Cyclic Nucleotide-Activated Channels

A novel multigene family may encode odorant receptors: A molecular basis for odor recognition

1991 • 4,793 citations

Biophysical and Molecular Mechanisms of Shaker Potassium Channel Inactivation

1990 • 1,528 citations

Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment

1985 • 1,213 citations

Cyclic GMP Cascade of Vision

1986 • 1,168 citations

A cyclic nucleotide-gated conductance in olfactory receptor cilia

1987 • 1,134 citations

G _olf : an Olfactory Neuron Specific-G Protein Involved in Odorant Signal Transduction

1989 • 863 citations

Direct activation of cardiac pacemaker channels by intracellular cyclic AMP

1991 • 832 citations

Flow of information in the light-triggered cyclic nucleotide cascade of vision.

1981 • 740 citations

Identification of a Specialized Adenylyl Cyclase That May Mediate Odorant Detection

1990 • 695 citations

Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel

1989 • 663 citations

Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons

1990 • 650 citations

Highly cooperative feedback control of retinal rod guanylate cyclase by calcium ions

1988 • 634 citations

Odorant-sensitive adenylate cyclase may mediate olfactory reception

1985 • 583 citations

Cyclic GMP-Activated Conductance of Retinal Photoreceptor Cells

1989 • 582 citations

Light- and GTP-regulated interaction of GTPase and other proteins with bovine photoreceptor membranes

1980 • 561 citations

A Functional Connection Between the Pores of Distantly Related Ion Channels as Revealed by Mutant K ⁺ Channels

1992 • 479 citations

Isolation and characterization of cGMP phosphodiesterase from bovine rod outer segments.

1979 • 448 citations

Rapid kinetics of second messenger formation in olfactory transduction

1990 • 438 citations

The odorant-sensitive adenylate cyclase of olfactory receptor cells. Differential stimulation by distinct classes of odorants.

1986 • 433 citations

The family of genes encoding odorant receptors in the channel catfish

1993 • 402 citations

Photolyzed rhodopsin catalyzes the exchange of GTP for bound GDP in retinal rod outer segments.

1980 • 391 citations

Extrusion of calcium from rod outer segments is driven by both sodium and potassium gradients

1989 • 374 citations

Light dependent phosphorylation of rhodopsin by ATP

1972 • 370 citations

A new subunit of the cyclic nucleotide-gated cation channel in retinal rods

1993 • 370 citations

Light‐induced binding of 48‐kDa protein to photoreceptor membranes is highly enhanced by phosphorylation of rhodopsin

1984 • 358 citations

Coding of olfactory information: Topography of odorant receptor expression in the catfish olfactory epithelium

1993 • 353 citations

Light-activated phosphodiesterase of the rod outer segment. Kinetics and parameters of activation and deactivation.

1978 • 353 citations

Electrogenic Na–Ca exchange in retinal rod outer segment

1984 • 346 citations

Cyclic GMP-sensitive conductance of retinal rods consists of aqueous pores

1986 • 336 citations

Single cyclic GMP-activated channel activity in excised patches of rod outer segment membrane

1986 • 335 citations

Structure of the Adrenergic and Related Receptors

1989 • 300 citations

Rapid activation of alternative second messenger pathways in olfactory cilia from rats by different odorants.

1990 • 292 citations

Odor Stimuli Trigger Influx of Calcium Into Olfactory Neurons of the Channel Catfish

1990 • 287 citations

Photoisomerization, energy storage, and charge separation: A model for light energy transduction in visual pigments and bacteriorhodopsin

1979 • 270 citations

The ionic selectivity and calcium dependence of the light‐sensitive pathway in toad rods.

