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The Biochemical and Physiological Basis of Selective Toxicity

Data up to Jan 2025

Published1976
Citations58
References235

Total Citations Per Year

Abstract

References (235)

The physiology of Insecta

1964 • 1,141 citations

Toxicology of Insecticides

1975 • 744 citations

Naturally Occurring Insecticides

1972 • 552 citations

Organophosphorus pesticides; organic and biological chemistry

1974 • 536 citations

Introduction to insect pest management

1994 • 529 citations

Acute toxicity of pesticides

1969 • 519 citations

Insecticides, Action and Metabolism.

1968 • 498 citations

Organophosphorus pesticides: Organic and biological chemistry

1975 • 498 citations

Environmental Pollution by Pesticides

1973 • 414 citations

The biochemical mode of action of pesticides

1974 • 410 citations

The Juvenile Hormones

2011 • 389 citations

Insecticides, Action and Metabolism

1968 • 334 citations

Insect Growth Regulators with Juvenile Hormone Activity

1975 • 329 citations

Detoxication Enzymes in the Guts of Caterpillars: An Evolutionary Answer to Plant Defenses?

1971 • 328 citations

Responses of Arthropod Natural Enemies to Insecticides

1975 • 316 citations

Shell thinning in avian eggs by environmental pollutants

1973 • 288 citations

Insect Hormones and Bioanalogues

1974 • 287 citations

The biochemical mode of action of pesticides

1975 • 284 citations

The laboratory evaluation of two promising new insecticides which interfere with cuticle deposition

1973 • 278 citations

Comparative metabolism of methoxychlor, methiochlor, and DDT in mouse, insects, and in a model ecosystem

1970 • 235 citations

A Photostable Pyrethroid

1973 • 233 citations

The acute oral toxicity of 369 pesticidal, pharmaceutical and other chemicals to wild birds

1972 • 227 citations

Dietary TH 6040 alters composition and enzyme activity of housefly larval cuticle

1974 • 218 citations

Biogenesis of Natural Compounds

1963 • 212 citations

1-(2,6-disubstituted benzoyl)-3-phenylurea insecticides: Inhibitors of chitin synthesis

1974 • 190 citations

CHEMISTRY OF THE INSECT CUTICLE

1974 • 190 citations

Pesticides and the soil fauna

1973 • 179 citations

Selective toxicity. The physico-chemical basis of therapy

1974 • 167 citations

Comparative toxicity, anticholinesterase action and metabolism of methyl parathion and parathion in sunfish and mice

1974 • 166 citations

The Nature and Distribution of Enzymes Catalyzing the Conjugation of Glutathione with Foreign Compounds

1974 • 163 citations

Ecological effects of pesticides on non-target species

1971 • 161 citations

OVERVIEW OF DRUG‐PROTEIN BINDING

1973 • 161 citations

Insect juvenile hormones: Chemistry and action

1973 • 157 citations

Biochemical toxicology of insecticides

1971 • 157 citations

Nutritional Factors in Insect Resistance to Chemicals

1961 • 150 citations

Advances In Comparative Physiology and Biochemistry

1975 • 146 citations

The Insect Blood—Brain Barrier

1972 • 146 citations

Pest Control Strategies for the Future

1974 • 136 citations

Concepts of Pest Management.

1971 • 134 citations

Comparative metabolism of the Cecropia juvenile hormone

1973 • 131 citations

BIOGENESIS OF NATURAL COMPOUNDS

1966 • 130 citations

Pyrethrum: The Natural Insecticide

1974 • 130 citations

Adaptation of tobacco hornworms to the ingestion of nicotine

1964 • 125 citations

The Juvenile Hormone Binding Protein in the Hemolymph of Manduca sexta Johannson ( Lepidoptera : Sphingidae )

1974 • 123 citations

The toxicology of dieldrin (HEOD). I. Long-term oral toxicity studies in mice

1973 • 123 citations

Insecticide Susceptibility of Some Common Fish Family Representatives

1970 • 122 citations

Inter-Species Variations in the Metabolism of Xenobiotics

1974 • 120 citations

Toxicity of natural and synthetic pyrethrins to rats

1972 • 120 citations

Pyrethrum, the natural insecticide.

