Three Tightly Linked Genes Encoding Human Type I Keratins: Conservation of Sequence in the 5′-Untranslated Leader and 5′-Upstream Regions of Coexpressed Keratin Genes

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells

1982 • 5,272 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 • 1,471 citations

Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

1982 • 1,406 citations

Changes in keratin gene expression during terminal differentiation of the keratinocyte

1980 • 1,059 citations

The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants

1981 • 776 citations

Tropomyosin coiled-coil interactions: Evidence for an unstaggered structure

1975 • 670 citations

Host-specific activation of transcription by tandem repeats from simian virus 40 and Moloney murine sarcoma virus.

1982 • 625 citations

Multiple factors required for accurate initiation of transcription by purified RNA polymerase II.

1980 • 541 citations

A drosophila RNA polymerase II transcription factor binds to the regulatory site of an hsp 70 gene

1984 • 534 citations

The mesothelial keratins: A new family of cytoskeletal proteins identified in cultured mesothelial cells and nonkeratinizing epithelia

1982 • 523 citations

Keratin filaments of cultured human epidermal cells. Formation of intermolecular disulfide bonds during terminal differentiation.

1978 • 501 citations

Formation of stable preinitiation complexes between eukaryotic class B transcription factors and promoter sequences

1983 • 477 citations

The molecular biology of intermediate filaments

1985 • 475 citations

Classification of epidermal keratins according to their immunoreactivity, isoelectric point, and mode of expression.

1984 • 440 citations

The amino acid sequence of chicken muscle desmin provides a common structural model for intermediate filament proteins.

1982 • 432 citations

Shotgun DNA sequencing using cloned DNase I-generated fragments

1981 • 425 citations

Self-assembly of bovine epidermal keratin filaments in vitro

1976 • 388 citations

Specific interaction between enhancer-containing molecules and cellular components

1984 • 374 citations

The 50- and 58-kdalton keratin classes as molecular markers for stratified squamous epithelia: cell culture studies.

1983 • 355 citations

Prediction of beta-turns

1979 • 352 citations

Complete amino acid sequence of a mouse epidermal keratin subunit and implications for the structure of intermediate filaments

1983 • 336 citations

The cDNA sequence of a type II cytoskeletal keratin reveals constant and variable structural domains among keratins

1983 • 326 citations

Two distinct classes of keratin genes and their evolutionary significance

1981 • 309 citations

The cDNA sequence of a human epidermal keratin: Divergence of sequence but conservation of structure among intermediate filament proteins

1982 • 298 citations

The preferential translation of Drosophila hsp70 mRNA requires sequences in the untranslated leader

1985 • 291 citations

Drosophila has one myosin heavy-chain gene with three developmentally regulated transcripts

1983 • 286 citations

The expression of keratin genes in epidermis and cultured epidermal cells

1978 • 264 citations

Proteinchemical characterization of three structurally distinct domains along the protofilament unit of desmin 10 nm filaments

1982 • 242 citations

Influence of single amino acid substitutions on electrophoretic mobility of sodium dodecyl sulfate-protein complexes

1978 • 240 citations

Structure of intermediate filaments

1983 • 195 citations

Keratin gene expression in mouse epidermis and cultured epidermal cells.

1983 • 176 citations

Multiple keratins of cultured human epidermal cells are translated from different mRNA molecules

1979 • 173 citations

Remarkable conservation of structure among intermediate filament genes

1984 • 169 citations

Structure of a gene for the human epidermal 67-kDa keratin.

1985 • 160 citations

A novel mechanism of alternative RNA splicing for the developmentally regulated generation of troponin T isoforms from a single gene

1984 • 157 citations

The polypeptide composition of bovine epidermal α-keratin

1975 • 153 citations

Protein complexes of intermediate-sized filaments: melting of cytokeratin complexes in urea reveals different polypeptide separation characteristics.

1983 • 143 citations

Complete sequence of a gene encoding a human type I keratin: sequences homologous to enhancer elements in the regulatory region of the gene.

1985 • 142 citations

Antiparallel orientation of the two double-stranded coiled-coils in the tetrameric protofilament unit of intermediate filaments

1985 • 131 citations

The sequence of a type II keratin gene expressed in human skin: conservation of structure among all intermediate filament genes.

1985 • 128 citations

Structure of the three-chain unit of the bovine epidermal keratin filament

1978 • 124 citations

Tonofilament differentiation in human epidermis, isolation and polypeptide chain composition of keratinocyte subpopulations

1983 • 122 citations

Tissue specificity of epithelial keratins: differential expression of mRNAs from two multigene families.

1983 • 121 citations

The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins.

1984 • 110 citations

Unraveling the structure of the intermediate filaments

1983 • 99 citations

Identification of two types of keratin polypeptides within the acidic cytokeratin subfamily I

1984 • 95 citations

Alternative Splicing of a Drosophila Tropomyosin Gene Generates Muscle Tropomyosin Isoforms with Different Carboxy-Terminal Ends

1984 • 91 citations

Nucleotide sequence of the lexA gene of Escherichia coli K-12

1981 • 91 citations

Organization of a type I keratin gene. Evidence for evolution of intermediate filaments from a common ancestral gene.

1985 • 91 citations

Epidermal keratin filaments assembled in vitro have masses-per-unit-length that scale according to average subunit mass: structural basis for homologous packing of subunits in intermediate filaments.

1983 • 84 citations

Coiled coil formation and sequence regularities in the helical regions of α-keratin

1978 • 79 citations

Translational products of mRNAs coding for non-epidermal cytokeratins.

1983 • 71 citations

Amino acid sequence diversity between bovine epidermal cytokeratin polypeptides of the basic (type II) subfamily as determined from cDNA clones

1984 • 64 citations

Characterization of bovine keratin genes: similarities of exon patterns in genes coding for different keratins.

1984 • 50 citations

Sequence and expression of a human type II mesothelial keratin.

1985 • 49 citations

The Structure of Intermediate Filaments

1986 • 42 citations

Expression of unusually large keratins during terminal differentiation: balance of type I and type II keratins is not disrupted.

1984 • 40 citations

Tissue Specificity of Epithelial Keratins: Differential Expression of mRNAs from Two Multigene Families

1983 • 40 citations

Prekeratin biosynthesis in human scalp epidermis

1982 • 34 citations