Transient Gene Expression Control: Effects of Transfected DNA Stability and trans-Activation by Viral Early Proteins

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection.

1982 • 1,371 citations

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1983 • 1,358 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

High Efficiency DNA-Mediated Transformation of Primate Cells

1983 • 652 citations

Regulation of Simian Virus 40 Transcription: Sensitive Analysis of the RNA Species Present Early in Infections by Virus or Viral DNA

1979 • 623 citations

Mechanism of activation of early viral transcription by the adenovirus E1A gene product

1981 • 604 citations

Control of herpes simplex virus type 1 mRNA synthesis in cells infected with wild-type virus or the temperature-sensitive mutant tsK

1979 • 496 citations

The adenovirus type 5 E1A transcriptional control region contains a duplicated enhancer element

1983 • 467 citations

Simian virus 40 tandem repeated sequences as an element of the early promoter.

1981 • 462 citations

Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription

1984 • 458 citations

Fine-structure mapping and functional analysis of temperature-sensitive mutants in the gene encoding the herpes simplex virus type 1 immediate early protein VP175

1980 • 436 citations

A herpes simplex virus type 1 function continuously required for early and late virus RNA synthesis

1980 • 429 citations

Characterization of the herpes simplex virion-associated factor responsible for the induction of alpha genes

1983 • 423 citations

Transcriptional activation of cloned human β-globin genes by viral immediate-early gene products

1983 • 373 citations

Activation of the SV40 late promoter: Direct effects of T antigen in the absence of viral DNA replication

1984 • 292 citations

Activation of gene expression by adenovirus and herpesvirus regulatory genes acting in trans and by a cis-acting adenovirus enhancer element

1983 • 250 citations

Mechanisms of DNA uptake by mammalian cells: fate of exogenously added DNA monitored by the use of fluorescent dyes.

1982 • 229 citations

Stimulation of simian virus 40 late gene expression by simian virus 40 tumor antigen.

1984 • 207 citations

Origin-defective Mutants of SV40

1980 • 193 citations

Characterization of the immediate-early functions of pseudorabies virus

1983 • 135 citations

Analysis of DNA sequences which regulate the transcription of a herpes simplex virus immediate early gene

1984 • 113 citations

Structure of the promoter for chicken alpha 2 type I collagen gene.

1981 • 92 citations

Expression of adenovirus E1a and E1b gene products and the Escherichia coli XGPRT gene in KB cells

1983 • 68 citations

Hybrid Selection of Small RNAs by Using Simian Virus 40 DNA: Evidence that the Simian Virus 40-Associated Small RNA Is Synthesized by Specific Cleavage from Large Viral Transcripts

1982 • 16 citations