CLINICAL PERSPECTIVE: Acromegaly and Cancer: A Problem

Plasma Insulin-Like Growth Factor-I and Prostate Cancer Risk: A Prospective Study

1998 • 2,010 citations

Circulating concentrations of insulin-like growth factor I and risk of breast cancer

1998 • 1,850 citations

A Case–Control Study of Screening Sigmoidoscopy and Mortality from Colorectal Cancer

1992 • 1,757 citations

Risk of Advanced Proximal Neoplasms in Asymptomatic Adults According to the Distal Colorectal Findings

2000 • 1,082 citations

Long-Term Risk of Colorectal Cancer after Excision of Rectosigmoid Adenomas

1992 • 1,078 citations

Criteria for Cure of Acromegaly: A Consensus Statement

2000 • 1,013 citations

Insulin-Like Growth Factor 1 and Prostate Cancer Risk: A Population-Based, Case-Control Study

1998 • 592 citations

EPIDEMIOLOGY OF ACROMEGALY IN THE NEWCASTLE REGION

1980 • 468 citations

Insulin-like growth factor 1 in relation to prostate cancer and benign prostatic hyperplasia

1997 • 376 citations

Colonic neoplasia in asymptomatic persons with negative fecal occult blood tests: influence of age, gender, and family history.

1993 • 348 citations

Plasma insulin-like growth factor-1 (IGF-1) concentrations in human breast cancer

1993 • 276 citations

Mitogenic Signaling of Insulin-like Growth Factor I in MCF-7 Human Breast Cancer Cells Requires Phosphatidylinositol 3-Kinase and Is Independent of Mitogen-activated Protein Kinase

1997 • 262 citations

Mortality and Cancer Incidence in Acromegaly: A Retrospective Cohort Study

1998 • 259 citations

Acromegaly, colonic polyps and carcinoma

1997 • 227 citations

Increased serum deoxycholic acid levels in men with colorectal adenomas

1993 • 226 citations

IGF-I and IGF-II in relation to colorectal cancer

1999 • 190 citations

Growth hormone treatment induces mammary gland hyperplasia in aging primates

1997 • 175 citations

Reduced growth of human breast cancer xenografts in hosts homozygous for the lit mutation.

1996 • 160 citations

Unconjugated secondary bile acids in the serum of patients with colorectal adenomas.

1995 • 140 citations

Insulin and IGF-I Receptors Signaling in Protection from Apoptosis

1999 • 133 citations

Acromegaly and Colon Cancer

1984 • 126 citations

Current Treatment Guidelines for Acromegaly

1998 • 119 citations

Increased epithelial cell proliferation in the colon of patients with acromegaly.

1996 • 119 citations

Growth regulation and co-stimulation of human colorectal cancer cell lines by insulin-like growth factor I, II and transforming growth factor α

1992 • 117 citations

COLON CANCER AND POLYPS IN ACROMEGALY: INCREASED RISK ASSOCIATED WITH FAMILY HISTORY OF COLON CANCER

1990 • 103 citations

Endocrine effects of IGF-I on normal and transformed breast epithelial cells: potential relevance to strategies for breast cancer treatment and prevention

1998 • 101 citations

Ascertainment and natural history of treated acromegaly in Northern Ireland.

1990 • 98 citations

Elevated Growth Hormone Levels in Sera from Breast Cancer Patients

1985 • 96 citations

Colon Polyps in Acromegaly

1991 • 93 citations

Vitamin D analogues suppress IGF-I signalling and promote apoptosis in breast cancer cells

1999 • 84 citations

High frequency of mammary adenocarcinomas in metallothionein promoter-human growth hormone transgenic mice created from two different strains of mice

1992 • 82 citations

Roles of gall bladder emptying and intestinal transit in the pathogenesis of octreotide induced gall bladder stones.

1996 • 76 citations

Gastrointestinal tumors in acromegalic patients.

1985 • 74 citations

Increased incidence of neoplasia in females with acromegaly

1997 • 72 citations

Increased prevalence of colonic adenomas in patients with acromegaly

1994 • 67 citations

Co-stimulation of gastrointestinal tumour cell growth by gastrin, transforming growth factor α and insulin like growth factor-I

1991 • 64 citations

The role of bile composition and physical chemistry in the pathogenesis of octreotide-associated gallbladder stones

1994 • 61 citations

Does acromegaly really predispose to an increased prevalence of gastrointestinal tumours?

1994 • 61 citations

The Prevalence and Characteristics of Colorectal Neoplasia in Acromegaly

2000 • 53 citations

Clinical review 75: Recent advances in pathogenesis, diagnosis, and management of acromegaly

1995 • 53 citations

Use of Colonoscopy to Screen Asymptomatic Adults for Colorectal Cancer

2000 • 43 citations

Hypophysectomy in Treatment of Disseminated Breast Cancer

1962 • 39 citations

The prevalence of colonic polyps in acromegaly: a colonoscopic and pathological study in 103 patients

1995 • 36 citations

Colorectal neoplasia in acromegaly

1999 • 34 citations

Prostatic Hyperplasia: An Unknown Feature of Acromegaly

1998 • 34 citations

Benign and malignant tumors in patients with acromegaly

1991 • 26 citations

High prevalence of colonic polyps in patients with acromegaly. Influence of sex and age

1994 • 22 citations

Acromegaly and Neoplasia

1993 • 19 citations

Tight Control of Growth Hormone: An Attainable Outcome for Acromegaly Treatment

1998 • 17 citations

Insulin-like growth factor I regulates c-myc and GAP-43 messenger ribonucleic acid expression in SH-SY5Y human neuroblastoma cells

1993 • 12 citations

The colonic polyps in the patients with acromegaly

2009 • 11 citations

Increased serum deoxycholic acid levels in acromegalic patients with colorectal neoplasia

1997 • 6 citations