1973 • 119 citations

Hepatic microsomal mixed-function oxidase activity of several marine species from coastal Maine.

1974 • 116 citations

Comparative patterns of drug metabolism.

1967 • 113 citations

Concepts of pest management.

1970 • 110 citations

Metabolic factors controlling duration of drug action

1962 • 107 citations

Selective Insecticides and Biological Control

1951 • 106 citations

The Toxicity of Organic Phosphorus Insecticides to Different Species of Warmwater Fishes

1962 • 106 citations

Metabolism of Nicotine by Tobacco-feeding Insects

1964 • 102 citations

Selective Toxicity

1973 • 101 citations

METABOLISM OF CECROPIA JUVENILE HORMONE IN INSECTS AND IN MAMMALS

1972 • 101 citations

Relationship between Metabolism and Differential Toxicity of Malathion in Insects and Mice1

1959 • 101 citations

Invertebrate Endocrinology and Hormonal Heterophylly

1974 • 98 citations

Insect pyrethroid-hydrolyzing esterases

1974 • 94 citations

Permeability of Insect Cuticle

1940 • 93 citations

Insensitivity of acetylcholinesterase as a factor in resistance of houseflies to the organophosphate Rabon

1973 • 92 citations

A review of sodium monofluoroacetate (compound 1080); its properties, toxicology, and use in predator and rodent control

1971 • 85 citations

Selectivity of Sumithion compared with methyl parathion. Influence of structure on anticholinesterase activity

1967 • 85 citations

The herball, or, Generall historie of plantes

1633 • 81 citations

Metabolism of Steroids in Insects

1973 • 80 citations

Insect juvenile hormones : chemistry and action

1972 • 80 citations

Pharmacological Studies on A Locust Neuromuscular Preparation

1974 • 79 citations

Drug metabolism in marine vertebrates.

1967 • 78 citations

Metabolism in vitro of diazinon and diazoxon in susceptible and resistant houseflies

1971 • 74 citations

Biochemical toxicology of insecticides

1970 • 73 citations

Mechanisms of Selective Insecticidal Action

1969 • 72 citations

Substrate-specificity and toxicological significance of pyrethroid-hydrolyzing esterases of mouse liver microsomes

1973 • 71 citations

Introduction to Insect Pest Management

1976 • 71 citations

Role of glucuronide formation in the selective toxicity of 3-trifluoromethyl-4-nitrophenol (TFM) for the sea lamprey: comparative aspects of TFM uptake and conjugation in sea lamprey and rainbow trout

1975 • 71 citations

Insect Control of the Future: Operational and Policy Aspects

1974 • 68 citations

Comparative acute oral toxicity of pesticides to six species of birds

1971 • 67 citations

Differentiation of the actions of tetrodotoxin and saxitoxin

1967 • 67 citations

Effects of Pesticides on Fish

1973 • 64 citations

Spontaneous reactivation and aging of dimethylphosphorylated acetylcholinesterase and cholinesterase

1973 • 63 citations

Metabolism in vitro of diazinon and diazoxon in rat liver

1971 • 63 citations

Mechanism of Pesticide Action

1974 • 63 citations

Relationship between Metabolism and Differential Toxicity in Insects and Mice of Diazinon, Dimethoate, Parathion, and Acethion1

1960 • 62 citations

Advances in Comparative Physiology and Biochemistry

1969 • 62 citations

Synthesis and morphogenetic activity of derivatives and analogs of aryl geranyl ether juvenoids

1974 • 61 citations

The Elimination of DDT-C14, Dieldrin-C14, and Lindane-C14from Fish following a Single Sublethal Exposure in Aquaria

1967 • 61 citations

The Synergistic Ratio of Carbaryl with Piperonyl Butoxide as an Indicator of the Distribution of Multifunction Oxidases in the Insecta12

1970 • 60 citations

The relation between physical properties and penetration of solutes into the cockroach cuticle

1963 • 60 citations

The Herbal or General History of Plants

1975 • 60 citations

Anticholinesterase action of methyl parathion, parathion and azinphosmethyl in mice and fish: Onset and recovery of inhibition

1974 • 59 citations

Environmental Quality and Safety

1977 • 58 citations

Mode of Action of Organophosphate Anthelmintics. Cholinesterase Inhibition in Ascaris lumbricoides

1966 • 57 citations

DELAYED NEUROTOXIC ACTION OF SOME ORGANOPHOSPHORUS COMPOUNDS

1969 • 56 citations

Microsomal oxidases in the honey bee, Apis mellifera (L.)

