Induction of the Proto-Oncogene c-jun by Angiotensin II

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Early Signals in the Mitogenic Response

1986 • 1,498 citations

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

1984 • 1,463 citations

Human Proto-Oncogene c- jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

1987 • 1,353 citations

The c-fos protein interacts with c-JunAP-1 to stimulate transcription of AP-1 responsive genes

1988 • 1,352 citations

Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells.

1988 • 1,077 citations

Inhibitors of Angiotensin-Converting Enzyme Prevent Myointimal Proliferation After Vascular Injury

1989 • 1,061 citations

Oncogene jun encodes a sequence-specific trans- activator similar to AP-1

1988 • 940 citations

High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment

1984 • 898 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

The role of the leucine zipper in the fos–jun interaction

1988 • 836 citations

Induction of proto-oncogene JUN/AP-1 by serum and TPA

1988 • 689 citations

Induction of platelet-derived growth factor A-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells.

1989 • 632 citations

Transcriptional activation of c-jun during the G0/G1 transition in mouse fibroblasts

1988 • 578 citations

Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells.

1989 • 558 citations

Fluorescence and bioluminescence measurement of cytoplasmic free calcium

1987 • 522 citations

Fos and Jun bind cooperatively to the AP-1 site: reconstitution in vitro.

1988 • 511 citations

fos-associated cellular p39 is related to nuclear transcription factor AP-1

1988 • 508 citations

Expression of the c- fos Gene and of an fos -Related Gene Is Stimulated by Platelet-Derived Growth Factor

1984 • 445 citations

Angiotensin II Induces c-fos mRNA in Aortic Smooth Muscle

1989 • 401 citations

Functional angiotensin II receptors in cultured vascular smooth muscle cells.

1982 • 346 citations

Alterations in vascular smooth muscle mass in the spontaneously hypertensive rat. Role of cellular hypertrophy, hyperploidy, and hyperplasia.

1982 • 315 citations

Significance of the vascular renin-angiotensin pathway.

1986 • 297 citations

Epidermal growth factor stimulates transcription of the c-jun proto-oncogene in rat fibroblasts

1988 • 289 citations

The leucine repeat motif in Fos protein mediates complex formation with Jun/AP-1 and is required for transformation

1989 • 286 citations

Influence of blood pressure on development of aortic medial smooth muscle hypertrophy in spontaneously hypertensive rats.

1987 • 229 citations

Culture of quiescent arterial smooth muscle cells in a defined serum‐free medium

1983 • 220 citations

Angiotensin II induces c-fos expression in smooth muscle via transcriptional control.

1989 • 206 citations

Vascular smooth muscle cell hypertrophy and hyperploidy in the Goldblatt hypertensive rat.

1983 • 168 citations

Angiotensin II induces expression of the - gene through protein kinase C activation and calcium ion mobilization in cultured vascular smooth muscle cells

1988 • 146 citations

Vascular wall renin in spontaneously hypertensive rats. Potential relevance to hypertension maintenance and antihypertensive effect of captopril.

1982 • 144 citations

The fos Gene as "Master Switch"

1987 • 94 citations

Morphometric evidence for non-pressure-related arterial wall thickening in hypertension.

1988 • 31 citations