Identification of a DNA Segment That Is Necessary and Sufficient for α-Specific Gene Control in Saccharomyces cerevisiae: Implications for Regulation of α-Specific and a-Specific Genes

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Experiments in molecular genetics

1972 • 28,260 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Methods in Yeast Genetics

1988 • 4,905 citations

Construction and characterization of new cloning vehicle. II. A multipurpose cloning system

1977 • 3,829 citations

High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules.

1979 • 1,504 citations

Transformation of yeast by a replicating hybrid plasmid

1978 • 1,362 citations

The molecular biology of the yeast saccharomyces: Life cycle and inheritance

1982 • 1,361 citations

In vitro gene fusions that join an enzymatically active beta-galactosidase segment to amino-terminal fragments of exogenous proteins: Escherichia coli plasmid vectors for the detection and cloning of translational initiation signals

1980 • 1,052 citations

Sterile host yeasts (SHY): A eukaryotic system of biological containment for recombinant DNA experiments

1979 • 967 citations

Replacement of chromosome segments with altered DNA sequences constructed in vitro.

1979 • 779 citations

Heme regulates transcription of the CYC1 gene of S. cerevisiae via an upstream activation site

1983 • 667 citations

Structure of a yeast pheromone gene (MFα): A putative α-factor precursor contains four tandem copies of mature α-factor

1982 • 587 citations

Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae.

1981 • 542 citations

Isolation of genes by complementation in yeast: molecular cloning of a cell-cycle gene.

1980 • 502 citations

Distinctly regulated tandem upstream activation sites mediate catabolite repression of the CYC1 gene of S. cerevisiae

1984 • 501 citations

A repressor (MATα2 product) and its operator control expression of a set of cell type specific genes in yeast

1985 • 368 citations

Mutants of Saccharomyces cerevisiae unresponsive to cell division control by polypeptide mating hormone.

1980 • 368 citations

Nucleotide sequences of STE2 and STE3 , cell type-specific sterile genes from Saccharomyces cerevisiae

1985 • 351 citations

Evidence the yeast STE3 gene encodes a receptor for the peptide pheromone a factor: gene sequence and implications for the structure of the presumed receptor.

1986 • 305 citations

Centromeric DNA from Saccharomyces cerevisiae

1982 • 292 citations

Control of cell type in yeast by the mating type locus

1981 • 259 citations

MATα1 protein, a yeast transcription activator, binds synergistically with a second protein to a set of cell-type-specific genes

1987 • 236 citations

Yeast promoters: Positive and negative elements

1984 • 227 citations

Binding of α-factor pheromone to yeast a cells: Chemical and genetic evidence for an α-factor receptor

1983 • 211 citations

A yeast operator overlaps an upstream activation site

1987 • 200 citations

Identification and comparison of two sequence elements that confer cell-type specific transcription in yeast

1985 • 192 citations

Cell Interactions and Regulation of Cell Type in the Yeast Saccharomyces Cerevisiae

1983 • 189 citations

An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast.

1983 • 187 citations

Control of yeast cell type by the mating type locus

1981 • 180 citations

Saccharomyces cerevisiaecontains two discrete genes coding for the α-factor pheromone

1983 • 165 citations

Yeast peptide pheromones, a-factor and α-factor, activate a common response mechanism in their target cells

1986 • 137 citations

Control of yeast cell type by the mating type locus: Positive regulation of the α-specific STE3 gene by the MATα 1 product

1983 • 135 citations

The yeast STE12 product is required for expression of two sets of cell-type-specific genes

1985 • 132 citations

Transcription initiation of the Saccharomyces cerevisiae iso-1-cytochrome c gene

1986 • 121 citations

Induction of the yeast α-specific STE3 gene by the peptide pheromone a-factor

1984 • 97 citations

Protein Transport and Secretion

1986 • 92 citations

Common signal transduction system shared by STE2 and STE3 in haploid cells of Saccharomyces cerevisiae : autocrine cell-cycle arrest results from forced expression of STE2

1987 • 80 citations

Sequences upstream of the STE6 gene required for its expression and regulation by the mating type locus in Saccharomyces cerevisiae.

1986 • 70 citations

Transcriptional control mechanisms

1986 • 50 citations

Extracellular suppression allows mating by pheromone-deficient sterile mutants of Saccharomyces cerevisiae

1983 • 47 citations