1974 • 55 citations

PERMEABILITY OF INSECT CUTICLE

1974 • 55 citations

Oxidative drug metabolism in human liver microsomes.

1971 • 51 citations

Enzymatic conjugation of diazinon with glutathione in rat and American cockroach

1972 • 50 citations

Insect Developmental Inhibitors. 3. Effects on Nontarget Aquatic Organisms

1973 • 48 citations

Spontaneous reactivation of phosphorylated and carbamylated cholinesterases.

1971 • 48 citations

Feeding Sites of the Green Peach Aphid with Respect to its Adaptation to Tobacco1

1962 • 47 citations

Peritrophic Membrane as Vehicle for DDT and DDE Excretion in Aedes aegypti Larvae

1961 • 47 citations

Cholinesterase activities of various nematode parasites and their inhibition by the organophosphate anthelmintic Haloxon

1966 • 46 citations

The Relation Between Ionization and Toxicity to Insects for Some Neuropharmacological Compounds1

1958 • 41 citations

Di-(2-chloroethyl) aryl phosphates

1964 • 41 citations

Relationship between acute toxicity and in vitro inhibition and hydrolysis of a series of carbalkoxy homologs of malathion

1966 • 41 citations

Insecticide Toxicity, Penetration of Insecticides through Rat Skin

1965 • 41 citations

Enzymatic hydrolysis of diazoxon by rat tissue homogenates

1972 • 41 citations

Toxicity of pesticides to man: risks from present levels

1967 • 39 citations

Selective toxicity of N-sulfenylated derivatives of insecticidal methylcarbamate esters

1973 • 38 citations

THE EFFECTS OF DIPHTHERIA TOXIN ON THE CECROPIA SILKWORM

1952 • 38 citations

The spontaneous and induced recovery of fly-brain cholinesterase after inhibition by organophosphates

1960 • 37 citations

Extent of plasma protein binding of amphetamine in different species

1972 • 37 citations

The metabolism of diene-organochlorine (cyclodiene) insecticides

1969 • 35 citations

Relation of the Rate of Penetration and Metabolism to the Toxicity of Sevin to Three Insect Species1

1961 • 35 citations

The effects of small applications of an organophosphorus poison, fenthion on the weaver‐bird Quelea quelea

1972 • 35 citations

Comparative metabolism and selectivity of organophosphate and carbamate insecticides.

1971 • 35 citations

Mechanisms of pesticide interactions in vertebrates

1969 • 34 citations

Mechanisms of Resistance Against Insecticides

1960 • 34 citations

Binding of insecticides to macromolecules in the blood of the rat and American cockroach

1975 • 33 citations

Oxidative metabolism of diazinon by microsomes from rat liver and cockroach fat body

1972 • 31 citations

Insect juvenile hormone activity of the stereoisomers of ethyl 3,7,11-trimethyl-2,4-dodecadienoate

1975 • 30 citations

The Penetration and Metabolism of H3-Dimethoate in Insects1

1965 • 30 citations

Comparative Biochemistry of Detoxification

1964 • 30 citations

The effect of piperonyl butoxide and triorthocresyl phosphate on the activity and metabolism of altosid (isopropyl 11-methoxy, 3,7,11-trimethyldodeca-2,4-dienoate) in Tenebrio molitor L. and Oncopeltus fasciatus (dallas)

1974 • 29 citations

Mixed-function oxidase activity toward cyclodiene insecticides in bass and bluegill sunfish

1973 • 28 citations

Penetration of Insecticides Through Rat Skin

1966 • 28 citations

Toxic effects of chlorfenvinphos in dogs and rats

1967 • 28 citations

Affinity and phosphonylation constants for the inhibition of cholinesterases by the optical isomers of O-2-butyl S-2-(dimethylammonium)ethyl ethylphosphonothioate hydrogen oxalate

1974 • 28 citations

FIELD EXPERIENCES WITH JUVENILE HORMONE MIMICS

1972 • 27 citations

Toxicology, biodegradation and efficacy of livestock pesticides.

