Different cis-Acting DNA Elements Control Expression of the Human Apolipoprotein AI Gene in Different Cell Types

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

A system for shotgun DNA sequencing

1981 • 2,710 citations

The plasma lecithin:cholesterol acyltransferase reaction

1968 • 2,415 citations

LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis

1983 • 2,306 citations

Human Hepatocellular Carcinoma Cell Lines Secrete the Major Plasma Proteins and Hepatitis B Surface Antigen

1980 • 2,034 citations

Gene Regulation for Higher Cells: A Theory

1969 • 2,022 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

Rapid similarity searches of nucleic acid and protein data banks.

1983 • 1,577 citations

Estimation of evolutionary distances between homologous nucleotide sequences.

1981 • 1,076 citations

Multiple Point Mutations Affecting the Simian Virus 40 Enhancer

1983 • 883 citations

A protein cofactor of lecithin:Cholesterol acyltransferase

1972 • 722 citations

Cell-Specific Expression of the Rat Insulin Gene: Evidence for Role of Two Distinct 5′ Flanking Elements

1985 • 698 citations

Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes

1983 • 627 citations

Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus.

1982 • 625 citations

Isolation and partial characterization of the Drosophila alcohol dehydrogenase gene.

1980 • 570 citations

Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets.

1985 • 500 citations

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1986 • 420 citations

The human β-interferon gene enhancer is under negative control

1986 • 395 citations

Effect of the human plasma apolipoproteins and phosphatidylcholine acyl donor on the activity of lecithin. Cholesterol acyltransferase

1975 • 392 citations

Apolipoprotein multigene family: tandem organization of human apolipoprotein AI, CIII, and AIV genes.

1985 • 361 citations

Immunoglobulin Heavy-Chain Enhancer Requires One or More Tissue-Specific Factors

1985 • 271 citations

Isolation and characterization of the human apolipoprotein A-I gene.

1983 • 243 citations

Discrete elements within the SV40 enhancer region display different cell-specific enhancer activities.

1987 • 240 citations

Expression of rat apolipoprotein A-IV and A-I genes: mRNA induction during development and in response to glucocorticoids and insulin.

1985 • 231 citations

42 bp element from LDL receptor gene confers end-product repression by sterols when inserted into viral TK promoter

1987 • 220 citations

Structure and evolution of the apolipoprotein multigene family

1986 • 214 citations

The effects of subfractions of high density lipoprotein on cholesterol efflux from cultured fibroblasts. Regulation of low density lipoprotein receptor activity.

1981 • 201 citations

Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes.

1986 • 190 citations

A tissue-specific transcription enhancer from the Drosophila yolk protein 1 gene

1986 • 188 citations

5′ end of hmg CoA reductase gene contains sequences responsible for cholesterol-mediated inhibition of transcription

1985 • 187 citations

SEQ: a nucleotide sequence analysis and recombination system

1982 • 179 citations

Independent control elements that determine yolk protein gene expression in alternative Drosophila tissues.

1985 • 158 citations

The nucleotide and derived amino acid sequence of human apolipoprotein A-IV mRNA and the close linkage of its gene to the genes of apolipoproteins A-I and C-III.

1986 • 156 citations

DNA inversion within the apolipoproteins AI/CIII/AIV-encoding gene cluster of certain patients with premature atherosclerosis.

1987 • 154 citations

Negative control of liver-specific gene expression: cloned human retinol-binding protein gene is repressed in HeLa cells.

1987 • 138 citations

Negative regulation contributes to tissue specificity of the immunoglobulin heavy-chain enhancer.

1987 • 113 citations

Factors that interact with the rat albumin promoter are present both in hepatocytes and other cell types.

1987 • 86 citations

Effects of dietary cholesterol and hypothyroidism on rat apolipoprotein mRNA metabolism.

1987 • 70 citations

Identification of a cDNA clone for mouse apoprotein A-1 (apo A-1) and its use in characterization of apo A-1 mRNA expression in liver and small intestine.

1983 • 53 citations

The chicken ovalbumin promoter is under negative control which is relieved by steroid hormones.

1987 • 52 citations

Vertebrate paleontology

2003 • 37 citations

Intestinal biosynthesis of apolipoproteins in the rat: apoE and apoA-I mRNA translation and regulation

1982 • 25 citations