Comparison of in Vitro and in Vivo Splice Site Selection in κ-Immunoglobulin Precursor mRNA

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression

1987 • 2,333 citations

SPLICING OF MESSENGER RNA PRECURSORS

1986 • 1,233 citations

Trans-complementable copy-number mutants of plasmid ColE1

1980 • 975 citations

High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment

1984 • 898 citations

The rapid generation of oligonucleotide-directed mutations at high frequency using phosphorothioate-modified DNA

1985 • 849 citations

ALTERNATIVE SPLICING: A UBIQUITOUS MECHANISM FOR THE GENERATION OF MULTIPLE PROTEIN ISOFORMS FROM SINGLE GENES

1987 • 712 citations

Speculations on RNA splicing

1981 • 639 citations

A High-Efficiency HeLa Cell Nuclear Transcription Extract

1988 • 612 citations

[15] Detection of specific RNAs or specific fragments of DNA by fractionation in gels and transfer to diazobenzyloxymethyl paper

1979 • 587 citations

U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing

1985 • 568 citations

A role for exon sequences and splice-site proximity in splice-site selection

1986 • 494 citations

Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA

1986 • 389 citations

Alternative splicing caused by RNA secondary structure

1985 • 274 citations

An ordered pathway of snRNP binding during mammalian pre-mRNA splicing complex assembly.

1987 • 272 citations

Signals for the selection of a splice site in pre-mRNA

1987 • 247 citations

The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse kappa immunoglobulin J and C region genes.

1981 • 236 citations

Pre-mRNA splicing in vitro requires intact U4/U6 small nuclear ribonucleoprotein

1986 • 222 citations

RNP particles at splice junction sequences on Drosophila chorion transcripts

1985 • 191 citations

Transcription of mouse kappa chain genes: implications for allelic exclusion.

1980 • 167 citations

The role of nucleotide sequences in splice site selection in eukaryotic pre-messenger RNA

1986 • 148 citations

Neuron-specific alternative RNA processing in transgenic mice expressing a metallothionein-calcitonin fusion gene

1987 • 123 citations

Evidence against a scanning model of RNA splicing.

1983 • 122 citations

Definition of the simian virus 40 early promoter region and demonstration of a host range bias in the enhancement effect of the simian virus 40 72-base-pair repeat.

1983 • 119 citations

Alternatives for splicing: Recognizing the ends of introns

1980 • 113 citations

Functional significance and evolutionary development of the 5′-terminal regions of immunoglobulin variable-region genes

1982 • 105 citations

Splicing pathways of SV40 mRNAs in X. laevis oocytes differ in their requirements for snRNPs

1984 • 98 citations

Ribonucleoprotein Complex Formation During Pre-mRNA Splicing in Vitro

1986 • 93 citations

Splicing of SV40 early pre-mRNA to large T and small t mRNAs utilizes different patterns of lariat branch sites

1987 • 93 citations

Synthetic donor and acceptor splice sites function in an RNA polymerase B (II) transcription unit.

1984 • 51 citations

Factors Influencing Alternative Splice Site Utilization In Vivo

1987 • 48 citations

The Natural 5′ Splice Site of Simian Virus 40 Large T Antigen can be improved by increasing the base Complementarity to U1 RNA

1987 • 29 citations

Accurate 5' splice-site selection in mouse kappa immunoglobulin light chain premessenger RNAs is not cell-type-specific.

1987 • 22 citations

Spontaneous Splicing Mutations at the Dihydrofolate Reductase Locus in Chinese Hamster Ovary Cells

1986 • 16 citations

In Vitro Splicing of Kappa Immunoglobulin Precursor mRNA

1987 • 10 citations

Loss of a Consensus Splice Signal in a Mutant Immunoglobulin Gene Eliminates the CH₁ Domain Exon from the mRNA

1984 • 10 citations