The expression of CD18 is increased on Trisomy 21 (Down syndrome) lymphoblastoid cells.

A human leukocyte differentiation antigen family with distinct alpha-subunits and a common beta-subunit: the lymphocyte function-associated antigen (LFA-1), the C3bi complement receptor (OKM1/Mac-1), and the p150,95 molecule.

1983 • 888 citations

Inherited deficiency of the Mac-1, LFA-1, p150,95 glycoprotein family and its molecular basis.

1984 • 495 citations

A human lymphocyte‐associated antigen involved in cell‐mediated lympholysis

1983 • 315 citations

Definition of a common leukocyte cell-surface antigen (Lp95-150) associated with diverse cell-mediated immune functions.

1983 • 305 citations

The β2-microglobulin gene is on chromosome 15 and not in the HL-A region

1975 • 274 citations

LFA-1 immunodeficiency disease. Definition of the genetic defect and chromosomal mapping of alpha and beta subunits of the lymphocyte function-associated antigen 1 (LFA-1) by complementation in hybrid cells.

1986 • 163 citations

LONGEVITY AND MORTALITY IN DOWN'S SYNDROME

1982 • 157 citations

Assignment of the major histocompatibility complex to a region of the short arm of human chromosome 6.

1977 • 151 citations

Thymic deficiency in Down's syndrome.

1979 • 130 citations

Abnormalities of the in vitro cellular and humoral responses to tetanus and influenza antigens with concomitant numerical alterations in lymphocyte subsets in Down syndrome (trisomy 21).

1986 • 79 citations

Human lymphocyte function associated antigen-1 (LFA-1): identification of multiple antigenic epitopes and their relationship to CTL-mediated cytotoxicity.

1983 • 75 citations

Expression of human transferrin receptor is controlled by a gene on chromosome 3: Assignment using species specificity of a monoclonal antibody

1982 • 71 citations

Gene dosage and gene expression in the HLA region: Evidence from deletion variants

1982 • 66 citations

Identification of a cell‐surface glycoprotein mediating cell adhesion in EBV‐immortalized normal B cells

1986 • 46 citations

Genetic and biochemical characterization of a human surface determinant on somatic cell hybrids: The 4F2 antigen

1982 • 41 citations

Genetic assignment of GP90, leukocyte adhesion glycoprotein to human chromosome 21

1986 • 40 citations

The Biology of Down Syndrome

1985 • 18 citations