The E1A 13S Product of Adenovirus 5 Activates Transcription of the Cellular Human HSP70 Gene

Characteristics of a Human Cell Line Transformed by DNA from Human Adenovirus Type 5

1977 • 4,801 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1983 • 1,358 citations

Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70.

1985 • 860 citations

An adenovirus type 5 early gene function regulates expression of other early viral genes.

1979 • 791 citations

Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells

1979 • 785 citations

Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs

1979 • 756 citations

Mechanism of activation of early viral transcription by the adenovirus E1A gene product

1981 • 604 citations

Structure of the adenovirus 2 early mRNAs

1978 • 591 citations

Expression of class I major histocompatibility antigens switched off by highly oncogenic adenovirus 12 in transformed rat cells

1983 • 586 citations

Complex splicing patterns of RNAs from the early regions of adenovirus-2

1979 • 560 citations

Partial transformation of primary rat cells by the leftmost 4.5% fragment of adenovirus 5 DNA

1980 • 463 citations

Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription

1984 • 458 citations

Induction of the synthesis of a 70,000 dalton mammalian heat shock protein by the adenovirus E1A gene product

1982 • 454 citations

Structure of two spliced mRNAs from the transforming region of human subgroup C adenoviruses

1979 • 395 citations

Transcriptional activation of cloned human β-globin genes by viral immediate-early gene products

1983 • 373 citations

Adenovirus E1a proteins repress transcription from the SV40 early promoter

1985 • 366 citations

Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site

1982 • 353 citations

Human HSP70 promoter contains at least two distinct regulatory domains.

1986 • 326 citations

Complete transformation by adenovirus 2 requires both E1A proteins

1984 • 243 citations

Expression of early adenovirus genes requires a viral encoded acidic polypeptide.

1981 • 237 citations

Regulation of the appearance of cytoplasmic RNAs from region 1 of the adenovirus 2 genome

1978 • 184 citations

Adenovirus early region 1A protein activates transcription of a nonviral gene introduced into mammalian cells by infection or transfection.

1984 • 167 citations

Transformation properties of type 5 adenovirus mutants that differentially express the E1A gene products.

1984 • 153 citations

Adenovirus 2 early region 1A stimulates expression of both viral and cellular genes.

1984 • 150 citations

Dissection of overlapping functions within the adenovirus type 5 E1A gene.

1984 • 146 citations

Adenovirus EIIA early promoter: transcriptional control elements and induction by the viral pre-early EIA gene, which appears to be sequence independent.

1985 • 140 citations

An enhancer-like element in the adenovirus E2 promoter contains sequences essential for uninduced and E1A-induced transcription.

1985 • 131 citations

Transformation-defective mutant of adenovirus type 5 containing a single altered E1a mRNA species

1981 • 123 citations

The adenovirus-2 early EIIa transcription unit possesses two overlapping promoters with different sequence requirements for EIa-dependent stimulation.

1985 • 111 citations

Transformation-deficient adenovirus mutant defective in expression of region 1A but not region 1B

1982 • 78 citations

Functions of purified E1A protein microinjected into mammalian cells.

1984 • 71 citations

The adenovirus-2 EIIa eariy gene promoter: sequences required for efficientin vitroandin vivotranscription

1983 • 68 citations

The E1b promoter of Ad12 in mouse L tk- cells is activated by adenovirus region E1a.

1983 • 60 citations

Increased MHC H–2K gene transcription in cultured mouse embryo cells after adenovirus infection

1985 • 56 citations