Cloning and characterization of ADAM28: evidence for autocatalytic pro-domain removal and for cell surface localization of mature ADAM28

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1989 • 7,496 citations

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.

1990 • 1,423 citations

Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences

1977 • 1,252 citations

Perturbation of vesicular traffic with the carboxylic ionophore monensin

1983 • 890 citations

Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum.

1988 • 871 citations

Astacins, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc‐binding environments (HEXXHXXGXXH and Met‐turn) and topologies and should be grouped into a common family, the ‘metzincins’

1993 • 729 citations

The metzincins — Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc‐peptidases

1995 • 691 citations

A potential fusion peptide and an integrin ligand domain in a protein active in sperm–egg fusion

1992 • 680 citations

Arg-X-Lys/Arg-Arg motif as a signal for precursor cleavage catalyzed by furin within the constitutive secretory pathway

1991 • 590 citations

Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding

1999 • 558 citations

A metalloprotease-disintegrin, MDC9/meltrin-gamma /ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor

1998 • 523 citations

A metalloprotease-disintegrin participating in myoblast fusion

1995 • 492 citations

ADAMs: focus on the protease domain

1998 • 472 citations

Metalloprotease-Disintegrin MDC9: Intracellular Maturation and Catalytic Activity

1999 • 312 citations

A Role for the Disintegrin Domain of Cyritestin, a Sperm Surface Protein Belonging to the ADAM Family, in Mouse Sperm–Egg Plasma Membrane Adhesion and Fusion

1997 • 235 citations

Proteolytic processing of a protein involved in sperm-egg fusion correlates with acquisition of fertilization competence.

1990 • 219 citations

MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.

1996 • 213 citations

The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: structural, functional, and evolutionary implications.

1993 • 182 citations

Metargidin, a Membrane-anchored Metalloprotease-Disintegrin Protein with an RGD Integrin Binding Sequence

1996 • 170 citations

Intracellular Maturation of the Mouse Metalloprotease Disintegrin MDC15

1998 • 167 citations

Molecular cloning of cDNA encoding MS2 antigen, a novel cell surface antigen strongly expressed in murine monocytic lineage

1990 • 124 citations

Evidence for Distinct Serine Protease Activities with a Potential Role in Processing the Sperm Protein Fertilin

1997 • 113 citations

A family of cellular proteins related to snake venom disintegrins.

1994 • 96 citations

MDC-L, a Novel Metalloprotease Disintegrin Cysteine-rich Protein Family Member Expressed by Human Lymphocytes

1999 • 70 citations

Mutation of the Active Site Glutamic Acid of Human Gelatinase A: Effects on Latency, Catalysis, and the Binding of Tissue Inhibitor of Metalloproteinases-1

1994 • 67 citations

Macaque MDC family of proteins: sequence analysis, tissue distribution and processing in the male reproductive tract

1998 • 31 citations

Enhancement of plasma fibrinolysis in vitro by jararhagin, the main haemorrhagic metalloproteinase in Bothrops jararaca venom

1995 • 30 citations

Identification, sequence analysis and expression of transcripts encoding a putative metalloproteinase, eMDC II, in human and macaque epididymis

1999 • 26 citations

Rat MDC family of proteins: Sequence analysis, tissue distribution, and expression in prepubertal and adult rat testis

1997 • 6 citations