Structure and expression of the gene encoding CD8α chain (Leu-2/T8)

The “initiator” as a transcription control element

1989 • 1,597 citations

The relationship of CD16 (Leu-11) and Leu-19 (NKH-1) antigen expression on human peripheral blood NK cells and cytotoxic T lymphocytes.

1986 • 1,106 citations

T Cell Subsets and the Recognition of MHC Class

1983 • 702 citations

Cell-cell adhesion mediated by CD8 and MHC class I molecules

1988 • 445 citations

The isolation and sequence of the gene encoding T8: A molecule defining functional classes of T lymphocytes

1985 • 325 citations

A second subunit of CD8 is expressed in human T cells.

1988 • 155 citations

Lyt-2 and lyt-3 antigens are on two different polypeptide subunits linked by disulfide bonds. Relationship of subunits to T cell cytolytic activity.

1981 • 142 citations

Two Lyt-2 polypeptides arise from a single gene by alternative splicing patterns of mRNA

1985 • 135 citations

Spontaneous release of the Leu-2 (T8) molecule from human T cells.

1983 • 120 citations

Isolation of the gene encoding the human T-lymphocyte differentiation antigen Leu-2 (T8) by gene transfer and cDNA subtraction.

1984 • 108 citations

Direct evidence for binding of CD8 to HLA class I antigens.

1989 • 103 citations

Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions.

1985 • 101 citations

The T cell differentiation antigen Leu-2/T8 is homologous to immunoglobulin and T cell receptor variable regions

1985 • 79 citations

A conserved sequence in the T-cell receptor beta-chain promoter region.

1988 • 74 citations

The human Lyt-3 molecule requires CD8 for cell surface expression.

1988 • 65 citations

A second chain of human CD8 is expressed on peripheral blood lymphocytes.

1988 • 64 citations

Striking similarities between antigen receptor J pieces and sequence in the second chain of the murine CD8 antigen

1986 • 57 citations

Immunochemical analysis of the released Leu-2 (T8) molecule.

1984 • 54 citations

Alternatively spliced mRNA encodes a secreted form of human CD8 alpha. Characterization of the human CD8 alpha gene.

1989 • 52 citations

A secreted form of the human lymphocyte cell surface molecule CD8 arises from alternative splicing.

1989 • 52 citations

Structure, sequence, and polymorphism of the Lyt-2 T cell differentiation antigen gene.

1986 • 51 citations

Formal proof that different-size Lyt-2 polypeptides arise from differential splicing and post-transcriptional regulation.

1986 • 41 citations

Molecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to immunoglobulin and T-cell receptor variable and joining regions.

1987 • 36 citations

A human homolog of the mouse CD8 molecule, Lyt-3: genomic sequence and expression

1987 • 32 citations

Molecular characterization of the murine cytotoxic T-cell membrane glycoprotein Ly-3 (CD8).

1987 • 24 citations

Isolation and characterization of the gene for the murine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2

1987 • 22 citations

Isolation and characterization of the mouse CD8 beta-chain (Ly-3) genes. Absence of an intervening sequence between V- and J-like gene segments.

1989 • 17 citations

An improved method to make sequential deletion mutants for DNA sequencing.

1989 • 15 citations