Cancer Risks in Two Large Breast Cancer Families Linked to BRCA2 on Chromosome 13q12‐13

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1

1994 • 5,994 citations

Identification of the breast cancer susceptibility gene BRCA2

1995 • 3,581 citations

Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21

1990 • 2,505 citations

The Risk of Cancer Associated with Specific Mutations ofBRCA1andBRCA2among Ashkenazi Jews

1997 • 2,255 citations

Localization of a Breast Cancer Susceptibility Gene, BRCA2 , to Chromosome 13q12-13

1994 • 1,884 citations

Risks of cancer in BRCA1-mutation carriers

1994 • 1,865 citations

Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.

1995 • 1,602 citations

Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium.

1993 • 1,269 citations

Genetic analysis of breast cancer in the cancer and steroid hormone study.

1991 • 915 citations

The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds

1996 • 849 citations

Estimates of the gene frequency of BRCA1 and its contribution to breast and ovarian cancer incidence.

1995 • 541 citations

Assignment of a Locus for Familial Melanoma, MLM, to Chromosome 9p13-p22

1992 • 531 citations

A single BRCA2 mutation in male and female breast cancer families from Iceland with varied cancer phenotypes

1996 • 525 citations

Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype–phenotype correlation

1995 • 497 citations

Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene

1997 • 437 citations

Recurrent BRCA2 6174delT mutations in Ashkenazi Jewish women affected by breast cancer

1996 • 306 citations

Risk of prostate, ovarian, and endometrial cancer among relatives of women with breast cancer.

1992 • 188 citations

Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q

1994 • 158 citations

Cancer mortality in relatives of women with breast cancer: The OPCS study

1996 • 117 citations

Segregation analysis incorporating linkage markers. I. Single-locus models with an application to type I diabetes.

1984 • 109 citations

Segregation and linkage analysis of nine Utah breast cancer pedigrees

1988 • 68 citations

Strategies based on marker information for the study of human diseases

1992 • 60 citations

Breast cancer in one family group.

1950 • 28 citations