Fine Structural Characterization of the Main Immunogenic Region of the Nicotinic Acetylcholine Receptor

Monoclonal antibodies used to probe acetylcholine receptor structure: localization of the main immunogenic region and detection of similarities between subunits.

1980 • 452 citations

Mapping of surface structures of electrophorus acetylcholine receptor using monoclonal antibodies.

1981 • 412 citations

Specificities of antibodies to acetylcholine receptors in sera from myasthenia gravis patients measured by monoclonal antibodies.

1982 • 342 citations

Myasthenia Gravis

1988 • 341 citations

Localization of the main immunogenic region of human muscle acetylcholine receptor to residues 67-76 of the alpha subunit.

1988 • 215 citations

Location of subunits within the acetylcholine receptor by electron image analysis of tubular crystals from Torpedo marmorata.

1987 • 195 citations

Passive transfer of experimental autoimmune myasthenia gravis by monoclonal antibodies to the main immunogenic region of the acetylcholine receptor

1987 • 172 citations

Mapping the Main Immunogenic Region and Toxin-Binding Site of the Nicotinic Acetylcholine Receptor

1987 • 161 citations

Location of antigenic determinants of primary sequences of the subunits of nicotinic acetylcholine receptor by peptide mapping

1986 • 146 citations

Demonstration of a main immunogenic region on acetylcholine receptors from human muscle using monoclonal antibodies to human receptor

1983 • 139 citations

Molecular Structure of the Nicotinic Acetylcholine Receptor

1983 • 138 citations

Role of the main immunogenic region of acetylcholine receptor in myasthenia gravis. An Fab monoclonal antibody protects against antigenic modulation by human sera.

1985 • 106 citations

A Nuclear Magnetic Resonance Investigation of the Aggregation of Acridine Orange in Aqueous Solution

1967 • 70 citations

The acetylcholine receptor molecule: allosteric sites and the ion channel

1987 • 68 citations

Effects of monoclonal antibodies on the function of acetylcholine receptors purified from Torpedo californica and reconstituted into vesicles

1985 • 41 citations

Myasthenia gravis: biology and treatment.

1987 • 32 citations

Localisation of the main immunogenic region of the nicotinic acetylcholine receptor

1986 • 25 citations

Two‐dimensional ¹H‐nmr study of synthetic peptides containing the main immunogenic region of the Torpedo acetylcholine receptor

1989 • 18 citations

Myasthenia gravis studied by monoclonal antibodies to the acetylcholine receptor.

1988 • 16 citations

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