1972 • 27 citations

The acute toxicity of dichloroalkyl aryl phosphates in relation to chemical structure

1967 • 27 citations

Mode of entry of oxime carbamates into insects

1972 • 26 citations

Purification and some properties of house cricket (Acheta domesticus) acetylcholinesterase

1974 • 26 citations

Penetration of insecticides through the isolated midgut of insects and mammals

1970 • 26 citations

Biochemistry of hypoglycin

1974 • 25 citations

A mosquito larvicide with favourable environmental properties.

1971 • 25 citations

Correlation of cholinesterase inhibition and toxicity in insects and mammals

1971 • 25 citations

The Metabolism and Toxicity of Phenols in Cats

1973 • 24 citations

Penetration of non‐electrolytes through animal integuments

1965 • 24 citations

Insect metabolism of a phenyl epoxygeranyl ether juvenoid and related compounds

1974 • 24 citations

Mechanism of low toxicity of Sumithion toward mammals

1969 • 24 citations

The Metabolism of Co-Ral (Bayer 21/199) by Tissues of the House Fly, Cattle Grub, Ox, Rat, and Mouse1

1959 • 24 citations

Effect of Ionization upon Penetration of Organophosphates to the Nerve Cord of the Cockroach1

1959 • 24 citations

Inhibition of Housefly Acetylcholinesterase by Carbamates

1967 • 24 citations

Comparative potentiation of malathion by triorthotolyl phosphate in four classes of vertebrates

1970 • 23 citations

Drug Responses in Man.

1968 • 23 citations

A comparative study of the modes of action of fluoroacetamide and fluoroacetate in the mouse and american cockroach

1963 • 23 citations

Biochemistry of selective toxicity and biodegradability: Comparative O-dealkylation by aquatic organisms

1972 • 23 citations

TOXICITY OF NICOTIAN A GOSSEI DOMIN TO MYZUS PERSICAE (SULZER)1

1962 • 22 citations

The metabolism of abate in mosquito larvae and houseflies

1972 • 22 citations

Neuromuscular Pharmacology of Insects

1975 • 21 citations

Metabolic pathways affecting toxicity of N-acetyl Zectran

1969 • 21 citations

Comparative Pharmacology.

1974 • 21 citations

Properties of the Aldrin Epoxidase System in the Gut and Fat Body of a Caddisfly Larval1

1973 • 21 citations

N‐acylation of N‐methylcarbamate insecticides and its effect on biological activity

1965 • 21 citations

Toxicity of isopropyl parathion. Effect of structure on toxicity and anticholinesterase activity

1969 • 21 citations

Some aspects of evolutionary pharmacology

1974 • 20 citations

Studies on in vivo cholinesterase inhibition and poisoning symptoms in houseflies

1967 • 20 citations

Cyanide tolerance in millipedes: The biochemical basis

1971 • 20 citations

Inhibition of choline acetylase from the house fly ( l.) and mouse

1971 • 20 citations

Physiological Factors Influencing the Toxicity of Carbamate Insecticides to Insects1

1969 • 19 citations

Recent advances in techniques for tsetse-fly control.

1967 • 18 citations

Pesticide Residues in Fish

1973 • 18 citations

Species specificity of phosphate triester anticholinesterases.

1971 • 17 citations

LOCALIZATION OF CHOLINESTERASE ACTIVITY IN HOUSEFLY THORACES: INHIBITION OF CHOLINESTERASE WITH ORGANOPHOSPHATE COMPOUNDS1

1970 • 17 citations

Selectivity of Sumithion compared with methyl parathion. Metabolism in susceptible and resistant houseflies

1967 • 17 citations

Inhibition of acetylcholinesterase from mammals and insects by carbofuran and its related compounds and their toxicities toward these animals

1972 • 16 citations

The Accumulation of DDT by the Dragonfly Nymph, Tetragoneuria

1971 • 16 citations

Vinyl phosphate insecticide sorption to proteins and its effect on cholinesterase I50 values

1967 • 16 citations

Barrier systems in insect ganglia and their implications for toxicology.

