Cloning of the Human Keratin 18 Gene and Its Expression in Nonepithelial Mouse Cells

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells

1982 • 5,272 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

Preparative and analytical purification of DNA from agarose.

1979 • 1,585 citations

Hybridization of nucleic acids immobilized on solid supports

1984 • 1,357 citations

Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins

1985 • 1,248 citations

A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication

1987 • 1,050 citations

Intermediate Filaments: A Chemically Heterogeneous, Developmentally Regulated Class of Proteins

1982 • 1,021 citations

Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins

1986 • 836 citations

Improvement of the dideoxy chain termination method of DNA sequencing by use of deoxy-7-deazaguanosine triphosphate in place of dGTP

1986 • 717 citations

High efficiency polyoma DNA transfection of chloroquine treated cells

1983 • 711 citations

Differentiation of clonal lines of teratocarcinoma cells: formation of embryoid bodies in vitro.

1975 • 710 citations

Widespread occurrence of intermediate-sized filaments of the vimentin-type in cultured cells from diverse vertebrates

1979 • 642 citations

Alkaline Phosphatase Activity in Mouse Teratoma

1973 • 630 citations

Classification of epidermal keratins according to their immunoreactivity, isoelectric point, and mode of expression.

1984 • 440 citations

Self-assembly of bovine epidermal keratin filaments in vitro

1976 • 388 citations

Adenovirus DNA replication in vitro: identification of a host factor that stimulates synthesis of the preterminal protein-dCMP complex.

1982 • 350 citations

Formation of Cytoskeletal Elements During Mouse Embryogenesis

1980 • 346 citations

Pair formation and promiscuity of cytokeratins: formation in vitro of heterotypic complexes and intermediate-sized filaments by homologous and heterologous recombinations of purified polypeptides.

1985 • 343 citations

Regulation of the cytoskeleton in mesothelial cells: Reversible loss of keratin and increase in vimentin during rapid growth in culture

1983 • 331 citations

Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation.

1980 • 274 citations

Signals for the selection of a splice site in pre-mRNA

1987 • 247 citations

Intermediate Filaments: Conformity and Diversity of Expression and Structure

1985 • 246 citations

Chromosomal position or virus mutation permits retrovirus expression in embryonal carcinoma cells

1986 • 236 citations

Nuclear lamins and cytoplasmic intermediate filament proteins: A growing multigene family

1987 • 235 citations

Construction of coliphage lambda Charon vectors with BamHI cloning sites

1980 • 230 citations

The structure of the vimentin gene

1983 • 227 citations

A comparative study of eight cell lines derived from human testicular teratocarcinoma

1980 • 212 citations

Intermediate filament protein synthesis in preimplantation murine embryos

1983 • 190 citations

Remarkable conservation of structure among intermediate filament genes

1984 • 169 citations

Amino acid sequence and gene organization of cytokeratin no. 19, an exceptional tail-less intermediate filament protein.

1986 • 167 citations

Structure of a gene for the human epidermal 67-kDa keratin.

1985 • 160 citations

Six Distinct Nuclear Factors Interact with the 75-Base-Pair Repeat of the Moloney Murine Leukemia Virus Enhancer

1987 • 146 citations

Complete sequence of a gene encoding a human type I keratin: sequences homologous to enhancer elements in the regulatory region of the gene.

1985 • 142 citations

Site-Specific DNA Binding of Nuclear Factor I: Analyses of Cellular Binding Sites

1985 • 138 citations

Molecular cloning and characterization of the Endo B cytokeratin expressed in preimplantation mouse embryos.

1986 • 136 citations

Differentially expressed bovine cytokeratin genes. Analysis of gene linkage and evolutionary conservation of 5′-upstream sequences.

1987 • 112 citations

Characterization of the hamster desmin gene: Expression and formation of desmin filaments in nonmuscle cells after gene transfer

1985 • 112 citations

Termination-Reinitiation Occurs in the Translation of Mammalian Cell mRNAs

1986 • 109 citations

Identification and immunoprecipitation of cytoskeletal proteins from murine extra-embryonic endodermal cells.

1981 • 107 citations

Developmental expression of murine extra-embryonic endodermal cytoskeletal proteins.

1982 • 103 citations

Creation of a processed pseudogene by retroviral infection

1987 • 100 citations

The transfection of epidermal keratin genes into fibroblasts and simple epithelial cells: Evidence for inducing a type I keratin by a type II gene

1987 • 96 citations

Organization of a type I keratin gene. Evidence for evolution of intermediate filaments from a common ancestral gene.

1985 • 91 citations

Comparison of mouse and human keratin 18: A component of intermediate filaments expressed prior to implantation

1986 • 89 citations

Three Tightly Linked Genes Encoding Human Type I Keratins: Conservation of Sequence in the 5′-Untranslated Leader and 5′-Upstream Regions of Coexpressed Keratin Genes

1986 • 75 citations

Stimulation of the Clonal Growth and Differentiation of Feeder Layer Dependent Mouse Embryonal Carcinoma Cells by β-Mercaptoethanol

1978 • 71 citations

Intermediate Filaments

1986 • 71 citations

One gene and one pseudogene for the cytokeratin endo A.

1985 • 69 citations

Effect of Upstream Reading Frames on Translation Efficiency in Simian Virus 40 Recombinants

1986 • 66 citations

5-Azacytidine is able to induce the conversion of teratocarcinoma-derived mesenchymal cells into epithelia cells.

1984 • 57 citations

Isolation of human DNA sequences that bind to nuclear factor I, a host protein involved in adenovirus DNA replication.

1984 • 51 citations

Clustered arrangement of keratin intermediate filament genes.

1986 • 51 citations

Anomalous Placement of Introns in a Member of the Intermediate Filament Multigene Family: an Evolutionary Conundrum

1986 • 42 citations

Preimplantation mouse embryos and liver express the same type I keratin gene product.

1985 • 32 citations

Molecular Analysis of the First Differentiations in the Mouse Embryo

1985 • 14 citations

S1 Nuclease Protection Assay

1986 • 13 citations