Chromosome 7 Suppresses Indefinite Division of Nontumorigenic Immortalized Human Fibroblast Cell Lines KMST-6 and SUSM-1

The limited in vitro lifetime of human diploid cell strains

1965 • 5,595 citations

Tumor Suppressor Genes: The Puzzle and the Promise

1989 • 488 citations

Induction of transformation and continuous cell lines from normal human mammary epithelial cells after exposure to benzo[a]pyrene.

1985 • 416 citations

Genetic analysis of indefinite division in human cells: identification of four complementation groups.

1988 • 358 citations

Evidence for the Recessive Nature of Cellular Immortality

1983 • 286 citations

HUMAN TUMOR SUPPRESSOR GENES

1990 • 266 citations

Quantitation of the frequency of immortalization of normal human diploid fibroblasts by SV40 large T-antigen

1989 • 252 citations

Induction of Cellular Senescence in Immortalized Cells by Human Chromosome 1

1990 • 195 citations

Genetic analysis of indefinite division in human cells: evidence for a cell senescence-related gene(s) on human chromosome 4.

1991 • 179 citations

Progression of human papillomavirus type 18-immortalized human keratinocytes to a malignant phenotype.

1991 • 170 citations

Construction of Mouse A9 Clones Containing a Single Human Chromosome Tagged with Neomycin‐resistance Gene via Microcell Fusion

1989 • 150 citations

Limited lifespan in somatic cell hybrids and cybrids

1980 • 128 citations

Neoplastic transformation of human diploid fibroblasts (KMST‐6) by treatment with ⁶⁰Co gamma rays

1985 • 127 citations

Expression of SV40 T antigen in finite life-span hybrids of normal and SV40-transformed fibroblasts

1981 • 123 citations

Twenty-five loci form a continuous linkage map of markers for human chromosome 7

1989 • 118 citations

Human chromosome 11 contains two different growth suppressor genes for embryonal rhabdomyosarcoma.

1992 • 111 citations

Suppression of tumor growth by senescence in virally transformed human fibroblasts.

1986 • 108 citations

Structural and functional analysis of the human thymidylate synthase gene

1990 • 97 citations

Progress of aging in human diploid cells transformed with a tsA mutant of simian virus 40

1984 • 59 citations

Report of the committee on the genetic constitution of chromosome 11

1989 • 45 citations

Dinucleotide repeat polymorphisms at the D7S435 and D7S440 loci

1990 • 40 citations

Report of the committee on the genetic constitution of chromosome 1

1991 • 21 citations

The human ubiquitin-activating enzyme E1 gene (UBE1) mapped to band Xp11.3→p11.23 by fluorescence in situ hybridization

1992 • 18 citations

Dose-dependent induction of resistance to terminal differentiation in x-irradiated cultures of normal human keratinocytes.

1991 • 11 citations