A Conserved 28-Base-Pair Element (HF-1) in the Rat Cardiac Myosin Light-Chain-2 Gene Confers Cardiac-Specific and α-Adrenergic-Inducible Expression in Cultured Neonatal Rat Myocardial Cells

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1987 • 3,373 citations

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

1987 • 1,391 citations

Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD

1989 • 1,286 citations

Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD.

1989 • 984 citations

A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts.

1989 • 919 citations

Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload.

1988 • 877 citations

A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program.

1989 • 863 citations

MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer

1989 • 861 citations

The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation

1990 • 794 citations

Identification of MRF4: a new member of the muscle regulatory factor gene family.

1989 • 779 citations

Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy

1990 • 641 citations

Norepinephrine-stimulated hypertrophy of cultured rat myocardial cells is an alpha 1 adrenergic response.

1983 • 618 citations

Myf-6, a new member of the human gene family of myogenic determination factors: evidence for a gene cluster on chromosome 12.

1990 • 508 citations

Herculin, a fourth member of the MyoD family of myogenic regulatory genes.

1990 • 482 citations

[72] Identification of regulatory elements of cloned genes with functional assays

1987 • 477 citations

Alpha- and beta-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells. fos/jun expression is associated with sarcomere assembly; Egr-1 induction is primarily an alpha 1-mediated response.

1990 • 444 citations

Transcripts of α-cardiac and α-skeletal actins are early markers for myogenesis in the mouse embryo

1988 • 330 citations

Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element

1989 • 311 citations

Alpha-skeletal muscle actin mRNA's accumulate in hypertrophied adult rat hearts.

1986 • 282 citations

Cardiac myocyte hypertrophy is associated with c-myc protooncogene expression.

1986 • 263 citations

Myogenic lineage determination and differentiation: Evidence for a regulatory gene pathway

1988 • 253 citations

Localized expression of the atrial natriuretic factor gene during cardiac embryogenesis.

1987 • 234 citations

A muscle-specific enhancer is located at the 3' end of the myosin light-chain 1/3 gene locus.

1988 • 212 citations

Biochemical Mechanisms of Cardiac Hypertrophy

1987 • 192 citations

Alpha 1-adrenergic stimulation of cardiac gene transcription in neonatal rat myocardial cells. Effects on myosin light chain-2 gene expression.

1988 • 185 citations

Effect of cell history on response to helix–loop–helix family of myogenic regulators

1990 • 164 citations

An avian muscle factor related to MyoD1 activates muscle-specific promoters in nonmuscle cells of different germ-layer origin and in BrdU-treated myoblasts.

1989 • 162 citations

Terminally differentiated neonatal rat myocardial cells proliferate and maintain specific differentiated functions following expression of SV40 large T antigen.

1988 • 155 citations

The CArG promoter sequence is necessary for muscle-specific transcription of the cardiac actin gene in Xenopus embryos.

1989 • 140 citations

Structure, organization, and expression of the rat cardiac myosin light chain-2 gene

1989 • 140 citations

Alpha 1-adrenergic receptor stimulation of sarcomeric actin isogene transcription in hypertrophy of cultured rat heart muscle cells.

1989 • 138 citations

Phorbol esters induce immediate-early genes and activate cardiac gene transcription in neonatal rat myocardial cells

1990 • 134 citations

Effects of thyroid hormone on alpha-actin and myosin heavy chain gene expression in cardiac and skeletal muscles of the rat: measurement of mRNA content using synthetic oligonucleotide probes.

1986 • 131 citations

Structure and Expression of the Murine Slow/Cardiac Troponin C Gene

1989 • 111 citations

Analysis of the upstream regions governing expression of the chicken cardiac troponin T gene in embryonic cardiac and skeletal muscle cells.

1988 • 109 citations

Heart myosin light chain 2 gene. Nucleotide sequence of full length cDNA and expression in normal and hypertensive rat.

1986 • 61 citations

Myosin isozyme synthesis and mRNA levels in pressure-overloaded rabbit hearts.

1987 • 60 citations

Identification of a Muscle-specific Enhancer within the 5′-Flanking Region of the Human Myoglobin Gene

1989 • 58 citations

Expression of diverse Na+ channel messenger RNAs in rat myocardium. Evidence for a cardiac-specific Na+ channel.

1989 • 53 citations

Muscle-specific Regulation of a Transfected Rabbit Myosin Heavy Chain βGene Promoter

1989 • 45 citations

Nucleotide sequence of full length cDNAs encoding rat cardiac myosin light chain-2

1988 • 39 citations

Effects of hypoxia on resting potential and transmitter release at cercal afferent, giant interneurone synapses in the cockroach, Periplaneta americana L.

1986 • 7 citations