Role of Specific Simian Virus 40 Sequences in the Nuclease-Sensitive Structure in Viral Chromatin

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter

1983 • 1,471 citations

The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants

1981 • 776 citations

Two protein-binding sites in chromatin implicated in the activation of heat-shock genes

1984 • 474 citations

Absence of nucleosomes in a fraction of SV40 chromatin between the origin of replication and the region coding for the late leader RNA

1980 • 372 citations

A stretch of “late” SV40 viral DNA about 400 bp long which includes the origin of replication is specifically exposed in SV40 minichromosomes

1979 • 278 citations

A nucleosome-free region in SV40 minichromosomes

1980 • 254 citations

The repeated GC-rich motifs upstream from the TATA box are important elements of the SV40 early promoter

1983 • 241 citations

Sites in simian virus 40 chromatin which are preferentially cleaved by endonucleases

1978 • 230 citations

Induction of altered chromatin structures by simian virus 40 enhancer and promoter elements

1984 • 217 citations

Territorial limits and functional anatomy of the simian virus 40 replication origin.

1982 • 190 citations

SV40 viral minichromosome: preferential exposure of the origin of replication as probed by restriction endonucleases

1978 • 163 citations

Origin of DNA replication in papovavirus chromatin is recognized by endogenous endonuclease.

1978 • 121 citations

Definition of the simian virus 40 early promoter region and demonstration of a host range bias in the enhancement effect of the simian virus 40 72-base-pair repeat.

1983 • 119 citations

Intracellular forms of simian virus 40 nucleoprotein complexes. I. Methods of isolation and characterization in CV-1 cells

1979 • 97 citations

Mutational dissection of the 21 bp repeat region of the SV40 early promoter reveals that it contains overlapping elements of the early-early and late-early promoters

1984 • 88 citations

Mapping of the late promoter of simian virus 40.

1984 • 75 citations

Simian Virus 40 Early- and Late-Region Promoter Functions Are Enhanced by the 72-Base-Pair Repeat Inserted at Distant Locations and Inverted Orientations

1983 • 55 citations

Construction of a viable SV40 variant containing two functional origins of DNA replication

1978 • 50 citations

Simian Virus 40 Major Late Promoter: an Upstream DNA Sequence Required for Efficient In Vitro Transcription

1984 • 42 citations

Endonuclease-sensitive regions in SV40 chromatin from cells infected with duplicated mutants

1980 • 39 citations

DNA Replication and Chromatin Structure of Simian Virus 40 Insertion Mutants

1984 • 36 citations

Targeted deletions of sequences from closed circular DNA.

1980 • 31 citations

SV40 deletion mutants lacking the 21-bp repeated sequences are viable, but have noncomplementable deficiences

1983 • 26 citations

Deletion Mutants Which Affect the Nuclease-Sensitive Site in Simian Virus 40 Chromatin

1982 • 16 citations

A general approach to construct double deletion mutants of SV40

1979 • 9 citations