Rhythmic Transcription: The Molecular Basis of Circadian Melatonin Synthesis

Phosphorylation-Dephosphorylation of Enzymes

1979 • 2,205 citations

Cloning and characterization of a mammalian melatonin receptor that mediates reproductive and circadian responses

1994 • 1,099 citations

Handbook of Sensory Physiology

1979 • 957 citations

Indole Metabolism in the Pineal Gland: A Circadian Rhythm in N -Acetyltransferase

1970 • 748 citations

Circadian Rhythms in Cultured Mammalian Retina

1996 • 710 citations

CREM gene: Use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription

1991 • 655 citations

Inducibility and negative autoregulation of CREM: An alternative promoter directs the expression of ICER, an early response repressor

1993 • 592 citations

Spermiogenesis deficiency and germ-cell apoptosis in CREM-mutant mice

1996 • 587 citations

Developmental switch of CREM function during spermatogenesis: from antagonist to activator

1992 • 495 citations

Enzymatic O-Methylation of N-Acetylserotonin to Melatonin

1960 • 427 citations

Activation of protein kinase C potentiates isoprenaline-induced cyclic AMP accumulation in rat pinealocytes

1985 • 415 citations

Adrenergic signals direct rhythmic expression of transcriptional represser CREM in the pineal gland

1993 • 394 citations

Transcription Factors Responsive to cAMP

1995 • 379 citations

Endocrinology and Metabolism.

1988 • 376 citations

Genetic Control of Melatonin Synthesis in the Pineal Gland of the Mouse

1986 • 346 citations

Pineal Serotonin N -Acetyltransferase: Expression Cloning and Molecular Analysis

1995 • 317 citations

Melatonin Content of the Pineal Gland in Different Mouse Strains

1989 • 275 citations

Postsynaptic alpha-adrenergic receptors potentiate the beta-adrenergic stimulation of pineal serotonin N-acetyltransferase.

1983 • 263 citations

Diurnal variation in mRNA encoding serotonin N-acetyltransferase in pineal gland

1995 • 262 citations

Circadian rhythms of melatonin release from individual superfused chicken pineal glands in vitro.

1980 • 257 citations

Atypical Synergisticα₁- andβ-Adrenergic Regulation of Adenosine 3′,5′-Monophosphate and Guanosine 3′,5′- Monophosphate in Rat Pinealocytes

1985 • 256 citations

The functional versatility of CREM is determined by its modular structure.

1993 • 226 citations

Circadian rhythmicity in vertebrate retinas: Regulation by a photoreceptor oscillator

1995 • 225 citations

Temperature-compensated circadian clock in the pineal of Anolis.

1983 • 177 citations

Pineal Melatonin Mediates Photoperiodic Control of Pulsatile Luteinizing Hormone Secretion in the Ewe

1985 • 151 citations

Transcriptional control of circadian hormone synthesis via the CREM feedback loop

1996 • 148 citations

Circadian actions of melatonin at the suprachiasmatic nucleus

1995 • 124 citations

Circadian Expression of Transcription Factor Fra-2 in the Rat Pineal Gland

1995 • 102 citations

Melatonin synthesis: analysis of the more than 150-fold nocturnal increase in serotonin N-acetyltransferase messenger ribonucleic acid in the rat pineal gland

1996 • 98 citations

How Does Melatonin Code for Day Length in the Ewe: Duration of Nocturnal Melatonin Release or Coincidence of Melatonin with a Light-Entrained Sensitive Period?1

1988 • 92 citations

Adaptive inducibility of CREM as transcriptional memory of circadian rhythms

1996 • 88 citations

Chick pineal clock regulates serotonin N -acetyltransferase mRNA rhythm in culture

1997 • 86 citations

Rhythmic transcription and autoregulatory loops: Winding up the biological clock

1994 • 74 citations

Evolution of the Pineal Complex: Correlation of Structure and Function

1984 • 46 citations

Circadian Rhythms: ICER is nicer at night (sir!)

1994 • 35 citations

Developmental maturation of pineal gland function: synchronized CREM inducibility and adrenergic stimulation

1995 • 35 citations

Regulation of β-Adrenergic Function in the Rat Pineal Gland

1978 • 8 citations