations

Structure of Arp2/3 Complex in Its Activated State and in Actin Filament Branch Junctions

2001 • 251 citations

FAT is a component of glomerular slit diaphragms

2001 • 214 citations

Induction of differentiation in cultured rat and human podocytes.

1997 • 212 citations

Nephritogenic mAb 5-1-6 is directed at the extracellular domain of rat nephrin

1999 • 181 citations

Glomerular Expression of Dystroglycans Is Reduced in Minimal Change Nephrosis But Not in Focal Segmental Glomerulosclerosis

2000 • 172 citations

Transgenic mouse model of kidney disease: Insertional inactivation of ubiquitously expressed gene leads to nephrotic syndrome

1990 • 169 citations

Involvement of Lipid Rafts in Nephrin Phosphorylation and Organization of the Glomerular Slit Diaphragm

2001 • 163 citations

Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate

2000 • 154 citations

Basic fibroblast growth factor augments podocyte injury and induces glomerulosclerosis in rats with experimental membranous nephropathy.

1995 • 150 citations

Molecular Cloning and Characterization of Human Podocalyxin-like Protein

1997 • 147 citations

Bidirectional Signaling between Sarcoglycans and the Integrin Adhesion System in Cultured L6 Myocytes

1998 • 142 citations

Transport of molecules across renal glomerular capillaries

1976 • 124 citations

Expression of Agrin, Dystroglycan, and Utrophin in Normal Renal Tissue and in Experimental Glomerulopathies

2000 • 123 citations

Integrin linked kinase as a candidate downstream effector in proteinuria

2001 • 107 citations

Glomerular Overproduction of Oxygen Radicals in Mpv17 Gene-Inactivated Mice Causes Podocyte Foot Process Flattening and Proteinuria

1999 • 100 citations

CD2AP and p130Cas localize to different F-actin structures in podocytes

2001 • 95 citations

Interleukin-4 and Interleukin- 13 Act on Glomerular Visceral Epithelial Cells

2000 • 87 citations

The Membrane-Associated Guanylate Kinase Protein MAGI-1 Binds Megalin and Is Present in Glomerular Podocytes

2001 • 76 citations

Pathogenic antibodies inhibit the binding of apolipoproteins to megalin/gp330 in passive Heymann nephritis.

1997 • 64 citations