Molecular cloning and characterization of the human dbl proto-oncogene: evidence that its overexpression is sufficient to transform NIH/3T3 cells.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1983 • 1,657 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

1983 • 1,550 citations

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

1984 • 1,463 citations

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

1984 • 1,386 citations

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

1979 • 1,339 citations

The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen

1984 • 1,153 citations

A putative signal peptidase recognition site and sequence in eukaryotic and prokaryotic signal peptides

1983 • 1,143 citations

Amplification of a Novel v- erb B-Related Gene in a Human Mammary Carcinoma

1985 • 1,064 citations

Construction and applications of a highly transmissible murine retrovirus shuttle vector

1984 • 1,020 citations

erb B-2 Is a Potent Oncogene When Overexpressed in NIH/3T3 Cells

1987 • 1,015 citations

A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells.

1983 • 933 citations

Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain.

1977 • 865 citations

Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins

1986 • 836 citations

Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus

1982 • 599 citations

An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family

1987 • 525 citations

The molecular biology of intermediate filaments

1985 • 475 citations

Analysis of two divergent rat genomic clones homologous to the transforming gene of Harvey murine sarcoma virus.

1981 • 302 citations

Antibodies specific for the carboxy- and amino-terminal regions of simian virus 40 large tumor antigen.

1980 • 262 citations

Activation of the Transforming Potential of a Normal Cell Sequence: A Molecular Model for Oncogenesis

1981 • 246 citations

Nuclear lamins and cytoplasmic intermediate filament proteins: A growing multigene family

1987 • 235 citations

The structure of the vimentin gene

1983 • 227 citations

Isolation of a new human oncogene from a diffuse B-cell lymphoma

1985 • 210 citations

Chemical synthesis of a polypeptide predicted from nucleotide sequence allows detection of a new retroviral gene product

1980 • 203 citations

Transcription Control by Oncogenes

1985 • 176 citations

Expression of the normal human sis/PDGF-2 coding sequence induces cellular transformation

1984 • 170 citations

Rat c-raf oncogene activation by a rearrangement that produces a fused protein.

1987 • 80 citations

The predicted DBL oncogene product defines a distinct class of transforming proteins.

1988 • 65 citations

Identification of the protein encoded by the human diffuse B-cell lymphoma (dbl) oncogene.

1986 • 40 citations

Automated preparation of DNA sequences for publication

1986 • 32 citations

Molecular cloning and characterization of an activated human c-raf-1 gene.

1987 • 30 citations

Cysteine-rich regions conserved in amino-terminal halves of raf gene family products and protein kinase C.

1986 • 25 citations

Independently activated dbl oncogenes exhibit similar yet distinct structural alterations.

1987 • 21 citations

Rat c-raf Oncogene Activation by a Rearrangement That Produces a Fused Protein

1987 • 14 citations

Molecular Cloning and Characterization of an Activated Human c-raf-1 Gene

1987 • 13 citations

[Activated c-raf-1 gene from human stomach cancer].

1987 • 5 citations