BRCA1 and BRCA2 Mutation Frequency in Women Evaluated in a Breast Cancer Risk Evaluation Clinic

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1

1994 • 5,994 citations

Identification of the breast cancer susceptibility gene BRCA2

1995 • 3,581 citations

Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21

1990 • 2,505 citations

The Risk of Cancer Associated with Specific Mutations ofBRCA1andBRCA2among Ashkenazi Jews

1997 • 2,255 citations

Localization of a Breast Cancer Susceptibility Gene, BRCA2 , to Chromosome 13q12-13

1994 • 1,884 citations

Risks of cancer in BRCA1-mutation carriers

1994 • 1,865 citations

Prevalence of BRCA1 and BRCA2 Gene Mutations in Patients With Early-Onset Breast Cancer

1999 • 866 citations

Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2

1996 • 762 citations

BRCA1Mutations in Women Attending Clinics That Evaluate the Risk of Breast Cancer

1997 • 693 citations

Conformation-sensitive gel electrophoresis for rapid detection of single-base differences in double-stranded PCR products and DNA fragments: evidence for solvent-induced bends in DNA heteroduplexes.

1993 • 685 citations

Unusual case of Smith‐Lemli‐Opitz syndrome “type II”

1995 • 572 citations

Familial breast-ovarian cancer locus on chromosome 17q12-q23

1991 • 513 citations

Variation in Cancer Risks, by Mutation Position, in BRCA2 Mutation Carriers

2001 • 482 citations

Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk.

1998 • 468 citations

Prevalence and Penetrance of BRCA1 and BRCA2 Gene Mutations in Unselected Ashkenazi Jewish Women With Breast Cancer

1999 • 390 citations

Cancer Risks in Two Large Breast Cancer Families Linked to BRCA2 on Chromosome 13q12‐13

1997 • 389 citations

The carrier frequency of the BRCA2 6174delT mutation among Ashkenazi Jewish individuals is approximately 1%

1996 • 385 citations

Frequency of Breast Cancer Attributable to <EMPH TYPE="ITAL">BRCA1</EMPH> in a Population-Based Series of American Women

1998 • 350 citations

BRCA1 and BRCA2 Mutation Analysis of 208 Ashkenazi Jewish Women with Ovarian Cancer

2000 • 311 citations

Contribution ofBRCA1Mutations to Ovarian Cancer

1997 • 239 citations

Frequency and Carrier Risk Associated with Common BRCA1 and BRCA2 Mutations in Ashkenazi Jewish Breast Cancer Patients

1998 • 223 citations

Screening for Genomic Rearrangements in Families with Breast and Ovarian Cancer Identifies BRCA1 Mutations Previously Missed by Conformation-Sensitive Gel Electrophoresis or Sequencing

2000 • 158 citations

A population study of mutations and LOH at breast cancer gene loci in tumours from sister pairs: two recurrent mutations seem to account for all BRCA1/BRCA2 linked breast cancer in Iceland.

1998 • 50 citations