Folic acid supplementation for 3 wk reduces pulse pressure and large artery stiffness independent of MTHFR genotype

Aortic Stiffness Is an Independent Predictor of All-Cause and Cardiovascular Mortality in Hypertensive Patients

2001 • 3,767 citations

A Quantitative Assessment of Plasma Homocysteine as a Risk Factor for Vascular Disease

1995 • 3,645 citations

2003 European Society of Hypertension???European Society of Cardiology guidelines for the management of arterial hypertension*

2003 • 2,946 citations

Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis

2002 • 1,921 citations

Aortic Stiffness Is an Independent Predictor of Primary Coronary Events in Hypertensive Patients

2002 • 1,728 citations

The Effect of Folic Acid Fortification on Plasma Folate and Total Homocysteine Concentrations

1999 • 1,141 citations

Pulse Pressure

1997 • 1,026 citations

Aortic Pulse Wave Velocity Predicts Cardiovascular Mortality in Subjects >70 Years of Age

2001 • 742 citations

Homocysteine and cardiovascular disease: cause or effect?

2000 • 442 citations

Validation of Carotid Artery Tonometry as a Means of Estimating Augmentation Index of Ascending Aortic Pressure

1996 • 402 citations

Estimation of total arterial compliance: an improved method and evaluation of current methods

1986 • 379 citations

Noninvasive determination of aortic input impedance and external left ventricular power output: A validation and repeatability study of a new technique

1992 • 359 citations

Homocyst(e)ine and Risk of Cardiovascular Disease in the Multiple Risk Factor Intervention Trial

1997 • 359 citations

5-Methyltetrahydrofolate, the Active Form of Folic Acid, Restores Endothelial Function in Familial Hypercholesterolemia

1998 • 351 citations

Exercise training increases total systemic arterial compliance in humans

1994 • 325 citations

Effect of homocysteine-lowering treatment with folic acid plus vitamin B6 on progression of subclinical atherosclerosis: a randomised, placebo-controlled trial

2000 • 322 citations

Folic Acid Improves Endothelial Function in Coronary Artery Disease via Mechanisms Largely Independent of Homocysteine Lowering

2002 • 311 citations

Variations in Endothelial Function and Arterial Compliance during the Menstrual Cycle

2001 • 307 citations

Folic acid improves arterial endothelial function in adults with hyperhomocystinemia

1999 • 306 citations

High Homocysteine Levels Are Independently Related to Isolated Systolic Hypertension in Older Adults

1997 • 285 citations

Coronary circulation in dogs with an experimental decrease in aortic compliance

1993 • 280 citations

The Effects of Folic Acid Supplementation on Plasma Total Homocysteine Are Modulated by Multivitamin Use and Methylenetetrahydrofolate Reductase Genotypes

1997 • 277 citations

Arterial compliance increases after moderate-intensity cycling

1997 • 271 citations

Large artery stiffness predicts ischemic threshold in patients with coronary artery disease

2002 • 258 citations

Homocysteine and cardiovascular disease:

2002 • 256 citations

Plasma Homocysteine Predicts Mortality Independently of Traditional Risk Factors and C-Reactive Protein in Patients With Angiographically Defined Coronary Artery Disease

2000 • 238 citations

Effect of folic acid and antioxidant vitamins on endothelial dysfunction in patients with coronary artery disease

2000 • 226 citations

Inhibition of basal nitric oxide synthesis increases aortic augmentation index and pulse wave velocity in vivo

2002 • 216 citations

Dietary Supplementation With Methionine and Homocysteine Promotes Early Atherosclerosis but Not Plaque Rupture in ApoE-Deficient Mice

2001 • 213 citations

Effects of Oral Folic Acid Supplementation on Endothelial Function in Familial Hypercholesterolemia

1999 • 178 citations

Aerobic Exercise Training Does Not Modify Large-Artery Compliance in Isolated Systolic Hypertension

2001 • 174 citations

Effect of the methylenetetrahydrofolate reductase 677C→T mutation on the relations among folate intake and plasma folate and homocysteine concentrations in a general population sample

2003 • 168 citations

Methylenetetrahydrofolate reductase 677C→T genotype modulates homocysteine responses to a folate-rich diet or a low-dose folic acid supplement: a randomized controlled trial,,

2002 • 162 citations

Acetylcysteine Reduces Plasma Homocysteine Concentration and Improves Pulse Pressure and Endothelial Function in Patients With End-Stage Renal Failure

2004 • 146 citations

Folic acid enhances endothelial function and reduces blood pressure in smokers: a randomized controlled trial

2002 • 132 citations

Adverse Influence of Systemic Vascular Stiffening on Cardiac Dysfunction and Adaptation to Acute Coronary Occlusion

1996 • 124 citations

Influence of Homocysteine on Matrix Metalloproteinase-2: Activation and Activity

1999 • 107 citations

Serum Homocysteine in Relation to Mortality and Morbidity From Coronary Heart Disease

2004 • 89 citations

Folate protects against oxidative modification of human LDL

2001 • 86 citations

Hyperhomocysteinemia Evoked by Folate Depletion

2002 • 82 citations

Methylenetetrahydrofolate Reductase Genotypes and Early-Onset Coronary Artery Disease

1999 • 79 citations

Hyperhomocysteinemia induces elastolysis in minipig arteries: Structural consequences, arterial site specificity and effect of captopril-hydrochlorothiazide

1998 • 73 citations

Mild hyperhomocysteinemia is a risk-factor in all etiological subtypes of stroke

2004 • 62 citations

ESTIMATION OF ARTERIAL MECHANICS IN CLINICAL PRACTICE AND AS A RESEARCH TECHNIQUE

1999 • 42 citations

Arterial stiffness is rapidly induced by raising the plasma homocysteine concentration with methionine

2003 • 36 citations

Expression of matrix metalloproteinase‐9 in mononuclear cells of hyperhomocysteinaemic subjects

2003 • 36 citations

Associations between dietary intake of folate and vitamins B-12 and B-6 and self-reported cognitive function and psychological well-being in Australian men and women in midlife.

2004 • 34 citations

Comparative Accuracy of Three Automated Techniques in the Noninvasive Estimation of Central Blood Pressure in Men

1998 • 33 citations

Effect of common methylenetetrahydrofolate reductase gene mutation on coronary artery disease in familial hypercholesterolemia

2000 • 28 citations

Homocysteine modulates the proteolytic potential of human vascular endothelial cells

2004 • 23 citations

Short‐term folic acid supplementation induces variable and paradoxical changes in plasma homocyst(e)ine concentrations

2001 • 18 citations