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The metabolism of diene-organochlorine (cyclodiene) insecticides

Data up to Jan 2025

Published1969
Citations35
References161

Total Citations Per Year

Abstract

References (161)

Personal communication

1989 • 3,268 citations

Insecticides, Action and Metabolism.

1968 • 498 citations

Insecticides, Action and Metabolism

1968 • 334 citations

A fluorimetric study of the hydroxylation of biphenyl in vitro by liver preparations of various species

1965 • 244 citations

The Ultrastructure of the Meristematic Cell

1960 • 202 citations

Effects of Acute and Chronic DDT Administration on Hepatic Microsomal Drug Metabolism in the Rat.

1963 • 193 citations

The oxidation of drugs by fishes

1968 • 178 citations

Mode of Action of Insecticide Synergists

1967 • 173 citations

THE EFFECT OF KNOWN REPEATED ORAL DOSES OF CHLOROPHENOTHANE (DDT) IN MAN

1956 • 159 citations

Stimulatory effects of chlordane on hepatic microsomal drug metabolism in the rat

1963 • 146 citations

Synergistic and Antagonistic Actions of Insecticide-Synergist Combinations and Their Mode of Action

1960 • 140 citations

Properties, effect, residues and analytics of the insecticide endosulfan

1968 • 140 citations

Metabolism of pesticides

1966 • 127 citations

Organochlorine Residues in Marine Organisms

1967 • 121 citations

Review of the Metabolism of Chlorinated Hydrocarbon Insecticides Especially in Mammals

1965 • 117 citations

Rapid identification and determination of residues of chlorinated pesticides in crops by gas-liquid chromatography

1961 • 115 citations

Chlorinated Hydrocarbon Pesticides: Degradation by Microbes

1966 • 114 citations

Insecticidal Degradation by Pseudomonas melophthora, the Bacterial Symbiote of the Apple Maggot1

1967 • 113 citations

Microsomal mixed-function oxidations: the metabolism of xenobiotics.

1965 • 95 citations

Pesticide Toxicity, Toxicity of Certain Chlorinated Hydrocarbon Insecticides for Laboratory Animals, with Special Reference to Aldrin and Dieldrin

1955 • 93 citations

Special scientific report: Wildlife

1949 • 91 citations

The epoxidation of aldrin by housefly microsomes and its inhibition by carbon monoxide

1967 • 87 citations

Organic Pesticides in the Environment

1966 • 86 citations

Metabolism of insecticides, IX(1) isolation and identification of dieldrin metabolites from urine of rabbits after oral administration of dieldrin-14C

1965 • 84 citations

Microsomal epoxidation of cyclodiene insecticides

1965 • 83 citations

The photochemical isomerization of dieldrin and endrin and effects on toxicity

1966 • 81 citations

Dieldrin: Degradation by Soil Microorganisms

1967 • 79 citations

Enzymatic Formation of Corticosteroid Glucuronides1

1955 • 78 citations

Epoxidation of aldrin, isodrin, and heptachlor by rat liver microsomes

1965 • 77 citations

Metabolism of Methylcarbamate Insecticides by the NADPH2-requiring Enzyme System from Houseflies

1967 • 75 citations

Pharmacodynamics of Dieldrin (HEOD)

1967 • 75 citations

Liver cell alteration and DDT storage in the fat of the rat induced by dietary levels of 1 to 50 p.p.m. DDT.

1950 • 74 citations

Epoxidation of Aldrin and Heptachlor in Soils As Influenced by Autoclaving, Moisture, and Soil Types12

1960 • 72 citations

Toxicity and Metabolism of Dieldrin in Rats

1964 • 70 citations

World Review of Pest Control

1964 • 70 citations

Parathion Activation by Livers of Aquatic and Terrestrial Vertebrates

1964 • 68 citations

A photoisomerisation product of dieldrin

1966 • 68 citations

Pesticide Metabolism, Fate of Aldrin and Dieldrin in the Animal Body

1956 • 68 citations

Insecticide Persistence and Translocation, Residues of Aldrin and Heptachlor in Soils and Their Translocation into Various Crops

1965 • 66 citations

Special scientific report

1955 • 65 citations

The relationship between microsomal epoxidation and lipid peroxidation in houseflies and pig liver and the inhibitory effect of derivatives of 1,3-benzodioxole (methylenedioxybenzene)

1967 • 65 citations

Storage of DDT and DDE in people with different degrees of exposure to DDT.

1958 • 64 citations

The Elimination of DDT-C14, Dieldrin-C14, and Lindane-C14from Fish following a Single Sublethal Exposure in Aquaria

1967 • 61 citations

The interaction of pesticides with other factors

1967 • 61 citations

The Conversion of Aldrin and Heptachlor to Their Epoxides in Soil1

1958 • 58 citations

The effect of pyrethrin synergists, especially sesamex, on the insecticidal potency of hexachlorocyclopentadiene derivatives (“cyclodiene” insecticides) in the adult housefly, Musca Domestica L

1964 • 57 citations

Isolation of an epoxide metabolite from fat tissues of dogs fed heptachlor.