1967 • 15 citations

Selective toxicity of phoxim (phenylglyoxylonitrile oxime O,O-diethyl phosphorothioate)

1971 • 15 citations

THE RELATION BETWEEN TOXICITY AND METABOLISM OF PARAOXON IN THE FROG, MOUSE AND COCKROACH

1963 • 15 citations

Age-dependent variations in the response of several species of diptera to insecticidal chemicals

1973 • 15 citations

Metabolites and photoproducts of 3-(2-butyl)phenyl N-methylcarbamate and N-benzenesulfenyl-N-methylcarbamate

1973 • 14 citations

Acetylcholinesterase inhibition by substituted phenyl N-alkyl carbamates

1972 • 14 citations

In vitro inhibition of acetylcholinesterase by O,O-dimethyl S-aryl phosphorothioates

1973 • 14 citations

Toxicity of isopropyl parathion. Metabolism in the housefly, honey bee, and white mouse

1969 • 14 citations

The toxicity of haloxon to geese, ducks and hens, and its relationship to the stability of the DI-(2-chloroethyl) phosphoryl cholinesterase derivatives

1967 • 14 citations

Penetration of a series of dialkoxy analogs of dimethoate through the isolated gut of insects and mammals

1972 • 14 citations

The Sequential Development of Insecticide Resistance Problems inLucilia cuprinaWied. in Australia

1974 • 14 citations

Toxicity and action of fluenethyl acaricide and related compounds in the mouse, housefly and twospotted spider mite

1974 • 13 citations

DDT intoxication in rainbow trout as affected by dieldrin

1972 • 13 citations

Bioactive compounds in the aquatic environment: Studies on the mode of uptake of DDE by the aquatic midge,Chironomus tentans (diptera: Chironomidae)

1974 • 13 citations

Citrate Accumulation in Twospotted Spider Mites, House Flies, and Mice Following Treatment with the Acaricide 2-Fluoro-N-methyl-N-(1-naphthyl) Acetamide123

1972 • 13 citations

Uptake of Dieldrin by Isolated Perfused Gills of Rainbow Trout

1969 • 13 citations

Biochemical mode of action of tricyclohexylhydroxytin

1972 • 13 citations

Studies on the toxicity of dimethoate analogs and their hydrolysis by sheep liver amidase

1971 • 12 citations

Comparative metabolism of two vinyl phosphorothionate isomers (thiono Phosdrin) by the mouse and the fly

1968 • 12 citations

Occupational exposure to pesticides

2008 • 12 citations

Development of Morphogenetic Agents in Insect Control

1975 • 11 citations

Electrophysiological Action of Carbamate Insecticides in the Central Nervous System of the American Cockroach

1968 • 11 citations

Insecticidal and anticholinesterase activity of benzotriazolyl methyl and dimethylcarbamates

1973 • 10 citations

Organophosphorus poisoning: A comparative study of the toxicity of chlorfenvinphos [2-chloro-1- (2′, 4′, -dichlorophenyl) vinyl diethyl phosphate] to the pigeon, the pheasant and the Japanese Quail

1971 • 10 citations

Selective toxicity of analogs of methyl parathion

1973 • 10 citations

Absorption and Metabolism of Carbaryl by Several Insect Species1

1967 • 10 citations

Synergism of Carbaryl Toxicity in Natural Insect Populations12

1973 • 10 citations

Distribution, excretion, and metabolism of 14C-DDT in the larva and adult Trogoderma granarium in relation to toxicity

1971 • 9 citations

Toxicological Effects Produced by Some 1,3-Benzodioxoles, Catechols, and Quinones in Culex Mosquito Larvae12

1974 • 9 citations

Studies of the biochemical lesions caused by a new fluorine pesticide, N-methyl-N-(1-naphthyl)monofluoroacetamide

