Preclinical assessment of anti-cancer therapeutic strategies using in vivo videomicroscopy.

Changing views of the role of matrix metalloproteinases in metastasis

1997 • 1,585 citations

Multistep Nature of Metastatic Inefficiency

1998 • 1,186 citations

Angiogenesis: role of calcium-mediated signal transduction.

1995 • 283 citations

Steps in tumor metastasis: new concepts from intravital videomicroscopy

1995 • 268 citations

Suppression of the Tumorigenic and Metastatic Abilities of Murine B16-F10 Melanoma Cells In Vivo by the Overexpression of the Tissue Inhibitor of the Metalloproteinases-1

1994 • 221 citations

Technical considerations for studying cancer metastasis in vivo.

1997 • 193 citations

Orthotopic implantation of human colon carcinomas into nude mice provides a valuable model for the biology and therapy of metastasis

1991 • 181 citations

Fate of melanoma cells entering the microcirculation: over 80% survive and extravasate.

1995 • 177 citations

Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth.

1994 • 160 citations

Mammary carcinoma cell lines of high and low metastatic potential differ not in extravasation but in subsequent migration and growth

1994 • 135 citations

Protease inhibitors: Role and potential therapeutic use in human cancer

1994 • 134 citations

Early interactions of cancer cells with the microvasculature in mouse liver and muscle during hematogenous metastasis: videomicroscopic analysis

1993 • 129 citations

In vivo efficacy of a novel inhibitor of selected signal transduction pathways including calcium, arachidonate, and inositol phosphates.

1992 • 116 citations

Independence of metastatic ability and extravasation: metastatic ras-transformed and control fibroblasts extravasate equally well.

1996 • 111 citations

Modulation of tumor cell gene expression and phenotype by the organspecific metastatic environment

1995 • 109 citations

Matrix metalloproteinase inhibitors: A novel class of anticancer agents

1995 • 98 citations

The matrix metalloproteinase inhibitor batimastat inhibits angiogenesis in liver metastases of B16F1 melanoma cells.

1999 • 96 citations

Early Steps in Hematogenous Metastasis of B16F1 Melanoma Cells in Chick Embryos Studied by High-Resolution Intravital Videomicroscopy

1992 • 92 citations

Up-regulation of TIMP-1 expression in B16-F10 melanoma cells suppresses their metastatic ability in chick embryo

1992 • 76 citations

Kinetics of red blood cell passage through interendothelial slits into venous sinuses in rat spleen, analyzed by in vivo microscopy

1987 • 76 citations

The biology of human cancer metastasis

1991 • 73 citations

Intravital videomicroscopy of the chorioallantoic microcirculation: A model system for studying metastasis

1992 • 67 citations

Effects of the Disintegrin Eristostatin on Individual Steps of Hematogenous Metastasis

1995 • 61 citations

Promising new agents under development by the Division of Cancer Treatment, Diagnosis, and Centers of the National Cancer Institute.

1997 • 57 citations

Integrin VLA-2 (alpha2beta1) function in postextravasation movement of human rhabdomyosarcoma RD cells in the liver.

1996 • 52 citations

Microcirculatory changes in livers of mice infected with murine hepatitis virus. Evidence from microcorrosion casts and measurements of red cell velocity

1988 • 25 citations