The role of stem cell factor (c-kit ligand) and inflammatory cytokines in pulmonary mast cell activation

Predominant T_H2-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma

1992 • 2,802 citations

The kit Ligand, Stem Cell Factor

1993 • 653 citations

Interleukin 4 is localized to and released by human mast cells.

1992 • 589 citations

T cells and eosinophils in the pathogenesis of asthma

1992 • 585 citations

Interleukin 10: a novel stimulatory factor for mast cells and their progenitors.

1991 • 514 citations

Induction of differentiation of human mast cells from bone marrow and peripheral blood mononuclear cells by recombinant human stem cell factor/kit-ligand in long-term culture

1992 • 436 citations

B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells

1987 • 355 citations

Cytokine production by mast cells and basophils

1991 • 344 citations

The c-kit receptor ligand functions as a mast cell chemoattractant

1992 • 281 citations

Human Th1 and Th2 lymphocytes: their role in the pathophysiology of atopy

1992 • 280 citations

The c-kit ligand, stem cell factor, promotes mast cell survival by suppressing apoptosis.

1994 • 279 citations

Recombinant human stem cell factor stimulates differentiation of mast cells from dispersed human fetal liver cells

1992 • 238 citations

Stem cell factor induces mast cell adhesion to fibronectin.

1994 • 205 citations

Steel factor and c-kit regulate cell-matrix adhesion

1994 • 178 citations

The effect of recombinant mast cell growth factor on purified murine hematopoietic stem cells.

1991 • 157 citations

The rat c-kit ligand, stem cell factor, induces c-kit receptor-dependent mouse mast cell activation in vivo. Evidence that signaling through the c-kit receptor can induce expression of cellular function.

1992 • 145 citations

Activation of MAP kinases, pp90^rsk and pp70‐S6 kinases in mouse mast cells by signaling through the c‐kit receptor tyrosine kinase or FcϵRI: rapamycin inhibits activation of pp70‐S6 kinase and proliferation in mouse mast cells

1993 • 90 citations

Production of Interleukin-4 and Other Cytokines following Stimulation of Mast Cell Lines and in vivo Mast Cells/Basophils

1991 • 88 citations

T Lymphocytes and Their Products in Atopic Allergy and Asthma

1991 • 82 citations

IL-3-dependent mast cells attach to plate-bound vitronectin. Demonstration of augmented proliferation in response to signals transduced via cell surface vitronectin receptors.

1992 • 72 citations

Role of T-lymphocytes and lymphokines

1992 • 55 citations

Early Changes in T Lymphocytes Recovered by Bronchoalveolar Lavage after Local Allergen Challenge of Asthmatic Airways

1992 • 53 citations

Stem cell factor has histamine releasing activity in rat connective tissue-type mast cells

1992 • 49 citations

Increased Numbers of Th2-Like CD4+ T Cells in Target Organs and in the Allergen-Specific Repertoire of Allergic Patients

1991 • 41 citations

Effects of interleukins on connective tissue type mast cells co-cultured with fibroblasts.

1991 • 37 citations

Mast cell-mediated inflammation in asthma.

1989 • 36 citations

T cells and asthma. II. Regulation of the eosinophilia of asthma by T cell cytokines.

1991 • 28 citations

Changing processes from bone marrow-derived cultured mast cells to connective tissue-type mast cells in the peritoneal cavity of mast cell-deficient w/wv mice: association of proliferation arrest and differentiation.

1987 • 27 citations

Proliferation and Functional Responses of Bone Marrow-Derived Mast Cells after Activation

1993 • 16 citations

Characterization of a T-cell-derived mast cell costimulatory activity (MCA) that acts synergistically with interleukin 3 and interleukin 4 on the growth of murine mast cells

1990 • 9 citations