1968 • 9 citations

The Experimental Use of Guthion® as a Selective Fish Eradicator

1965 • 9 citations

Permeability of the ganglia of the willow aphid, Tuberolachnus salignus, to organic ions

1967 • 9 citations

Insect hormones and their bioanalogues as potential insecticides

1974 • 9 citations

Phosphorylation and affinity constants for the inhibition of acetylcholinesterase by dimethoxon analogs

1971 • 9 citations

Distribution, metabolism, elimination and toxicity of 14C-DDT in the dogfish, Squalus acanthias

1974 • 9 citations

SYNTHESIS AND ACTIVITY OF JUVENILE HORMONE ANALOGS

1972 • 8 citations

Metabolism of 2-[methoxy(methylthio)phosphinylimino]-3-ethyl-5-methyl-1,3-oxazolidine in the cotton plant and houseflies

1972 • 8 citations

Studies on hypo- and hypercholesterolemia induced in insects by filipin

1975 • 8 citations

Comparative toxicity studies on glucuronide-forming compounds in icteric and nonicteric newborn Gunn rats

1970 • 8 citations

Comparative inhibition of boll weevil, golden shiner, and white rat cholinesterases by selected photoalteration products of parathion

1973 • 7 citations

The search for a veterinary insecticide II.—Carbamates active against sheep blowfly

1967 • 7 citations

Sorption of tetrachlorvinphos insecticide (Gardona) to the hemolymph of Periplaneta americana

1975 • 7 citations

The Influence of Certain Biological and Environmental Factors on Insecticide Tolerance of the Lygus Bug, Lygus hesperus1

1964 • 7 citations

Chemistry, Biological Activity, and Uses of Formamidine Pesticides

1976 • 7 citations

Comparative properties of N‐acetyl derivatives of oxime N‐methylcarbamates and aryl N‐methylcarbamates as insecticides and acetylcholinesterase inhibitors

1971 • 6 citations

An in vitro Model System for the Production of Insect Cuticle

1974 • 6 citations

Metabolism of Fluenethyl Acaricide in the Mouse, House Fly, and Twospotted Spider Mite123

1974 • 6 citations

Correlation of Toxicity of Insecticides to the House Fly and to the Mouse

1972 • 6 citations

Comparative Aspects of the Metabolism of Pesticides

1974 • 6 citations

Absorption and Metabolism of Ruelene by Arthropods1

1962 • 6 citations

Insecticides Structure and Toxicity, Effect of Thiono Substituent on Toxicity of Fluorophosphates to Insects and Mice

1965 • 5 citations

A New Technique For Studying the Toxicology of Insecticides with House Flies by the Infusion Method, with Comparable Topical Application and Injection Results

1971 • 5 citations

Effectiveness of New Insecticides against Mosquito Larvae.

1961 • 5 citations

Investigations into carbamate insecticide selectivity

1974 • 5 citations

Spray Additives for Insecticidal Selectivity to Injurious vs. Beneficial Insects 1

1972 • 4 citations

Commercial and Experimental Organic Insecticides (1963 Revision)

1963 • 4 citations

Tests for Toxicity of Juvenile Hormone and Analogs in Mammalian Systems

1974 • 3 citations

Penetration of Gardona and DDT in Gypsy Moth Larvae and House Flies123

1972 • 3 citations

Toxicity and Anticholinesterase Activity of Halogenated Organophosphates to Boettcherisca peregrina12

1973 • 3 citations

Inhibition of flyhead acetylcholinesterase by dimethoxon analogs

1974 • 3 citations

Insecticidal and the anticholinesterase activity of m-acylamidophenyl and m-thioureidophenyl N-methylcarbamates

1972 • 2 citations

MON-0856: A Promising New Selective Insecticide1

1972 • 2 citations

Correlation of toxicity and acetylcholinesterase (AChE) inhibition in 2-alkyl substituted 1,3-benzodioxolyl-4 N-methylcarbamates and related compounds

1974 • 2 citations

Toxicology of Insecticides, Rodenticides, Herbicides, and Phytopharmaceutical Compounds

1969 • 1 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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