1953 • 56 citations

Insecticide Movement in Plants, Translocation of Some Chlorinated Hydrocarbon Insecticides into the Aerial Parts of Pea Plants

1960 • 54 citations

Interaction between microsomal electron transport systems of trout and male rat in cyclodiene epoxidation

1967 • 51 citations

Excretion and distribution of aldrin-14C and its metabolites after oral administration for a long period of time

1964 • 49 citations

ORGANOCHLORINE INSECTICIDES AND THE STIMULATION OF LIVER MICROSOME ENZYMES*

1969 • 48 citations

Persistent glycosides of metabolites of methylcarbamate insecticide chemicals formed by hydroxylation in bean plants

1967 • 47 citations

Interactions between DDT Analogs and Microsomal Epoxidase Systems

1966 • 47 citations

The effects on birds of certain chlorinated insecticides used as seed dressings

1963 • 46 citations

Metabolism, Storage, and Excretion of C14-Endosulfan in the Mouse1

1966 • 45 citations

Soil microbial degradation of Aldrin

1968 • 45 citations

Comparative Response of Insects and Mammals to Certain Halogenated Hydrocarbons Used as Insecticides

1955 • 44 citations

Organochlorine Insecticides: Concentrations in Human Blood and Adipose Tissue

1966 • 44 citations

Insektizide im Stoffwechsel, II. Umwandlung von Aldrin‐[14C] und Dieldrin‐[14C] durch Mikroorganismen, Leberhomogenate und Moskito‐Larven

1962 • 44 citations

The Mode of Action of Aldrin and Dieldrin in Periplaneta Americana (L.)1

1956 • 44 citations

The Absorption and Metabolism of C14-Labeled Endosulfan in the House Fly12

1965 • 42 citations

Mechanisms of Resistance of the Adult Housefly (Musca domestica) to ‘Cyclodiene’ Insecticides

1960 • 41 citations

Dynamics of Organochlorine Insecticides in Vertebrates and Ecosystems

1967 • 40 citations

Some Effects of Heptachlor on Bluegills (Lepomis macrochirus)

1966 • 40 citations

Insecticide Storage in Fat, Storage of Heptachlor Epoxide in Body Fat and Its Excretion in Milk of Dairy Cows Fed Heptachlor in Their Diets

1965 • 39 citations

Fate of C14-Carbonyl-Labeled Aryl Methylcarbamate Insecticide Chemicals in and on Bean Plants

1966 • 38 citations

ORGANO-CHLORINE INSECTICIDE CONTENT OF HUMAN ADIPOSE TISSUE IN SOUTH-EASTERN ENGLAND

1965 • 38 citations

Stimulation of dieldrin metabolism by DDT

1967 • 37 citations

Insecticide Metabolism, The Detection of Dieldrin Metabolites in Human Urine

1962 • 36 citations

Residues and some effects of chlorinated hydrocarbon insecticides in biological material

1965 • 36 citations

Insecticide Interactions Affecting Residue Storage in Animal Tissues

1966 • 35 citations

Drug effects on dieldrin storage in rat tissue

1966 • 35 citations

Dealkylation of alkoxybiphenyls by trout and frog liver preparations

1967 • 35 citations

The metabolism of contact insecticides in stored grains

1967 • 35 citations

Mechanisms of Resistance Against Insecticides

1960 • 34 citations

Research in pesticides.

1965 • 34 citations

The metabolite of heptachlor, its estimation storage, and toxicity.

1953 • 34 citations

Effect of Formulation and Mode of Application of Aldrin on the Loss of Aldrin and Its Epoxide from Soils and Their Translocation into Carrots1

1964 • 33 citations

The Fate of Dieldrin in Insects1

1965 • 33 citations

Chlorinated Insecticides: Fate in Aqueous Suspensions Containing Mosquito Larvae

1964 • 32 citations

Inhibition of the Conversion of Aldrin to Dieldrin in Soils with Methylenedioxyphenyl Synergists12

1963 • 32 citations

Metabolism of the Carcinogen 2-Acetylaminofluorene by Rainbow Trout.

