Immune dysfunction in cancer patients.

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights

1996 • 5,936 citations

NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses

1998 • 5,178 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

The Biology of Vascular Endothelial Growth Factor

1997 • 4,359 citations

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

1996 • 3,664 citations

Vascular endothelial growth factor (VEGF) and its receptors

1999 • 3,498 citations

NF-κB: Ten Years After

1996 • 3,008 citations

Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells

1996 • 1,908 citations

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

1995 • 1,739 citations

Molecular and Biological Properties of the Vascular Endothelial Growth Factor Family of Proteins

1992 • 1,612 citations

NF-κB: A lesson in family values

1995 • 1,266 citations

Tumor Antigens Recognized by T Lymphocytes

1994 • 1,238 citations

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

1998 • 1,077 citations

Vascular Endothelial Growth Factor Inhibits the Development of Dendritic Cells and Dramatically Affects the Differentiation of Multiple Hematopoietic Lineages In Vivo

1998 • 933 citations

Human tumor antigens recognized by T lymphocytes.

1996 • 860 citations

Clinical significance of defective dendritic cell differentiation in cancer.

2000 • 694 citations

Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-kappa B activation in hemopoietic progenitor cells.

1998 • 524 citations

KDR Receptor: A Key Marker Defining Hematopoietic Stem Cells

1999 • 491 citations

Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function.

1999 • 452 citations

A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma.

1995 • 416 citations

Association of Vascular Endothelial Growth Factor Expression with Tumor Angiogenesis and with Early Relapse in Primary Breast Cancer

1994 • 404 citations

T cells and aging

1998 • 364 citations

Expression of the vascular endothelial growth factor (VEGF) receptor gene, KDR, in hematopoietic cells and inhibitory effect of VEGF on apoptotic cell death caused by ionizing radiation.

1995 • 311 citations

The NF-κB/Rel and IκB gene families: mediators of immune response and inflammation

1996 • 265 citations

Tumor-induced immune dysfunction

1999 • 239 citations

Dendritic Cells in Antitumor Immune Responses

1996 • 219 citations

Vascular endothelial growth factor/vascular permeability factor is detectable in the sera of tumor-bearing mice and cancer patients

1994 • 198 citations

Deficiency of Transporter for Antigen Presentation (TAP) in Tumor Cells Allows Evasion of Immune Surveillance and Increases Tumorigenesis

1999 • 167 citations

Defective Function of Langerhans Cells in Tumor-Bearing Animals Is the Result of Defective Maturation from Hemopoietic Progenitors

1998 • 154 citations

Where have all the T cells gone? Mechanisms of immune evasion by tumors

1999 • 153 citations

Toward a Genetic Analysis of Tumor Rejection Antigens

1992 • 151 citations

T cells and aging (update February 1999)

1999 • 135 citations

Myeloid progenitor cell regulatory effects of vascular endothelial cell growth factor.

1995 • 116 citations

Clinical significance of the determination of angiogenic factors

1996 • 112 citations

IL-1 and IL-6 release by tumor-associated macrophages from human ovarian carcinoma

1989 • 99 citations

Escape from Host-Antitumor Immunity

1997 • 81 citations

IMMUNOLOGIC DYSFUNCTION IN CANCER

1996 • 78 citations

New insights into the roles of ReL/NF-κB transcription factors in immune function, hemopoiesis and human disease

1999 • 74 citations

Aberrant antigen presentation by macrophages from tumor-bearing mice is involved in the down-regulation of their T cell responses.

1995 • 63 citations

Tnk1: a novel intracellular tyrosine kinase gene isolated from human umbilical cord blood CD34+/Lin-/CD38- stem/progenitor cells.

1996 • 61 citations

Immunologic Nonresponsiveness to Tumors

1998 • 54 citations

Thymic involution and thymocyte phenotypic alterations induced by murine mammary adenocarcinomas.

1989 • 50 citations

The immune system as anti-tumor sentinel: molecular requirements for an anti-tumor immune response.

1999 • 50 citations

Early Block in Maturation Is Associated with Thymic Involution in Mammary Tumor-Bearing Mice

2000 • 48 citations

Antigen-presenting activity of draining lymph node cells from mice painted with a contact allergen during ultraviolet carcinogenesis.

1991 • 42 citations

Depletion of lymphocyte subpopulations in primary and secondary lymphoid organs of mice by a transplanted granulocytosis-inducing mammary carcinoma.

1982 • 36 citations

Induction of granulocytic hyperplasia, thymic atrophy, and hypercalcemia by a selected subpopulation of a murine mammary adenocarcinoma.

1985 • 27 citations

Tumor Suppressor Gene-Derived Peptide Antigens

1995 • 8 citations

[The relationships between thymus, other immune organs and various diseases in children (analysis of 621 cases)].

1989 • 7 citations

Identification of genes encoding T cell defined tum- antigens.

1988 • 3 citations