Suppression of Tumor Formation In Vivo by Expression of the JE Gene in Malignant Cells

Tumor Necrosis Factor (TNF)

1985 • 1,932 citations

A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF

1988 • 1,105 citations

Molecular cloning of gene sequences regulated by platelet-derived growth factor

1983 • 989 citations

Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defense cytokines.

1987 • 983 citations

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity.

1980 • 903 citations

Human IL-3 (multi-CSF): Identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3

1986 • 823 citations

Murine interleukin-4 displays potent anti-tumor activity in vivo

1989 • 790 citations

Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line.

1989 • 753 citations

Human monocyte chemoattractant protein-1 (MCP-1)

1990 • 666 citations

A novel neutrophil-activating factor produced by human mononuclear phagocytes.

1988 • 655 citations

Human monocyte chemoattractant protein‐1 (MCP‐1) Full‐length cDNA cloning, expression in mitogen‐stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE

1989 • 593 citations

A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration

1980 • 589 citations

Purification and partial biochemical characterization of a human monocyte-derived, neutrophil-activating peptide that lacks interleukin 1 activity.

1987 • 542 citations

Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants.

1989 • 497 citations

Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties.

1988 • 444 citations

Macrophage inflammatory proteins 1 and 2: members of a novel superfamily of cytokines

1989 • 435 citations

Tumor necrosis factor: a potent effector molecule for tumor cell killing by activated macrophages.

1986 • 360 citations

Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to beta-thromboglobulin.

1988 • 357 citations

Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF)

1989 • 266 citations

Purification of a monocyte chemotactic factor secreted by nonhuman primate vascular cells in culture

1988 • 263 citations

Properties of monocyte chemotactic and activating factor (MCAF) purified from a human fibrosarcoma cell line.

1990 • 241 citations

Identification of Monocyte Chemotactic Activity Produced by Malignant Cells

1989 • 213 citations

High-frequency transfection of CHO cells using polybrene

1986 • 154 citations

Two inflammatory mediator cytokine genes are closely linked and variably amplified on chromosome 17q

1990 • 119 citations

Translational efficiency of polycistronic mRNAs and their utilization to express heterologous genes in mammalian cells.

1987 • 118 citations

Interferon-inducible gene maps to a chromosomal band associated with a (4;11) translocation in acute leukemia cells.

1987 • 100 citations

Platelet-derived Growth Factor-inducible Gene JE Is a Member of a Family of Small Inducible Genes Related to Platelet Factor 4

1989 • 90 citations

Localization of a human T-cell-specific gene, RANTES (D17S136E), to chromosome 17q11.2-q12

1990 • 75 citations

DEFECTIVE MONOCYTE KILLING IN PATIENTS WITH MALIGNANCIES AND RESTORATION OF FUNCTION DURING CHEMOTHERAPY

1980 • 72 citations

Clustering of cytokine genes on mouse chromosome 11.

1990 • 66 citations

Human platelet factor 4 gene is mapped to 4q12→q21

1987 • 36 citations

Assignment of the human small inducible cytokine A2 gene, SCYA2 (encoding JE or MCP-1), to 17q11.2–12: Evolutionary relatedness of cytokines clustered at the same locus

1991 • 35 citations

Effects of tumor growth on host defenses

1986 • 20 citations

Sigje, a member of the small inducible gene family that includes platelet factor 4 and melanoma growth stimulatory activity, is on mouse Chromosome 11

1989 • 8 citations