Age-related expansion of functionally inefficient cells with markers of natural killer activity in Down's syndrome

Subpopulations of human natural killer cells defined by expression of the Leu-7 (HNK-1) and Leu-11 (NK-15) antigens.

1983 • 852 citations

Spontaneous human lymphocyte-mediated cytotoxicity against tumor target cells. IX. The quantitation of natural killer cell activity

1981 • 703 citations

Cytotoxicity mediated by human Fc receptors for IgG

1989 • 381 citations

Genetic syndromes in man with potential relevance to the pathobiology of aging.

1978 • 290 citations

A subset of natural killer cells in peripheral blood displays a mature T cell phenotype.

1986 • 205 citations

Postnatal expansion of the natural killer and keller cell population in humans identified by the monoclonal HNK-1 antibody.

1982 • 179 citations

THYMIC HORMONE DEFICIENCY IN NORMAL AGEING AND DOWN'S SYNDROME: IS THERE A PRIMARY FAILURE OF THE THYMUS?

1984 • 157 citations

CD antigens 1989

1989 • 102 citations

‘Nonspecific’ MHC-unrestricted killer cells and their receptors

1987 • 98 citations

Lymphocytes infiltrating human ovarian tumors. I. Role of Leu-19 (NKH1)-positive recombinant IL-2-activated cultures of lymphocytes infiltrating human ovarian tumors.

1988 • 94 citations

Life tables for Down syndrome

1989 • 88 citations

Deficiency of autologous mixed lymphocyte reactions and serum thymic factor level in Down's syndrome.

1981 • 87 citations

Disproportionate Expansion of a Minor T Cell Subset in Patients with Lymphadenopathy Syndrome and Acquired Immunodeficiency Syndrome

1985 • 86 citations

Age-Related Changes in Humoral and Cell- Mediated Immunity in Down Syndrome Children Living at Home

1987 • 76 citations

Oral zinc supplementation in Down's syndrome: restoration of thymic endocrine activity and of some immune defects

1988 • 62 citations

Chromosome clues to acute leukemia in Down's syndrome

1986 • 56 citations

T AND B LYPMHOCYTE SUBPOPULATIONS IN DOWN'S SYNDROME. A STUDY ON NON‐INSTITUTIONALISED SUBJECTS

1978 • 54 citations

Cell-mediated immunodeficiency in Down's syndrome: normal IL-2 production but inverted ratio of T cell subsets.

1984 • 43 citations

Lymphocyte subpopulations in Down's syndrome: high percentage of circulating HNK-1+, Leu 2a+ cells.

1984 • 41 citations

Age-related increase of mitomycin C-induced micronuclei in lymphocytes from Down's syndrome subjects

1990 • 36 citations

IgG Subclass Deficiency in Patients with Down's Syndrome and Aberrant Hepatitis B Vaccine Response

1988 • 36 citations

Natural killer cell function in trisomy-21 (Down's syndrome).

1982 • 34 citations

Methodological Considerations for Implementation of Lymphocyte Subset Analysis in a Clinical Reference Laboratory

1986 • 33 citations

The expression of CD18 is increased on Trisomy 21 (Down syndrome) lymphoblastoid cells.

1988 • 31 citations

Alterations of the Capping Phenomenon on Lymphocytes from Aged and Down’s Syndrome Subjects

1984 • 29 citations

Time, a quality‐control parameter in flow cytometry

1987 • 22 citations

Fetal thymic differentiation in Down's syndrome.

1989 • 17 citations

Analysis of blood cell populations, plasma zinc and natural killer cell activity in young children with Down's syndrome*

1988 • 16 citations

LAK activity is inducible in blood mononuclear cells from human fetus

1990 • 12 citations