1985 • 269 citations

Molecular cloning and single-channel properties of the cyclic nucleotide-gated channel from catfish olfactory neurons

1992 • 264 citations

1990: Annus Mirabilis of Potassium Channels

1991 • 261 citations

Primary structure of cAMP‐gated channel from bovine olfactory epithelium

1990 • 260 citations

Cyclic GMP and calcium: The internal messengers of excitation and adaptation in vertebrate photoreceptors

1990 • 258 citations

Receptor cell responses to odorants: Similarities and differences among odorants

1984 • 250 citations

cGMP phosphodiesterase of retinal rods is regulated by two inhibitory subunits.

1988 • 246 citations

Identification, purification, and functional reconstitution of the cyclic GMP-dependent channel from rod photoreceptors.

1987 • 239 citations

The concentration of cytosolic free calcium in vertebrate rod outer segments measured with fura-2

1988 • 234 citations

The cyclic nucleotide-gated channels of vertebrate photoreceptors and olfactory epithelium

1991 • 224 citations

Light response of vertebrate photoreceptors

1990 • 208 citations

Cation selectivity of light-sensitive conductance in retinal rods

1984 • 205 citations

A 26 kd calcium binding protein from bovine rod outer segments as modulator of photoreceptor guanylate cyclase.

1991 • 198 citations

Properties of cyclic nucleotide-gated channels mediating olfactory transduction. Activation, selectivity, and blockage.

1992 • 193 citations

Ca2+-dependent adaptive properties in the solitary olfactory receptor cell of the newt

1990 • 187 citations

Activation of the sensory current in salamander olfactory receptor neurons depends on a G protein-mediated cAMP second messenger system

1991 • 185 citations

Calcium and magnesium fluxes across the plasma membrane of the toad rod outer segment.

1988 • 179 citations

Control of ligand specificity in cyclic nucleotide-gated channels from rod photoreceptors and olfactory epithelium.

1991 • 179 citations

Gating kinetics of the cyclic-GMP-activated channel of retinal rods: flash photolysis and voltage-jump studies.

1988 • 169 citations

Activation by odorants of cation‐selective conductance in the olfactory receptor cell isolated from the newt.

1989 • 165 citations

Calcium modulation of cyclic GMP synthesis in rat visual cells

1982 • 153 citations

Human rod photoreceptor cGMP-gated channel: amino acid sequence, gene structure, and functional expression

1992 • 150 citations

The spatial distributions of odorant sensitivity and odorant‐induced currents in salamander olfactory receptor cells.

1991 • 150 citations

A cyclic GMP-activated channel in dissociated cells of the chick pineal gland

1991 • 149 citations

Patch‐clamp recordings of the light‐sensitive dark noise in retinal rods from the lizard and frog.

1985 • 147 citations

The response induced by intracellular cyclic AMP in isolated olfactory receptor cells of the newt.

1990 • 141 citations

Measurement of sodium‐calcium exchange in salamander rods.

1987 • 140 citations

Time course of the membrane current underlying sensory transduction in salamander olfactory receptor neurones.

1990 • 138 citations

Similarities in Amino Acid Sequences of Drosophila eag and Cyclic Nucleotide-Gated Channels

1991 • 133 citations

Odorants of the same odor class activate different second messenger pathways

1991 • 131 citations

The cGMP-gated channel of the rod photoreceptor cell characterization and orientation of the amino terminus.

1991 • 129 citations

Predicted structures of the cGMP binding domains of the cGMP-dependent protein kinase: a key alanine/threonine difference in evolutionary divergence of cAMP and cGMP binding sites

1989 • 124 citations

Chapter 5 First Stage of Amplification in the Cyclic-Nucleotide Cascade of Vision

1981 • 121 citations

Inhibition of the olfactory cyclic nucleotide gated ion channel by intracellular calcium

1991 • 121 citations

Effect of ions on retinal rods from Bufo marinus.

1984 • 108 citations

Ion transport by the Na-Ca exchange in isolated rod outer segments.

1988 • 104 citations

Olfactory GTP-binding protein: signal-transducing polypeptide of vertebrate chemosensory neurons.

