Amino acid sequence around the thiol and reactive acyl groups of human complement component C4

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

Quantitative Film Detection of 3H and 14C in Polyacrylamide Gels by Fluorography

1975 • 4,693 citations

Atlas of Protein Sequence and Structure, 1972.

1973 • 2,408 citations

The Proteolytic Activation Systems of Complement

1981 • 479 citations

Evidence for presence of an internal thiolester bond in third component of human complement.

1980 • 368 citations

Interaction between the third complement protein and cell surface macromolecules.

1977 • 345 citations

A thiol‐ester in α₂‐macroglobulin cleaved during proteinase complex formation

1980 • 330 citations

Relation of putative thioester bond in C3 to activation of the alternative pathway and the binding of C3b to biological targets of complement.

1980 • 328 citations

The covalent-binding reaction of complement component C3

1981 • 304 citations

Evidence for an Ester Linkage between the Labile Binding Site of C3b and Receptive Surfaces

1979 • 297 citations

Human C4-binding protein. II. Role in proteolysis of C4b by C3b-inactivator.

1978 • 285 citations

Activation of the Complement System by Antibody-Antigen Complexes: The Classical Pathway

1979 • 258 citations

ISOLATION AND DESCRIPTION OF THE FOURTH COMPONENT OF HUMAN COMPLEMENT

1963 • 195 citations

Further characterization of the covalent linking reaction of α2-macroglobulin

1981 • 193 citations

FOURTH COMPONENT OF HUMAN COMPLEMENT: DESCRIPTION OF A THREE POLYPEPTIDE CHAIN STRUCTURE

1974 • 192 citations

The unactivated form of the first component of human complement, C1

1976 • 190 citations

The binding of complement component C3 to antibody-antigen aggregates after activation of the alternative pathway in human serum

1981 • 163 citations

The binding of human complement component C4 to antibody-antigen aggregates

1980 • 162 citations

Covalent binding of proteinases in their reaction with α2-macroglobulin

1980 • 160 citations

Characterization of alkylamine-sensitive site in alpha 2-macroglobulin.

1979 • 159 citations

Mechanism of action of the C3b inactivator: Requiremen for a high molecular weight cofactor (C3b-C4bINA cofactor) and production of a new C3b derivative (C3b′)

1977 • 152 citations

Methods in peptide and protein sequence analysis

1980 • 150 citations

Cleavage of C4b by C3b inactivator: production of a nicked form of C4b, C4b', as an intermediate cleavage product of C4b by C3b inactivator.

1980 • 143 citations

Third component of human complement: structural requirements for its function

1980 • 138 citations

Third component of human complement: appearance of a sulfhydryl group following chemical or enzymic inactivation

1980 • 137 citations

The Action of Ammonia on Complement. The Fourth Component

1926 • 118 citations

The isolation and structure of C4, the fourth component of human complement

1977 • 114 citations

Fourth component of human complement: studies of an amine-sensitive site comprised of a thiol component

1981 • 104 citations

Purification of the human complement control protein C3b inactivator

1980 • 98 citations

Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.

1980 • 97 citations

Sequence location of the reactive thiol ester in human α₂‐macroglobulin

1981 • 87 citations

Amino acid sequence of the tryptic peptide containing the alkylamine-reactive site from human alpha 2-macroglobulin. Identification of gamma-glutamylmethylamide.

1980 • 74 citations

Methylamine reaction and denaturation-dependent fragmentation of complement component 3. Comparison with alpha2-macroglobulin.

1980 • 71 citations

Cleavage products of C4b produced by enzymes in human serum

1975 • 69 citations

Effect of methylamine on the structure and function of the fourth component of human complement, C4.

1980 • 65 citations

Factor D̄ of the alternative pathway of human complement. Purification, alignment and N-terminal amino acid sequences of the major cyanogen bromide fragments, and localization of the serine residue at the active site

1980 • 50 citations

Human complement component C4. Structural studies on the fragments derived from C4b by cleavage with C3b inactivator

1981 • 46 citations

Intramolecular general acid catalysis in the binding reactions of α2 and complement components C3 and C4

1981 • 41 citations

Structural changes in C4 produced by cleavage with C1̄s

1980 • 20 citations

A cheap and simple method to achieve and maintain the necessary purity of reagents and solvents for automated amino acid sequence determination with the sequenator.

1979 • 4 citations