A critical cytoplasmic domain of the interleukin-5 (IL-5) receptor alpha chain and its function in IL-5-mediated growth signal transduction.

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Human Growth Hormone and Extracellular Domain of Its Receptor: Crystal Structure of the Complex

1992 • 2,236 citations

Cytokine signal transduction

1994 • 1,358 citations

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

1993 • 1,223 citations

Identification of a Ten-Amino Acid Proline-Rich SH3 Binding Site

1993 • 1,205 citations

Structural basis for the binding of proline-rich peptides to SH3 domains

1994 • 1,016 citations

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

1993 • 988 citations

Interleukin-5, eosinophils, and disease

1992 • 771 citations

Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor.

1990 • 650 citations

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.

1993 • 516 citations

Tyrosine Phosphorylation of DNA Binding Proteins by Multiple Cytokines

1993 • 367 citations

A novel dimer configuration revealed by the crystal structure at 2.4 Å resolution of human interleukin-5

1993 • 247 citations

Molecular cloning and expression of the murine interleukin-5 receptor.

1990 • 227 citations

Two distinct functional high affinity receptors for mouse interleukin-3 (IL-3).

1992 • 206 citations

Molecular cloning and expression of the human interleukin 5 receptor.

1992 • 199 citations

Cloning and expression of a gene encoding an interleukin 3 receptor-like protein: identification of another member of the cytokine receptor gene family.

1990 • 192 citations

Identification of the second subunit of the murine interleukin-5 receptor: interleukin-3 receptor-like protein, AIC2B is a component of the high affinity interleukin-5 receptor.

1991 • 144 citations

Multiple Hematopoietic Growth Factors Signal Through Tyrosine Phosphorylation

1990 • 125 citations

Molecular basis of a high affinity murine interleukin-5 receptor.

1991 • 112 citations

Reconstitution of the functional receptors for murine and human interleukin 5.

1993 • 111 citations

Characterization of high-affinity receptors for interleukin 5 on interleukin 5-dependent cell lines.

1989 • 99 citations

Recombinant soluble human interleukin-5 (hIL-5) receptor molecules. Cross-linking and stoichiometry of binding to IL-5.

1993 • 92 citations

Receptors for T cell-replacing factor/interleukin 5. Specificity, quantitation, and its implication.

1988 • 79 citations

Signal transduction mediated by growth hormone receptor and its chimeric molecules with the granulocyte colony-stimulating factor receptor.

1993 • 77 citations

Structure-function analysis of interleukin-5 utilizing mouse/human chimeric molecules.

1991 • 68 citations

Interleukin 5 and interleukin 3 induce serine and tyrosine phosphorylations of several cellular proteins in an interleukin 5-dependent cell line

1990 • 65 citations

Characterization of the murine interleukin 5 receptor by using a monoclonal antibody

1990 • 53 citations

Cytokine Receptors And Signal Transduction

1992 • 45 citations

The GTPase dynamin binds to and is activated by a subset of SH3 domains

1993 • 45 citations

The erythropoietin receptor transmembrane region is necessary for activation by the Friend spleen focus-forming virus gp55 glycoprotein.

1992 • 36 citations

Hematopoietic Growth Factors Activate the Tyrosine Phosphorylation of Distinct Sets of Proteins in Interleukin-3-Dependent Murine Cell Lines

1988 • 35 citations

Cloning of the low-affinity murine granulocyte-macrophage colony stimulating factor receptor and reconstitution of a high-affinity receptor complex

1991 • 12 citations