1986 • 102 citations

Analysis of single cyclic nucleotide-gated channels in olfactory receptor cells

1991 • 100 citations

Current recording from sensory cilia of olfactory receptor cells in situ. I. The neuronal response to cyclic nucleotides.

1991 • 99 citations

Cation interactions within the cyclic GMP‐activated channel of retinal rods from the tiger salamander.

1992 • 97 citations

Light-induced decreases in cGMP concentration precede changes in membrane permeability in frog rod photoreceptors.

1984 • 96 citations

Subsecond deactivation of transducin by endogenous GTP hydrolysis

1990 • 95 citations

Blockage and permeation of divalent cations through the cyclic GMP‐activated channel from tiger salamander retinal rods.

1991 • 91 citations

ODOR DISCRIMINATION BY FROG OLFACTORY RECEPTORS

1974 • 90 citations

Monovalent selectivity of the cyclic guanosine monophosphate-activated ion channel.

1990 • 89 citations

Olfactory transduction: cross-talk between second-messenger systems

1990 • 83 citations

Cytosolic protein concentration is the primary volume signal for swelling-induced [K-Cl] cotransport in dog red cells.

1992 • 82 citations

Olfactory adenylate cyclase of the rat Stimulation by odorants and inhibition by Ca2+

1986 • 78 citations

Guanylate cyclase in rod outer segments of the toad retina

1986 • 77 citations

Currents carried by monovalent cations through cyclic GMP‐activated channels in excised patches from salamander rods.

1990 • 77 citations

Transduction proteins of olfactory receptor cells: identification of guanine nucleotide binding proteins and protein kinase C

1987 • 75 citations

High density cAMP-gated channels at the ciliary membrane in the olfactory receptor cell

1991 • 74 citations

Photoreceptor channel activation by nucleotide derivatives

1989 • 74 citations

Light-activated GTPase in vertebrate photoreceptors

1977 • 74 citations

Ionic movements through light‐sensitive channels of toad rods.

1983 • 68 citations

Primary events in olfactory reception

1987 • 62 citations

Cyclic nucleotide‐activated channels in the frog olfactory receptor plasma membrane

1990 • 61 citations

Gigaseal patch clamp recordings from outer segments of intact retinal rods

1982 • 58 citations

Kinetics of light-sensitive channels in vertebrate photoreceptors

1985 • 57 citations

The permeability of the cGMP‐activated channel to organic cations in retinal rods of the tiger salamander.

1993 • 56 citations

Lectin Binding and Enzymatic Deglycosylation of the cGMP-Gated Channel from Bovine Rod Photoreceptors

1989 • 55 citations

Rapid declines in cyclic GMP of rod outer segments of intact frog photoreceptors after illumination.

1986 • 42 citations

Chemical Senses: Receptor Events and Transduction in Taste and Olfaction

1989 • 38 citations

Single unit recording from olfactory cilia

1990 • 37 citations

Cyclic GMP‐activated channels of salamander retinal rods: spatial distribution and variation of responsiveness.

1992 • 36 citations

The ionic selectivity of the light‐sensitive current in isolated rods of the tiger salamander.

1988 • 36 citations

The modulation of the ionic selectivity of the light‐sensitive current in isolated rods of the tiger salamander.

1988 • 34 citations

Cyclic AMP‐Dependent Protein Phosphorylation in Chemosensory Neurons: Identification of Cyclic Nucleotide‐Regulated Phosphoproteins in Olfactory Cilia

1986 • 28 citations

Regional distribution of cGMP-activated ion channels in the plasma membrane of the rod photoreceptor

1988 • 24 citations

Molecular Mechanics of the Cyclic-GMP-activated Channel of Retinal Rods

1988 • 22 citations

Single cyclic nucleotide-activated ion channel activity in olfactory receptor cell soma membrane

1990 • 11 citations

Cation Selectivity of the cGMP-Gated Channel of Mammalian Rod Photoreceptors

1990 • 8 citations

A quantitative model of phototransduction and light adaptation in amphibian rod photoreceptors

1992 • 6 citations