1967 • 31 citations

Relations between Structure, Metabolism and Toxicity of the ‘Cyclodiene’ Insecticides

1963 • 30 citations

The Conversion of Heptachlor to Its Epoxide on Plants1

1958 • 30 citations

Drug Effects on Dieldrin Storage in Rat Tissue

1966 • 30 citations

Some Effects of Heptachlor and DDT on New Brunswick Woodcocks

1965 • 27 citations

Dynamics of Insect Toxicology—A Mathematical and Graphical Evaluation of the Relationship Between Insect Toxicity and Rates of Penetration and Detoxication of Insecticides1

1968 • 27 citations

Metabolism of aldrin and dihydroaldrin by houseflies ( L.) and by housefly and pig liver microsomes

1966 • 25 citations

The Metabolism of Heptachlor by Resistant and Susceptible House Flies

1958 • 25 citations

The metabolism of some cyclodiene insecticides in relation to dieldrin resistance in the adult housefly, Musca domestica L.

1964 • 25 citations

Mechanisms of Resistance of Adult Houseflies to the Insecticide Dieldrin

1959 • 25 citations

Pharmacodynamics of Dieldrin in Pigeons

1967 • 24 citations

The Relationship of the Levels of Insecticide Contamination of Crop Seeds to Their Fat Content and Soil Concentration of Aldrin, Heptachlor, and Their Epoxides1

1966 • 24 citations

Structure-activity Relationships among Insecticidal Compounds derived from Chlordene

1965 • 24 citations

The Absorption, Distribution, and Fate of C14-Aldrin and C14-Dieldrin by Susceptible and Resistant House Flies

1964 • 24 citations

The Conversion of Aldrin to Dieldrin on Plants1

1958 • 23 citations

Studies of Endosulfan in Bean Plants by Paper and Gas Chromatography12

1963 • 23 citations

Metabolism of Insecticides by Various Insect Species

1960 • 22 citations

Metabolism of C14 -Dieldrin by Dieldrin-Resistant Culex pipiens quinquefasciatus Mosquitoes1

1964 • 21 citations

Insecticide residues in wheat grown in soil treated with aldrin and endrin

1967 • 21 citations

Fate of Aldrin and Dieldrin in Locusts

1961 • 21 citations

Identification of metabolites of dieldrin (HEOD) in the faeces and urine of rats

1968 • 20 citations

Excretion of Heptachlor Epoxide in Milk of a Dairy Cow Fed Heptachlor

1953 • 20 citations

Survey of quantitative relationships between ingestion and storage of aldrin and dieldrin in animals and man

1967 • 20 citations

The toxicity of α-dihydroheptachlor and related compounds to the housefly ( L.) and their metabolism by housefly and pig liver microsomes

1967 • 20 citations

Cyclodien‐Insektizide, IV. Synthese und Struktur von Isomeren des Chlordans

1966 • 20 citations

Cyclodien‐Insektizide, II. Synthese und Struktur von Heptachlor‐methano‐tetrahydroindanen

1966 • 17 citations

Absorption and translocation of dieldrin by forage crops

1967 • 17 citations

Disappearance of Endrin from Fish and other Materials of a Pond Environment

1961 • 17 citations

The metabolism of dihydrochlordene and related compounds by housefly ( L.) and pig liver microsomes

1967 • 17 citations

Metabolismus des Thiodans® in Insekten

1966 • 16 citations

Metabolism of insecticides, VIII (1): Excretion, distribution and metabolism of α-chlordan-14C by rats

1964 • 16 citations

Effect of Carbon Monoxide on Metabolism of Insecticides in vivo

1967 • 15 citations

Insecticide Residues, Endrin Content of Eggs and Body Tissue of Poultry Receiving Endrin in Their Daily Diet

1959 • 15 citations

The Resolution and Chemical and Biological Characterization of Some Constituents of Technical Chlordane12

1952 • 15 citations

Notes

1962 • 15 citations

Significance of the Epoxidation of the Isomeric Insecticides Aldrin and Isodrin by the Adult Housefly in vivo

1963 • 15 citations

Excretion of Heptachlor Epoxide in the Milk of Dairy Cows Fed Heptachlor-Sprayed Forage and Technical Heptachlor

1955 • 14 citations

Absorption and Metabolism of DDT, Toxaphene, and Chlordane by Resistant House Flies as Determined by Bioassay

1952 • 14 citations

Woodcock Reproduction in DDT-Sprayed Areas of New Brunswick

1960 • 14 citations

Insect Resistance to Insecticides, The Fate of Cyclodiene Insecticides Administered to Susceptible and Resistant Houseflies

1963 • 13 citations

Insektizide im Stoffwechsel, VI. Umwandlung von Telodrin‐[14C] durch Mikroorganismen und Moskitolarven

1964 • 13 citations

Metabolites in Urine of Rats on Diets containing Aldrin or Dieldrin

1965 • 13 citations

Relationship of dietary intake to concentration of dieldrin and endrin in dogs

1967 • 12 citations

Effects of Application Methods on the Toxicity and Distribution of Dieldrin in House Flies1

