Unraveling the Mechanisms of Glomerular Ultrafiltration

Positionally Cloned Gene for a Novel Glomerular Protein—Nephrin—Is Mutated in Congenital Nephrotic Syndrome

1998 • 1,822 citations

Nephrin is specifically located at the slit diaphragm of glomerular podocytes

1999 • 736 citations

Isolation of a heparan sulfate-containing proteoglycan from basement membrane.

1980 • 672 citations

Increased permeability of the glomerular basement membrane to ferritin after removal of glycosaminoglycans (heparan sulfate) by enzyme digestion.

1980 • 650 citations

Type IV collagen: structure, gene organization, and role in human diseases. Molecular basis of Goodpasture and Alport syndromes and diffuse leiomyomatosis.

1993 • 610 citations

Presence of heparan sulfate in the glomerular basement membrane

1979 • 562 citations

POROUS SUBSTRUCTURE OF THE GLOMERULAR SLIT DIAPHRAGM IN THE RAT AND MOUSE

1974 • 555 citations

Anionic sites in the glomerular basement membrane. In vivo and in vitro localization to the laminae rarae by cationic probes.

1979 • 554 citations

Molecular Basis of Proteinuria of Glomerular Origin

1978 • 444 citations

Structure of the Gene for Congenital Nephrotic Syndrome of the Finnish Type (NPHS1) and Characterization of Mutations

1999 • 391 citations

THE MOLECULAR STRUCTURE OF CELL ADHESION MOLECULES

1997 • 344 citations

Structure and function of podocytes: an update

1995 • 329 citations

The tight junction protein ZO-1 is concentrated along slit diaphragms of the glomerular epithelium.

1990 • 325 citations

Basal lamina assembly

1994 • 322 citations

CEA adhesion molecules: multifunctional proteins with signal-regulatory properties

1997 • 284 citations

Massive proteinuria induced in rats by a single intravenous injection of a monoclonal antibody.

1988 • 241 citations

Management of congenital nephrotic syndrome of the Finnish type

1995 • 213 citations

Cell adhesion molecules. 1: immunoglobulin superfamily.

1994 • 210 citations

Congenital nephrotic syndrome of Finnish type. Study of 75 patients.

1976 • 205 citations

Loss of anionic sites from the glomerular basement membrane in aminonucleoside nephrosis.

1978 • 199 citations

Distribution of annionic sites in glomerular basement membranes: their possible role in filtration and attachment.

1976 • 192 citations

Agrin Is a Major Heparan Sulfate Proteoglycan in the Human Glomerular Basement Membrane

1998 • 178 citations

Current status of the structural and functional basis of glomerular filtration and proteinuria.

1991 • 162 citations

Regulation of axonal growth in the vertebrate nervous system by interactions between glycoproteins belonging to two subgroups of the immunoglobulin superfamily.

1992 • 161 citations

Congenital nephrotic syndrome of the Finnish type maps to the long arm of chromosome 19.

1994 • 133 citations

Diversity among tight junctions in rat kidney: glomerular slit diaphragms and endothelial junctions express only one isoform of the tight junction protein ZO-1.

1992 • 113 citations

The First Immunoglobulin-like Neural Cell Adhesion Molecule (NCAM) Domain Is Involved in Double-reciprocal Interaction with the Second Immunoglobulin-like NCAM Domain and in Heparin Binding

1997 • 112 citations

Nephrotic syndrome in newborn and young infants.

1956 • 107 citations

The glomerular capillary wall

1970 • 101 citations

Fine mapping and haplotype analysis of the locus for congenital nephrotic syndrome on chromosome 19q13.1.

1995 • 62 citations

Developmental expression of the nephritogenic antigen of monoclonal antibody 5-1-6.

1995 • 59 citations

Stability and leakiness: Opposing challenges to the glomerulus

1996 • 49 citations

Morphometric study of glomerular slit diaphragms fixed by rapid-freezing and freeze-substitution

1991 • 46 citations

Number of Nephrons in Normal Human Kidneys and Kidneys of Patients with the Congenital Nephrotic Syndrome

1975 • 43 citations

Congenital nephrosis of the Finnish type (CNF): matrix components of the glomerular basement membranes and of cultured mesangial cells

1993 • 32 citations

Structure of the human amyloid-precursor-like protein gene APLP1 at 19q13.1

1998 • 26 citations

Ultrastructural Study of Glomerular Capillary Loops at Different Perf usion Pressures as Revealed by Quick-Freezing, Freeze-Substitution and Conventional Fixation Methods

1997 • 25 citations

Exclusion of eight genes as mutated loci in congenital nephrotic syndrome of the Finnish type

1994 • 22 citations

Composition of the glomerular basement membrane in the congenital nephrotic syndrome of the Finnish type*

1977 • 21 citations

Proteinuria in congenital nephrotic syndrome of the Finnish type.

1980 • 12 citations

[Problems of smallpox vaccination].

1966 • 3 citations