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Loss of heterozygosity and microsatellite instability in breast hyperplasia. No obligate correlation of these genetic alterations with subsequent malignancy.

Data up to Jan 2025

Published1997
Citations52
References48

Total Citations Per Year

Abstract

References (48)

Genetic Alterations during Colorectal-Tumor Development

1988 • 6,691 citations

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

1993 • 2,711 citations

The 1993–94 Généthon human genetic linkage map

1994 • 1,870 citations

Risk Factors for Breast Cancer in Women with Proliferative Breast Disease

1985 • 1,817 citations

A second-generation linkage map of the human genome

1992 • 1,721 citations

ABC of breast diseases: Breast cancer---epidemiology, risk factors, and genetics

2000 • 1,564 citations

Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.

1977 • 1,372 citations

Atypical hyperplastic lesions of the female breast. A long-term follow-up study

1985 • 963 citations

Intraductal carcinoma of the breast: Follow-up after biopsy only

1982 • 604 citations

Microsatellite instability: marker of a mutator phenotype in cancer.

1994 • 552 citations

Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation

1994 • 496 citations

A Prospective Study of Benign Breast Disease and the Risk of Breast Cancer

1992 • 491 citations

The mutation rate and cancer

1996 • 459 citations

Interobserver Reproducibility in the Diagnosis of Ductal Proliferative Breast Lesions Using Standardized Criteria

1992 • 414 citations

Instability of short tandem repeats (microsatellites) in human cancers

1994 • 413 citations

Combined histologic and cytologic criteria for the diagnosis of mammary atypical ductal hyperplasia

1992 • 373 citations

Epidemiology and Prevention of Breast Cancer

1996 • 365 citations

Microsatellite instability in inherited and sporadic neoplasms

1995 • 257 citations

Subsequent breast carcinoma risk after biopsy with atypia in a breast papilloma

1996 • 254 citations

Anatomic markers of human premalignancy and risk of breast cancer

1990 • 219 citations

Atypical ductal hyperplasia of the breast: clonal proliferation with loss of heterozygosity on chromosomes 16q and 17p.

1995 • 207 citations

Deficient DNA repair capacity, a predisposing factor in breast cancer

1996 • 198 citations

Microsatellite instability and loss of heterozygosity in breast cancer.

1994 • 189 citations

Evidence of cumulative gene losses with progression of premalignant epithelial lesions to carcinoma of the bronchus

1996 • 182 citations

A prospective study of benign breast disease and the risk of breast cancer

1992 • 178 citations

Genetic divergence in the clonal evolution of breast cancer.

1996 • 164 citations

Mutations in Human Breast Cancer: An Overview

1989 • 155 citations

Detection of allelic imbalance indicates that a proportion of mammary hyperplasia of usual type are clonal, neoplastic proliferations.

1996 • 120 citations

Molecular genetic studies of early breast cancer evolution

1994 • 120 citations

Loss of heterozygosity in ductal carcinoma in situ of the breast

1995 • 113 citations

Loss of heterozygosity on the long arm of chromosome 11 in nasopharyngeal carcinoma.

1996 • 112 citations

Loss of heterozygosity at chromosome 11 in breast cancer: association of prognostic factors with genetic alterations

1995 • 84 citations

Potential Role of the Inactivated X Chromosome in Ovarian Epithelial Tumor Development

1996 • 80 citations

p53 mutations are confined to the comedo type ductal carcinoma in situ of the breast. Immunohistochemical and sequencing data.

1994 • 78 citations

Frequent alterations of chromosome 1 in ductal carcinoma in situ of the breast.

1995 • 67 citations

Microsatellite instability in preinvasive and invasive head and neck squamous carcinoma.

1996 • 61 citations

Loss of heterozygosity on chromosome 11 q in breast cancer.

1995 • 50 citations

Determination of B-Cell Clonality in Paraffin-embedded Endoscopic Biopsy Specimens of Abnormal Lymphocytic Infiltrates and Gastrointestinal Lymphoma by Polymerase Chain Reaction

1994 • 49 citations

Microsatellite alterations indicating monoclonality in atypical hyperplasias associated with breast cancer

1997 • 43 citations

Loss of heterozygosity on the short arm of chromosome 8 in male breast carcinomas.

1995 • 41 citations

Molecular analysis of premalignant and carcinoma in situ lesions of the human breast.

1996 • 35 citations

Benign breast disease: absence of genetic alterations at several loci implicated in breast cancer malignancy.

1995 • 34 citations

Clonal analysis of benign and malignant human breast tumors by means of polymerase chain reaction

1995 • 26 citations

Mutation at chromosome 11q23 in human non‐familial breast cancer: A microdissection microsatellite analysis

1995 • 26 citations

Mutation of the TP53 gene and allelic imbalance at chromosome 17p13 in ductal carcinoma in situ

1996 • 21 citations

Definition of regions of the human genome affected by loss of heterozygosity in primary human breast tumors

1993 • 16 citations

A prospective study of benign breast disease and the risk of breast cancer

1992 • 11 citations

Loss of Heterozygosity on Chromosome 11q13 in Microdissected Human Male Breast Carcinomas

1995 • 9 citations

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Loss of heterozygosity and microsatellite instability in breast hyperplasia. No obligate… (1997) – PubMed | Metascience Observatory Explorer