1967 • 12 citations

Insecticide absorbed by the Central Nervous System of Susceptible and Resistant Cockroaches exposed to Dieldrin

1963 • 12 citations

Insecticide Residues, Residues in Fatty Tissues and Meat of Cattle Grazing on Pastures Treated with Granular Heptachlor

1963 • 12 citations

Die Ausscheidung von Aldrin-C<sup>14</sup> und Dieldrin-C<sup>14</sup> sowie ihrer Metaboliten durch die Galle

1963 • 11 citations

Occurrence of a Toxic Non-Aldrin Residue in Carrots Grown on Aldrin-Treated Soil1

1958 • 11 citations

Metabolism of 14C-labelled Insecticides in Microorganisms, Insects and Mammals

1967 • 11 citations

Insecticide Residues in Butterfat, Residues of Heptachlor Epoxide in Butterfat of Dairy Cows Grazing Pastures Treated with Granular Heptachlor

1962 • 11 citations

Versuche über die Persistenz des Insektizides Endosulfan im pflanzlichen und tierischen Organismus

1967 • 11 citations

Infrared Identification of Chlorinated Insecticides in Tissues of Poisoned Fish

1966 • 11 citations

Isotope-Labeled Insecticides, Synthesis of Carbon-14-Labeled Aldrin and Dieldrin

1960 • 9 citations

A Study of Dieldrin in the House Fly Central Nervous System in Relation to Dieldrin Resistance

1967 • 9 citations

Cross-tolerances of dieldrin-resistant flies and mosquitos to various cyclodiene insecticides.

1962 • 9 citations

Insecticide Residues, Endrin Content of Body Tissues of Steers, Lambs, and Hogs Receiving Endrin in Their Daily Diet

1958 • 8 citations

The endrin content of eggs and body tissue of poultry receiving endrin in their daily diet.

1959 • 8 citations

Insecticide Residues, Endrin Content of Milk and Body Tissues of Dairy Cows Receiving Endrin Daily in Their Diet

1958 • 8 citations

Pesticides in Animal Feeds, Effects of Feeding Dieldrin- and Heptachlor-Treated Alfalfa Hay to Dairy Cows

1956 • 8 citations

DIELDRIN UPTAKE FROM SOIL BY WHEAT PLANTS

1965 • 7 citations

Residues of organochlorine insecticides in dead birds in the United Kingdom.

1967 • 7 citations

Pest Infestation Research 1956

1957 • 6 citations

Metabolism of Insecticides

1970 • 6 citations

Metabolites of dieldrin (HEOD) in the urine and faeces of rats.

1968 • 6 citations

Metabolism of .beta.-dihydroheptachlor-14C in soil and by microorganisms

1968 • 6 citations

Metabolism of insecticides. Microsynthesis of .beta.-dihydroheptachlor-14C

1968 • 6 citations

Toxicological Action and Metabolic Fate of Chlordan

1950 • 6 citations

Insektizide im Stoffwechsel. XI. Ausscheidung, Verteilung und Umwandlung von Aldrín-<sup>14</sup>C und Dieldrin-<sup>14</sup>C in der Ratte

1966 • 5 citations

[The metabolism of pesticides in mammals].

1967 • 5 citations

Residues from 1-Bromochlordene Against European Corn Borer on Corn1

1965 • 5 citations

Secretion of Telodrin in the Milk of Cows Fed Varying Levels of Telodrin

1964 • 4 citations

739. The synthesis of 14C-labelled 1 : 2 : 3 : 4 : 10 : 10-hexachloro-6 : 7-epoxy - 1 : 4 : 4a; 5 : 6 : 7 : 8 : 8a - octahydro-exo- 1 : 4-exo-5 : 8-dimethanonaphthalene (endrin)

1958 • 4 citations

Fate of Dieldrin Applied Topically to Stable Flies Susceptible and Resistant to Dieldrin

1966 • 4 citations

Studies on the Toxicity of <i>β</i>-Dihydroheptachlor

1965 • 4 citations

Insektizide im Stoffwechsel. XII. Isolierung und Identifizierung von Metaboliten des Aldrin-<sup>14</sup>C aus dem Urin von Kaninchen

1966 • 4 citations

Effects on Beef Cattle of prolonged Treatment with a DDT Spray.

1952 • 4 citations

457 Duration of action of drugs as affected by tissue distribution

1961 • 2 citations

Problems of Application and Action of Thiodan Studied with S 35 -Labelled Insecticide

1963 • 2 citations

Mechanisms of resistance to chlorohydrocarbon insecticides.

1968 • 2 citations

Der Stoffwechsel von Pesticiden in Säugetieren

1967 • 1 citations

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The metabolism of diene-organochlorine (cyclodiene) insecticides (1969) – Reviews of Environmental Contamination and Toxicology | Metascience Observatory Explorer